| Full name: UDP-glucose 6-dehydrogenase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p14 | ||
| Entrez ID: 7358 | HGNC ID: HGNC:12525 | Ensembl Gene: ENSG00000109814 | OMIM ID: 603370 |
| Drug and gene relationship at DGIdb | |||
Expression of UGDH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGDH | 7358 | 203343_at | 0.2661 | 0.6733 | |
| GSE20347 | UGDH | 7358 | 203343_at | -0.5427 | 0.0248 | |
| GSE23400 | UGDH | 7358 | 203343_at | -0.0823 | 0.4551 | |
| GSE26886 | UGDH | 7358 | 203343_at | -0.6718 | 0.0257 | |
| GSE29001 | UGDH | 7358 | 203343_at | -0.2522 | 0.4476 | |
| GSE38129 | UGDH | 7358 | 203343_at | -0.4347 | 0.0164 | |
| GSE45670 | UGDH | 7358 | 203343_at | -0.7147 | 0.0148 | |
| GSE53622 | UGDH | 7358 | 1222 | -0.3402 | 0.0012 | |
| GSE53624 | UGDH | 7358 | 1222 | -0.2882 | 0.0009 | |
| GSE63941 | UGDH | 7358 | 203343_at | -1.7173 | 0.0309 | |
| GSE77861 | UGDH | 7358 | 203343_at | -0.1411 | 0.8245 | |
| GSE97050 | UGDH | 7358 | A_33_P3396607 | -0.4237 | 0.2642 | |
| SRP007169 | UGDH | 7358 | RNAseq | 0.2514 | 0.6812 | |
| SRP008496 | UGDH | 7358 | RNAseq | 0.9912 | 0.0191 | |
| SRP064894 | UGDH | 7358 | RNAseq | 0.0270 | 0.9211 | |
| SRP133303 | UGDH | 7358 | RNAseq | -0.2807 | 0.2004 | |
| SRP159526 | UGDH | 7358 | RNAseq | 0.8637 | 0.0486 | |
| SRP193095 | UGDH | 7358 | RNAseq | -0.3244 | 0.1794 | |
| SRP219564 | UGDH | 7358 | RNAseq | 0.5203 | 0.3299 | |
| TCGA | UGDH | 7358 | RNAseq | -0.0949 | 0.2805 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UGDH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UGDH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGDH | 7358 | 0 | 16 | 14 | |
| GSE20123 | UGDH | 7358 | 0 | 16 | 14 | |
| GSE43470 | UGDH | 7358 | 0 | 15 | 28 | |
| GSE46452 | UGDH | 7358 | 1 | 36 | 22 | |
| GSE47630 | UGDH | 7358 | 1 | 19 | 20 | |
| GSE54993 | UGDH | 7358 | 8 | 0 | 62 | |
| GSE54994 | UGDH | 7358 | 3 | 10 | 40 | |
| GSE60625 | UGDH | 7358 | 0 | 0 | 11 | |
| GSE74703 | UGDH | 7358 | 0 | 12 | 24 | |
| GSE74704 | UGDH | 7358 | 0 | 9 | 11 | |
| TCGA | UGDH | 7358 | 10 | 45 | 41 |
Total number of gains: 23; Total number of losses: 178; Total Number of normals: 287.
Somatic mutations of UGDH:
Generating mutation plots.
Highly correlated genes for UGDH:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGDH | CEP70 | 0.687123 | 3 | 0 | 3 |
| UGDH | CCDC149 | 0.642444 | 3 | 0 | 3 |
| UGDH | PARD3 | 0.598566 | 4 | 0 | 3 |
| UGDH | MAP3K5 | 0.58298 | 4 | 0 | 3 |
| UGDH | CYP27A1 | 0.581497 | 3 | 0 | 3 |
| UGDH | SNX9 | 0.573149 | 3 | 0 | 3 |
| UGDH | EEPD1 | 0.573038 | 3 | 0 | 3 |
| UGDH | KCTD21 | 0.572737 | 3 | 0 | 3 |
| UGDH | HEATR5B | 0.567111 | 4 | 0 | 3 |
| UGDH | STRADB | 0.563116 | 5 | 0 | 3 |
| UGDH | POLDIP3 | 0.561974 | 3 | 0 | 3 |
| UGDH | SEMA6A | 0.555958 | 3 | 0 | 3 |
| UGDH | MAOA | 0.554553 | 8 | 0 | 5 |
| UGDH | ALDH3A1 | 0.551778 | 9 | 0 | 5 |
| UGDH | YTHDF3 | 0.547786 | 3 | 0 | 3 |
| UGDH | PTN | 0.54429 | 7 | 0 | 4 |
| UGDH | HECW2 | 0.544023 | 4 | 0 | 3 |
| UGDH | CNKSR3 | 0.538641 | 4 | 0 | 3 |
| UGDH | LRRN4CL | 0.537952 | 3 | 0 | 3 |
| UGDH | MEGF9 | 0.536392 | 10 | 0 | 5 |
For details and further investigation, click here
