| Full name: carbohydrate sulfotransferase 14 | Alias Symbol: HD4ST|D4ST-1 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 113189 | HGNC ID: HGNC:24464 | Ensembl Gene: ENSG00000169105 | OMIM ID: 608429 |
| Drug and gene relationship at DGIdb | |||
Expression of CHST14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHST14 | 113189 | 226314_at | 0.2869 | 0.5342 | |
| GSE26886 | CHST14 | 113189 | 226314_at | 1.2218 | 0.0002 | |
| GSE45670 | CHST14 | 113189 | 226314_at | -0.0412 | 0.7745 | |
| GSE53622 | CHST14 | 113189 | 79315 | 0.7678 | 0.0000 | |
| GSE53624 | CHST14 | 113189 | 79315 | 0.7814 | 0.0000 | |
| GSE63941 | CHST14 | 113189 | 226314_at | -1.2764 | 0.0003 | |
| GSE77861 | CHST14 | 113189 | 226314_at | 0.0629 | 0.7545 | |
| GSE97050 | CHST14 | 113189 | A_24_P210637 | -0.1558 | 0.5287 | |
| SRP007169 | CHST14 | 113189 | RNAseq | 0.6580 | 0.2227 | |
| SRP008496 | CHST14 | 113189 | RNAseq | 1.1491 | 0.0015 | |
| SRP064894 | CHST14 | 113189 | RNAseq | 1.1720 | 0.0000 | |
| SRP133303 | CHST14 | 113189 | RNAseq | 0.6053 | 0.0032 | |
| SRP159526 | CHST14 | 113189 | RNAseq | 1.2483 | 0.0000 | |
| SRP193095 | CHST14 | 113189 | RNAseq | 0.8950 | 0.0000 | |
| SRP219564 | CHST14 | 113189 | RNAseq | 0.8462 | 0.0695 | |
| TCGA | CHST14 | 113189 | RNAseq | 0.2803 | 0.0003 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by CHST14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHST14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHST14 | 113189 | 4 | 5 | 21 | |
| GSE20123 | CHST14 | 113189 | 4 | 5 | 21 | |
| GSE43470 | CHST14 | 113189 | 4 | 6 | 33 | |
| GSE46452 | CHST14 | 113189 | 3 | 7 | 49 | |
| GSE47630 | CHST14 | 113189 | 8 | 11 | 21 | |
| GSE54993 | CHST14 | 113189 | 4 | 6 | 60 | |
| GSE54994 | CHST14 | 113189 | 5 | 7 | 41 | |
| GSE60625 | CHST14 | 113189 | 4 | 0 | 7 | |
| GSE74703 | CHST14 | 113189 | 4 | 5 | 27 | |
| GSE74704 | CHST14 | 113189 | 3 | 3 | 14 | |
| TCGA | CHST14 | 113189 | 11 | 18 | 67 |
Total number of gains: 54; Total number of losses: 73; Total Number of normals: 361.
Somatic mutations of CHST14:
Generating mutation plots.
Highly correlated genes for CHST14:
Showing top 20/404 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHST14 | SH3RF3 | 0.734304 | 3 | 0 | 3 |
| CHST14 | PAMR1 | 0.73253 | 3 | 0 | 3 |
| CHST14 | CPB2 | 0.727489 | 3 | 0 | 3 |
| CHST14 | RPS19BP1 | 0.724058 | 3 | 0 | 3 |
| CHST14 | FAM171B | 0.715415 | 4 | 0 | 4 |
| CHST14 | DEXI | 0.711628 | 4 | 0 | 4 |
| CHST14 | TP53TG1 | 0.703979 | 3 | 0 | 3 |
| CHST14 | POMGNT1 | 0.700667 | 4 | 0 | 4 |
| CHST14 | FNDC3B | 0.697846 | 3 | 0 | 3 |
| CHST14 | LETM2 | 0.694937 | 3 | 0 | 3 |
| CHST14 | PTK2 | 0.694538 | 3 | 0 | 3 |
| CHST14 | HNRNPLL | 0.692357 | 3 | 0 | 3 |
| CHST14 | LRPAP1 | 0.692181 | 3 | 0 | 3 |
| CHST14 | ASB7 | 0.691771 | 3 | 0 | 3 |
| CHST14 | HEY1 | 0.690605 | 5 | 0 | 4 |
| CHST14 | DOCK4 | 0.686978 | 3 | 0 | 3 |
| CHST14 | RCN2 | 0.67717 | 4 | 0 | 3 |
| CHST14 | MLXIP | 0.676783 | 3 | 0 | 3 |
| CHST14 | PFN2 | 0.673252 | 3 | 0 | 3 |
| CHST14 | TMEM263 | 0.671952 | 4 | 0 | 4 |
For details and further investigation, click here
