| Full name: transgelin 2 | Alias Symbol: KIAA0120|HA1756 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 8407 | HGNC ID: HGNC:11554 | Ensembl Gene: ENSG00000158710 | OMIM ID: 604634 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAGLN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAGLN2 | 8407 | 200916_at | 0.8558 | 0.0285 | |
| GSE20347 | TAGLN2 | 8407 | 200916_at | 0.3281 | 0.0703 | |
| GSE23400 | TAGLN2 | 8407 | 200916_at | 0.6729 | 0.0000 | |
| GSE26886 | TAGLN2 | 8407 | 200916_at | 0.3695 | 0.1395 | |
| GSE29001 | TAGLN2 | 8407 | 200916_at | 0.4499 | 0.1404 | |
| GSE38129 | TAGLN2 | 8407 | 200916_at | 0.6133 | 0.0012 | |
| GSE45670 | TAGLN2 | 8407 | 200916_at | 0.8349 | 0.0000 | |
| GSE53622 | TAGLN2 | 8407 | 72861 | 0.3508 | 0.0000 | |
| GSE53624 | TAGLN2 | 8407 | 72861 | 0.4036 | 0.0000 | |
| GSE63941 | TAGLN2 | 8407 | 200916_at | 0.6103 | 0.2876 | |
| GSE77861 | TAGLN2 | 8407 | 200916_at | 1.0312 | 0.0063 | |
| GSE97050 | TAGLN2 | 8407 | A_33_P3319760 | 0.7620 | 0.1074 | |
| SRP007169 | TAGLN2 | 8407 | RNAseq | 0.0296 | 0.9300 | |
| SRP008496 | TAGLN2 | 8407 | RNAseq | 0.1887 | 0.3939 | |
| SRP064894 | TAGLN2 | 8407 | RNAseq | 0.8863 | 0.0005 | |
| SRP133303 | TAGLN2 | 8407 | RNAseq | 0.9380 | 0.0000 | |
| SRP159526 | TAGLN2 | 8407 | RNAseq | 0.8012 | 0.0003 | |
| SRP193095 | TAGLN2 | 8407 | RNAseq | 0.3699 | 0.0323 | |
| SRP219564 | TAGLN2 | 8407 | RNAseq | 0.8230 | 0.0406 | |
| TCGA | TAGLN2 | 8407 | RNAseq | 0.1302 | 0.0012 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAGLN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAGLN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAGLN2 | 8407 | 10 | 0 | 20 | |
| GSE20123 | TAGLN2 | 8407 | 10 | 0 | 20 | |
| GSE43470 | TAGLN2 | 8407 | 7 | 2 | 34 | |
| GSE46452 | TAGLN2 | 8407 | 2 | 1 | 56 | |
| GSE47630 | TAGLN2 | 8407 | 14 | 0 | 26 | |
| GSE54993 | TAGLN2 | 8407 | 0 | 5 | 65 | |
| GSE54994 | TAGLN2 | 8407 | 16 | 0 | 37 | |
| GSE60625 | TAGLN2 | 8407 | 0 | 0 | 11 | |
| GSE74703 | TAGLN2 | 8407 | 7 | 2 | 27 | |
| GSE74704 | TAGLN2 | 8407 | 4 | 0 | 16 | |
| TCGA | TAGLN2 | 8407 | 43 | 3 | 50 |
Total number of gains: 113; Total number of losses: 13; Total Number of normals: 362.
Somatic mutations of TAGLN2:
Generating mutation plots.
Highly correlated genes for TAGLN2:
Showing top 20/1368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAGLN2 | RTKN | 0.736706 | 7 | 0 | 7 |
| TAGLN2 | ZNF114 | 0.734092 | 3 | 0 | 3 |
| TAGLN2 | HDGF | 0.728689 | 12 | 0 | 11 |
| TAGLN2 | MRPS12 | 0.711385 | 9 | 0 | 8 |
| TAGLN2 | EME1 | 0.708745 | 4 | 0 | 4 |
| TAGLN2 | C4orf48 | 0.706628 | 6 | 0 | 5 |
| TAGLN2 | INO80B | 0.696643 | 4 | 0 | 4 |
| TAGLN2 | SHKBP1 | 0.692227 | 6 | 0 | 5 |
| TAGLN2 | CCT3 | 0.691524 | 10 | 0 | 9 |
| TAGLN2 | TMEM63B | 0.691227 | 5 | 0 | 4 |
| TAGLN2 | TTYH3 | 0.69041 | 7 | 0 | 5 |
| TAGLN2 | UHRF1 | 0.686137 | 7 | 0 | 6 |
| TAGLN2 | EMC10 | 0.684797 | 5 | 0 | 5 |
| TAGLN2 | DCBLD1 | 0.671362 | 6 | 0 | 5 |
| TAGLN2 | CDCA2 | 0.667972 | 5 | 0 | 4 |
| TAGLN2 | APLNR | 0.667647 | 4 | 0 | 3 |
| TAGLN2 | PTK7 | 0.666526 | 11 | 0 | 8 |
| TAGLN2 | CDH3 | 0.664028 | 10 | 0 | 7 |
| TAGLN2 | SRM | 0.663959 | 11 | 0 | 10 |
| TAGLN2 | WDR66 | 0.663014 | 7 | 0 | 5 |
For details and further investigation, click here
