| Full name: chemokine like factor | Alias Symbol: UCK-1|CKLF3|CKLF4|HSPC224|C32 | ||
| Type: protein-coding gene | Cytoband: 16q21 | ||
| Entrez ID: 51192 | HGNC ID: HGNC:13253 | Ensembl Gene: ENSG00000217555 | OMIM ID: 616074 |
| Drug and gene relationship at DGIdb | |||
Expression of CKLF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CKLF | 51192 | 221058_s_at | 0.8091 | 0.0266 | |
| GSE20347 | CKLF | 51192 | 221058_s_at | 0.4721 | 0.0122 | |
| GSE23400 | CKLF | 51192 | 221058_s_at | 0.3724 | 0.0000 | |
| GSE26886 | CKLF | 51192 | 223451_s_at | 0.0229 | 0.9456 | |
| GSE29001 | CKLF | 51192 | 221058_s_at | 0.5490 | 0.0115 | |
| GSE38129 | CKLF | 51192 | 221058_s_at | 0.5388 | 0.0001 | |
| GSE45670 | CKLF | 51192 | 221058_s_at | 0.3075 | 0.0867 | |
| GSE53622 | CKLF | 51192 | 91872 | 0.6315 | 0.0002 | |
| GSE53624 | CKLF | 51192 | 91872 | 0.5684 | 0.0484 | |
| GSE63941 | CKLF | 51192 | 221058_s_at | 0.7011 | 0.3903 | |
| GSE77861 | CKLF | 51192 | 223451_s_at | -0.0576 | 0.8085 | |
| GSE97050 | CKLF | 51192 | A_23_P118061 | 0.7215 | 0.1386 | |
| SRP007169 | CKLF | 51192 | RNAseq | 0.8708 | 0.2722 | |
| SRP064894 | CKLF | 51192 | RNAseq | 0.8202 | 0.0033 | |
| SRP133303 | CKLF | 51192 | RNAseq | 0.7025 | 0.0000 | |
| SRP159526 | CKLF | 51192 | RNAseq | 0.6477 | 0.0354 | |
| SRP193095 | CKLF | 51192 | RNAseq | 0.3232 | 0.0239 | |
| SRP219564 | CKLF | 51192 | RNAseq | 0.1806 | 0.6348 | |
| TCGA | CKLF | 51192 | RNAseq | 0.5260 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CKLF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CKLF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CKLF | 51192 | 8 | 2 | 20 | |
| GSE20123 | CKLF | 51192 | 8 | 2 | 20 | |
| GSE43470 | CKLF | 51192 | 1 | 8 | 34 | |
| GSE46452 | CKLF | 51192 | 38 | 1 | 20 | |
| GSE47630 | CKLF | 51192 | 10 | 8 | 22 | |
| GSE54993 | CKLF | 51192 | 2 | 4 | 64 | |
| GSE54994 | CKLF | 51192 | 8 | 10 | 35 | |
| GSE60625 | CKLF | 51192 | 4 | 0 | 7 | |
| GSE74703 | CKLF | 51192 | 1 | 5 | 30 | |
| GSE74704 | CKLF | 51192 | 5 | 1 | 14 | |
| TCGA | CKLF | 51192 | 30 | 11 | 55 |
Total number of gains: 115; Total number of losses: 52; Total Number of normals: 321.
Somatic mutations of CKLF:
Generating mutation plots.
Highly correlated genes for CKLF:
Showing top 20/955 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CKLF | CENPBD1 | 0.759439 | 3 | 0 | 3 |
| CKLF | VPS16 | 0.724806 | 3 | 0 | 3 |
| CKLF | ATRN | 0.702573 | 4 | 0 | 3 |
| CKLF | TRUB1 | 0.699813 | 5 | 0 | 5 |
| CKLF | TMEM138 | 0.698475 | 4 | 0 | 4 |
| CKLF | SFR1 | 0.69729 | 4 | 0 | 4 |
| CKLF | TOP3A | 0.685807 | 3 | 0 | 3 |
| CKLF | KDM1A | 0.682169 | 6 | 0 | 6 |
| CKLF | NUDT5 | 0.679608 | 4 | 0 | 3 |
| CKLF | CISD2 | 0.673594 | 3 | 0 | 3 |
| CKLF | ANXA7 | 0.672962 | 3 | 0 | 3 |
| CKLF | EMC1 | 0.671654 | 5 | 0 | 4 |
| CKLF | PSTPIP2 | 0.670983 | 4 | 0 | 4 |
| CKLF | PSKH1 | 0.669841 | 3 | 0 | 3 |
| CKLF | TRA2B | 0.669534 | 4 | 0 | 4 |
| CKLF | DDX55 | 0.66904 | 3 | 0 | 3 |
| CKLF | SLC5A12 | 0.66739 | 3 | 0 | 3 |
| CKLF | RPRD1B | 0.66581 | 5 | 0 | 4 |
| CKLF | SPATA2 | 0.665292 | 3 | 0 | 3 |
| CKLF | UBE2J2 | 0.664804 | 3 | 0 | 3 |
For details and further investigation, click here
