| Full name: nei like DNA glycosylase 3 | Alias Symbol: FLJ10858|hFPG2|FPG2|hNEI3|ZGRF3 | ||
| Type: protein-coding gene | Cytoband: 4q34.3 | ||
| Entrez ID: 55247 | HGNC ID: HGNC:24573 | Ensembl Gene: ENSG00000109674 | OMIM ID: 608934 |
| Drug and gene relationship at DGIdb | |||
Expression of NEIL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEIL3 | 55247 | 219502_at | 0.9218 | 0.0225 | |
| GSE20347 | NEIL3 | 55247 | 219502_at | 0.6911 | 0.0001 | |
| GSE23400 | NEIL3 | 55247 | 219502_at | 0.3142 | 0.0000 | |
| GSE26886 | NEIL3 | 55247 | 219502_at | -0.1286 | 0.6159 | |
| GSE29001 | NEIL3 | 55247 | 219502_at | 0.8396 | 0.0031 | |
| GSE38129 | NEIL3 | 55247 | 219502_at | 0.9726 | 0.0000 | |
| GSE45670 | NEIL3 | 55247 | 219502_at | 0.8607 | 0.0010 | |
| GSE63941 | NEIL3 | 55247 | 219502_at | 2.3014 | 0.0170 | |
| GSE77861 | NEIL3 | 55247 | 219502_at | 0.2959 | 0.1609 | |
| SRP007169 | NEIL3 | 55247 | RNAseq | 1.0127 | 0.1238 | |
| SRP008496 | NEIL3 | 55247 | RNAseq | 0.2934 | 0.5279 | |
| SRP133303 | NEIL3 | 55247 | RNAseq | 1.1495 | 0.0001 | |
| SRP159526 | NEIL3 | 55247 | RNAseq | 0.8882 | 0.0165 | |
| SRP193095 | NEIL3 | 55247 | RNAseq | 0.4036 | 0.0652 | |
| SRP219564 | NEIL3 | 55247 | RNAseq | 0.3959 | 0.6316 | |
| TCGA | NEIL3 | 55247 | RNAseq | 1.7869 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NEIL3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NEIL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEIL3 | 55247 | 1 | 10 | 19 | |
| GSE20123 | NEIL3 | 55247 | 1 | 10 | 19 | |
| GSE43470 | NEIL3 | 55247 | 0 | 14 | 29 | |
| GSE46452 | NEIL3 | 55247 | 1 | 36 | 22 | |
| GSE47630 | NEIL3 | 55247 | 0 | 22 | 18 | |
| GSE54993 | NEIL3 | 55247 | 10 | 0 | 60 | |
| GSE54994 | NEIL3 | 55247 | 2 | 12 | 39 | |
| GSE60625 | NEIL3 | 55247 | 0 | 0 | 11 | |
| GSE74703 | NEIL3 | 55247 | 0 | 12 | 24 | |
| GSE74704 | NEIL3 | 55247 | 0 | 5 | 15 | |
| TCGA | NEIL3 | 55247 | 11 | 35 | 50 |
Total number of gains: 26; Total number of losses: 156; Total Number of normals: 306.
Somatic mutations of NEIL3:
Generating mutation plots.
Highly correlated genes for NEIL3:
Showing top 20/940 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEIL3 | XPR1 | 0.786184 | 3 | 0 | 3 |
| NEIL3 | KNSTRN | 0.761129 | 4 | 0 | 4 |
| NEIL3 | CDT1 | 0.739768 | 6 | 0 | 6 |
| NEIL3 | KIF18B | 0.73927 | 8 | 0 | 8 |
| NEIL3 | DCBLD1 | 0.734901 | 3 | 0 | 3 |
| NEIL3 | CD276 | 0.7341 | 3 | 0 | 3 |
| NEIL3 | CEP55 | 0.724303 | 9 | 0 | 9 |
| NEIL3 | MPLKIP | 0.718344 | 3 | 0 | 3 |
| NEIL3 | CENPF | 0.7165 | 8 | 0 | 8 |
| NEIL3 | HJURP | 0.715403 | 8 | 0 | 8 |
| NEIL3 | CCNF | 0.712893 | 7 | 0 | 7 |
| NEIL3 | CPNE2 | 0.709925 | 3 | 0 | 3 |
| NEIL3 | CCSAP | 0.709909 | 3 | 0 | 3 |
| NEIL3 | FOXM1 | 0.709824 | 9 | 0 | 8 |
| NEIL3 | CTHRC1 | 0.70877 | 3 | 0 | 3 |
| NEIL3 | KIF2C | 0.70714 | 8 | 0 | 8 |
| NEIL3 | PLK1 | 0.707001 | 7 | 0 | 7 |
| NEIL3 | HAUS8 | 0.70339 | 4 | 0 | 4 |
| NEIL3 | CDCA8 | 0.702791 | 8 | 0 | 7 |
| NEIL3 | MSANTD3 | 0.701509 | 3 | 0 | 3 |
For details and further investigation, click here
