| Full name: centromere protein N | Alias Symbol: FLJ13607|FLJ22660|BM039 | ||
| Type: protein-coding gene | Cytoband: 16q23.2 | ||
| Entrez ID: 55839 | HGNC ID: HGNC:30873 | Ensembl Gene: ENSG00000166451 | OMIM ID: 611509 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CENPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPN | 55839 | 228559_at | 1.7928 | 0.0148 | |
| GSE20347 | CENPN | 55839 | 219555_s_at | 1.8049 | 0.0000 | |
| GSE23400 | CENPN | 55839 | 219555_s_at | 0.9100 | 0.0000 | |
| GSE26886 | CENPN | 55839 | 219555_s_at | 1.2018 | 0.0008 | |
| GSE29001 | CENPN | 55839 | 219555_s_at | 1.3734 | 0.0101 | |
| GSE38129 | CENPN | 55839 | 219555_s_at | 2.2608 | 0.0000 | |
| GSE45670 | CENPN | 55839 | 219555_s_at | 1.6771 | 0.0000 | |
| GSE53622 | CENPN | 55839 | 40847 | 1.5067 | 0.0000 | |
| GSE53624 | CENPN | 55839 | 40847 | 1.9051 | 0.0000 | |
| GSE63941 | CENPN | 55839 | 219555_s_at | 2.5782 | 0.0002 | |
| GSE77861 | CENPN | 55839 | 219555_s_at | 1.1027 | 0.0076 | |
| GSE97050 | CENPN | 55839 | A_23_P88740 | 1.1099 | 0.1368 | |
| SRP007169 | CENPN | 55839 | RNAseq | 1.5519 | 0.0000 | |
| SRP008496 | CENPN | 55839 | RNAseq | 1.2992 | 0.0005 | |
| SRP064894 | CENPN | 55839 | RNAseq | 1.0930 | 0.0000 | |
| SRP133303 | CENPN | 55839 | RNAseq | 1.2915 | 0.0000 | |
| SRP159526 | CENPN | 55839 | RNAseq | 1.3765 | 0.0029 | |
| SRP193095 | CENPN | 55839 | RNAseq | 0.8447 | 0.0000 | |
| SRP219564 | CENPN | 55839 | RNAseq | 1.2518 | 0.0330 | |
| TCGA | CENPN | 55839 | RNAseq | 0.4768 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by CENPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPN | 55839 | 5 | 2 | 23 | |
| GSE20123 | CENPN | 55839 | 5 | 2 | 23 | |
| GSE43470 | CENPN | 55839 | 2 | 8 | 33 | |
| GSE46452 | CENPN | 55839 | 37 | 2 | 20 | |
| GSE47630 | CENPN | 55839 | 11 | 8 | 21 | |
| GSE54993 | CENPN | 55839 | 2 | 4 | 64 | |
| GSE54994 | CENPN | 55839 | 7 | 10 | 36 | |
| GSE60625 | CENPN | 55839 | 4 | 0 | 7 | |
| GSE74703 | CENPN | 55839 | 2 | 6 | 28 | |
| GSE74704 | CENPN | 55839 | 3 | 2 | 15 | |
| TCGA | CENPN | 55839 | 24 | 16 | 56 |
Total number of gains: 102; Total number of losses: 60; Total Number of normals: 326.
Somatic mutations of CENPN:
Generating mutation plots.
Highly correlated genes for CENPN:
Showing top 20/1891 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPN | BUB1B | 0.848829 | 9 | 0 | 9 |
| CENPN | CCNB2 | 0.836929 | 12 | 0 | 12 |
| CENPN | MTFR2 | 0.835572 | 7 | 0 | 7 |
| CENPN | NCAPH | 0.833024 | 9 | 0 | 9 |
| CENPN | CDK1 | 0.831607 | 12 | 0 | 12 |
| CENPN | CDKN3 | 0.830427 | 13 | 0 | 13 |
| CENPN | CDC20 | 0.829506 | 11 | 0 | 11 |
| CENPN | CENPF | 0.828605 | 12 | 0 | 12 |
| CENPN | GINS2 | 0.825242 | 12 | 0 | 12 |
| CENPN | UBE2C | 0.822175 | 13 | 0 | 12 |
| CENPN | UBE2T | 0.819614 | 9 | 0 | 9 |
| CENPN | GINS1 | 0.817009 | 12 | 0 | 12 |
| CENPN | KIF20A | 0.816645 | 12 | 0 | 12 |
| CENPN | FOXM1 | 0.815976 | 12 | 0 | 12 |
| CENPN | TTK | 0.815667 | 12 | 0 | 12 |
| CENPN | AURKB | 0.815658 | 13 | 0 | 12 |
| CENPN | ASPM | 0.815545 | 12 | 0 | 12 |
| CENPN | CEP55 | 0.814187 | 13 | 0 | 13 |
| CENPN | MYBL2 | 0.813962 | 12 | 0 | 12 |
| CENPN | RAD51 | 0.813431 | 11 | 0 | 11 |
For details and further investigation, click here
