| Full name: chitinase 3 like 2 | Alias Symbol: YKL-39|YKL39 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 1117 | HGNC ID: HGNC:1933 | Ensembl Gene: ENSG00000064886 | OMIM ID: 601526 |
| Drug and gene relationship at DGIdb | |||
Expression of CHI3L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHI3L2 | 1117 | 213060_s_at | 0.5499 | 0.6143 | |
| GSE20347 | CHI3L2 | 1117 | 213060_s_at | -0.0018 | 0.9944 | |
| GSE23400 | CHI3L2 | 1117 | 213060_s_at | -0.1332 | 0.0096 | |
| GSE26886 | CHI3L2 | 1117 | 213060_s_at | -0.3785 | 0.5259 | |
| GSE29001 | CHI3L2 | 1117 | 213060_s_at | -0.2547 | 0.2073 | |
| GSE38129 | CHI3L2 | 1117 | 213060_s_at | 0.0749 | 0.7745 | |
| GSE45670 | CHI3L2 | 1117 | 213060_s_at | 0.7272 | 0.0508 | |
| GSE53622 | CHI3L2 | 1117 | 66506 | 0.0822 | 0.8181 | |
| GSE53624 | CHI3L2 | 1117 | 66506 | -0.1410 | 0.6161 | |
| GSE63941 | CHI3L2 | 1117 | 213060_s_at | -1.5707 | 0.0002 | |
| GSE77861 | CHI3L2 | 1117 | 213060_s_at | 0.0208 | 0.9059 | |
| GSE97050 | CHI3L2 | 1117 | A_23_P12082 | 0.2950 | 0.3254 | |
| SRP133303 | CHI3L2 | 1117 | RNAseq | -0.6469 | 0.2227 | |
| SRP159526 | CHI3L2 | 1117 | RNAseq | 0.8608 | 0.3324 | |
| SRP219564 | CHI3L2 | 1117 | RNAseq | 1.5950 | 0.0942 | |
| TCGA | CHI3L2 | 1117 | RNAseq | 0.8173 | 0.0517 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CHI3L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHI3L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHI3L2 | 1117 | 0 | 11 | 19 | |
| GSE20123 | CHI3L2 | 1117 | 0 | 11 | 19 | |
| GSE43470 | CHI3L2 | 1117 | 0 | 8 | 35 | |
| GSE46452 | CHI3L2 | 1117 | 2 | 1 | 56 | |
| GSE47630 | CHI3L2 | 1117 | 9 | 5 | 26 | |
| GSE54993 | CHI3L2 | 1117 | 0 | 1 | 69 | |
| GSE54994 | CHI3L2 | 1117 | 7 | 4 | 42 | |
| GSE60625 | CHI3L2 | 1117 | 0 | 0 | 11 | |
| GSE74703 | CHI3L2 | 1117 | 0 | 7 | 29 | |
| GSE74704 | CHI3L2 | 1117 | 0 | 7 | 13 | |
| TCGA | CHI3L2 | 1117 | 7 | 27 | 62 |
Total number of gains: 25; Total number of losses: 82; Total Number of normals: 381.
Somatic mutations of CHI3L2:
Generating mutation plots.
Highly correlated genes for CHI3L2:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHI3L2 | KLK14 | 0.69871 | 3 | 0 | 3 |
| CHI3L2 | QPRT | 0.693708 | 3 | 0 | 3 |
| CHI3L2 | SLA2 | 0.685349 | 3 | 0 | 3 |
| CHI3L2 | OTUD4 | 0.672105 | 3 | 0 | 3 |
| CHI3L2 | ADAMTS7 | 0.666919 | 3 | 0 | 3 |
| CHI3L2 | MMP19 | 0.6576 | 4 | 0 | 3 |
| CHI3L2 | IGHMBP2 | 0.657547 | 4 | 0 | 3 |
| CHI3L2 | GJA3 | 0.648246 | 4 | 0 | 3 |
| CHI3L2 | KIR3DL3 | 0.646384 | 4 | 0 | 3 |
| CHI3L2 | SELL | 0.643895 | 5 | 0 | 5 |
| CHI3L2 | TSKS | 0.642061 | 3 | 0 | 3 |
| CHI3L2 | CA9 | 0.641137 | 3 | 0 | 3 |
| CHI3L2 | DNASE1 | 0.639627 | 3 | 0 | 3 |
| CHI3L2 | B3GALT1 | 0.638931 | 4 | 0 | 3 |
| CHI3L2 | MAPK8IP2 | 0.636389 | 4 | 0 | 4 |
| CHI3L2 | SCARF2 | 0.636179 | 3 | 0 | 3 |
| CHI3L2 | TCP10 | 0.631129 | 3 | 0 | 3 |
| CHI3L2 | PTPRCAP | 0.630208 | 5 | 0 | 4 |
| CHI3L2 | NGFR | 0.628553 | 3 | 0 | 3 |
| CHI3L2 | MAGEA8 | 0.628152 | 4 | 0 | 3 |
For details and further investigation, click here
