| Full name: centromere protein J | Alias Symbol: CPAP|BM032|LAP|LIP1|Sas-4|SASS4|SCKL4 | ||
| Type: protein-coding gene | Cytoband: 13q12.12-q12.13 | ||
| Entrez ID: 55835 | HGNC ID: HGNC:17272 | Ensembl Gene: ENSG00000151849 | OMIM ID: 609279 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CENPJ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPJ | 55835 | 223513_at | 0.5393 | 0.2322 | |
| GSE20347 | CENPJ | 55835 | 220885_s_at | 0.0922 | 0.2078 | |
| GSE23400 | CENPJ | 55835 | 220885_s_at | -0.0680 | 0.0135 | |
| GSE26886 | CENPJ | 55835 | 223513_at | 1.6014 | 0.0001 | |
| GSE29001 | CENPJ | 55835 | 220885_s_at | 0.1210 | 0.6289 | |
| GSE38129 | CENPJ | 55835 | 220885_s_at | 0.1744 | 0.0432 | |
| GSE45670 | CENPJ | 55835 | 223513_at | 0.7645 | 0.0038 | |
| GSE53622 | CENPJ | 55835 | 36921 | 0.7478 | 0.0000 | |
| GSE53624 | CENPJ | 55835 | 36921 | 0.9785 | 0.0000 | |
| GSE63941 | CENPJ | 55835 | 223513_at | 0.7717 | 0.1249 | |
| GSE77861 | CENPJ | 55835 | 220885_s_at | 0.0981 | 0.5275 | |
| GSE97050 | CENPJ | 55835 | A_32_P219116 | 0.2607 | 0.3973 | |
| SRP007169 | CENPJ | 55835 | RNAseq | 1.1159 | 0.0408 | |
| SRP008496 | CENPJ | 55835 | RNAseq | 1.3028 | 0.0033 | |
| SRP064894 | CENPJ | 55835 | RNAseq | 1.0980 | 0.0000 | |
| SRP133303 | CENPJ | 55835 | RNAseq | 0.9901 | 0.0000 | |
| SRP159526 | CENPJ | 55835 | RNAseq | 0.7313 | 0.0074 | |
| SRP193095 | CENPJ | 55835 | RNAseq | 0.8303 | 0.0000 | |
| SRP219564 | CENPJ | 55835 | RNAseq | 0.5491 | 0.1449 | |
| TCGA | CENPJ | 55835 | RNAseq | 0.4291 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by CENPJ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPJ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPJ | 55835 | 1 | 12 | 17 | |
| GSE20123 | CENPJ | 55835 | 1 | 11 | 18 | |
| GSE43470 | CENPJ | 55835 | 2 | 13 | 28 | |
| GSE46452 | CENPJ | 55835 | 0 | 33 | 26 | |
| GSE47630 | CENPJ | 55835 | 3 | 26 | 11 | |
| GSE54993 | CENPJ | 55835 | 11 | 2 | 57 | |
| GSE54994 | CENPJ | 55835 | 1 | 13 | 39 | |
| GSE60625 | CENPJ | 55835 | 0 | 3 | 8 | |
| GSE74703 | CENPJ | 55835 | 2 | 10 | 24 | |
| GSE74704 | CENPJ | 55835 | 0 | 9 | 11 | |
| TCGA | CENPJ | 55835 | 5 | 46 | 45 |
Total number of gains: 26; Total number of losses: 178; Total Number of normals: 284.
Somatic mutations of CENPJ:
Generating mutation plots.
Highly correlated genes for CENPJ:
Showing top 20/1215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPJ | NEDD1 | 0.735656 | 6 | 0 | 6 |
| CENPJ | MTBP | 0.729491 | 5 | 0 | 5 |
| CENPJ | CCDC14 | 0.723254 | 6 | 0 | 6 |
| CENPJ | LGALS8 | 0.714482 | 3 | 0 | 3 |
| CENPJ | WDR54 | 0.706878 | 5 | 0 | 5 |
| CENPJ | ZNF281 | 0.705912 | 6 | 0 | 6 |
| CENPJ | RACGAP1 | 0.704411 | 5 | 0 | 5 |
| CENPJ | MGAT2 | 0.69912 | 3 | 0 | 3 |
| CENPJ | FUS | 0.697668 | 7 | 0 | 6 |
| CENPJ | PTCD1 | 0.695022 | 3 | 0 | 3 |
| CENPJ | ZBTB26 | 0.694989 | 4 | 0 | 4 |
| CENPJ | DHX37 | 0.694968 | 4 | 0 | 4 |
| CENPJ | NDUFAF7 | 0.693278 | 5 | 0 | 5 |
| CENPJ | RAB34 | 0.692301 | 3 | 0 | 3 |
| CENPJ | SRSF6 | 0.691648 | 3 | 0 | 3 |
| CENPJ | MAP3K2 | 0.691402 | 6 | 0 | 5 |
| CENPJ | NADK | 0.691315 | 3 | 0 | 3 |
| CENPJ | SOCS4 | 0.689035 | 5 | 0 | 4 |
| CENPJ | FAM161A | 0.687463 | 6 | 0 | 5 |
| CENPJ | SMYD5 | 0.68654 | 6 | 0 | 6 |
For details and further investigation, click here
