| Full name: T-box transcription factor 15 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p12 | ||
| Entrez ID: 6913 | HGNC ID: HGNC:11594 | Ensembl Gene: ENSG00000092607 | OMIM ID: 604127 |
| Drug and gene relationship at DGIdb | |||
Expression of TBX15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBX15 | 6913 | 230438_at | 0.3512 | 0.2171 | |
| GSE26886 | TBX15 | 6913 | 230438_at | 1.0173 | 0.0000 | |
| GSE45670 | TBX15 | 6913 | 230438_at | 0.2920 | 0.0657 | |
| GSE53622 | TBX15 | 6913 | 67582 | 2.2798 | 0.0000 | |
| GSE53624 | TBX15 | 6913 | 67582 | 3.3675 | 0.0000 | |
| GSE63941 | TBX15 | 6913 | 230438_at | 0.1562 | 0.6742 | |
| GSE77861 | TBX15 | 6913 | 230438_at | 0.1526 | 0.2513 | |
| GSE97050 | TBX15 | 6913 | A_24_P128442 | 0.1761 | 0.4850 | |
| SRP064894 | TBX15 | 6913 | RNAseq | 4.2280 | 0.0000 | |
| SRP159526 | TBX15 | 6913 | RNAseq | 3.6327 | 0.0000 | |
| SRP219564 | TBX15 | 6913 | RNAseq | 3.2837 | 0.0001 | |
| TCGA | TBX15 | 6913 | RNAseq | 1.6477 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by TBX15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBX15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBX15 | 6913 | 2 | 6 | 22 | |
| GSE20123 | TBX15 | 6913 | 3 | 6 | 21 | |
| GSE43470 | TBX15 | 6913 | 1 | 3 | 39 | |
| GSE46452 | TBX15 | 6913 | 2 | 1 | 56 | |
| GSE47630 | TBX15 | 6913 | 10 | 4 | 26 | |
| GSE54993 | TBX15 | 6913 | 0 | 2 | 68 | |
| GSE54994 | TBX15 | 6913 | 12 | 1 | 40 | |
| GSE60625 | TBX15 | 6913 | 0 | 0 | 11 | |
| GSE74703 | TBX15 | 6913 | 1 | 3 | 32 | |
| GSE74704 | TBX15 | 6913 | 1 | 4 | 15 | |
| TCGA | TBX15 | 6913 | 17 | 26 | 53 |
Total number of gains: 49; Total number of losses: 56; Total Number of normals: 383.
Somatic mutations of TBX15:
Generating mutation plots.
Highly correlated genes for TBX15:
Showing top 20/976 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBX15 | COL1A1 | 0.71628 | 3 | 0 | 3 |
| TBX15 | FSTL3 | 0.701292 | 3 | 0 | 3 |
| TBX15 | PANK4 | 0.689324 | 3 | 0 | 3 |
| TBX15 | COL5A1 | 0.682801 | 4 | 0 | 3 |
| TBX15 | IL13RA2 | 0.682027 | 3 | 0 | 3 |
| TBX15 | CDK2AP2 | 0.680816 | 4 | 0 | 4 |
| TBX15 | MMP13 | 0.68078 | 4 | 0 | 3 |
| TBX15 | ZNF593 | 0.679837 | 3 | 0 | 3 |
| TBX15 | ITGA5 | 0.664478 | 4 | 0 | 4 |
| TBX15 | GIGYF1 | 0.662872 | 4 | 0 | 4 |
| TBX15 | USB1 | 0.659968 | 5 | 0 | 5 |
| TBX15 | POSTN | 0.659702 | 4 | 0 | 4 |
| TBX15 | BANF1 | 0.656967 | 5 | 0 | 5 |
| TBX15 | GTPBP3 | 0.656941 | 3 | 0 | 3 |
| TBX15 | BID | 0.654606 | 4 | 0 | 4 |
| TBX15 | MISP | 0.653293 | 5 | 0 | 4 |
| TBX15 | FCGR3A | 0.652639 | 3 | 0 | 3 |
| TBX15 | HDAC7 | 0.651978 | 4 | 0 | 4 |
| TBX15 | TMEM161A | 0.649995 | 4 | 0 | 4 |
| TBX15 | DTX3 | 0.648262 | 3 | 0 | 3 |
For details and further investigation, click here
