| Full name: cyclic nucleotide gated channel subunit alpha 4 | Alias Symbol: OCNC2|OCNCb|CNG5 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 1262 | HGNC ID: HGNC:2152 | Ensembl Gene: ENSG00000132259 | OMIM ID: 609472 |
| Drug and gene relationship at DGIdb | |||
CNGA4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway | |
| hsa04740 | Olfactory transduction |
Expression of CNGA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNGA4 | 1262 | 1562273_at | -0.2180 | 0.3018 | |
| GSE26886 | CNGA4 | 1262 | 1562273_at | 0.1071 | 0.4687 | |
| GSE45670 | CNGA4 | 1262 | 1562273_at | 0.1384 | 0.1633 | |
| GSE53622 | CNGA4 | 1262 | 110176 | 0.0488 | 0.4545 | |
| GSE53624 | CNGA4 | 1262 | 110176 | 0.1145 | 0.0472 | |
| GSE63941 | CNGA4 | 1262 | 1562273_at | 0.1821 | 0.1902 | |
| GSE77861 | CNGA4 | 1262 | 1562273_at | -0.0877 | 0.3496 | |
| GSE97050 | CNGA4 | 1262 | A_23_P2006 | -0.1985 | 0.4794 | |
| TCGA | CNGA4 | 1262 | RNAseq | -0.2846 | 0.4943 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNGA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNGA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNGA4 | 1262 | 1 | 11 | 18 | |
| GSE20123 | CNGA4 | 1262 | 1 | 11 | 18 | |
| GSE43470 | CNGA4 | 1262 | 1 | 8 | 34 | |
| GSE46452 | CNGA4 | 1262 | 7 | 8 | 44 | |
| GSE47630 | CNGA4 | 1262 | 2 | 12 | 26 | |
| GSE54993 | CNGA4 | 1262 | 3 | 1 | 66 | |
| GSE54994 | CNGA4 | 1262 | 2 | 12 | 39 | |
| GSE60625 | CNGA4 | 1262 | 0 | 0 | 11 | |
| GSE74703 | CNGA4 | 1262 | 1 | 6 | 29 | |
| GSE74704 | CNGA4 | 1262 | 0 | 8 | 12 | |
| TCGA | CNGA4 | 1262 | 9 | 39 | 48 |
Total number of gains: 27; Total number of losses: 116; Total Number of normals: 345.
Somatic mutations of CNGA4:
Generating mutation plots.
Highly correlated genes for CNGA4:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNGA4 | CASP12 | 0.720098 | 3 | 0 | 3 |
| CNGA4 | KCNK9 | 0.71827 | 3 | 0 | 3 |
| CNGA4 | C9orf24 | 0.70725 | 3 | 0 | 3 |
| CNGA4 | ADAP1 | 0.696883 | 3 | 0 | 3 |
| CNGA4 | FAM189A2 | 0.686306 | 3 | 0 | 3 |
| CNGA4 | NRG2 | 0.676122 | 3 | 0 | 3 |
| CNGA4 | NNAT | 0.660428 | 3 | 0 | 3 |
| CNGA4 | CBLN1 | 0.659634 | 3 | 0 | 3 |
| CNGA4 | THPO | 0.645699 | 5 | 0 | 3 |
| CNGA4 | KCNH2 | 0.636029 | 3 | 0 | 3 |
| CNGA4 | ACBD4 | 0.629668 | 4 | 0 | 3 |
| CNGA4 | NACAD | 0.622789 | 4 | 0 | 3 |
| CNGA4 | CLNK | 0.619891 | 3 | 0 | 3 |
| CNGA4 | RGS11 | 0.619339 | 3 | 0 | 3 |
| CNGA4 | TSHB | 0.602444 | 3 | 0 | 3 |
| CNGA4 | TEKT2 | 0.600968 | 3 | 0 | 3 |
| CNGA4 | RGR | 0.594888 | 3 | 0 | 3 |
| CNGA4 | ADAMTS19 | 0.59403 | 3 | 0 | 3 |
| CNGA4 | ITGB1BP2 | 0.592974 | 4 | 0 | 3 |
| CNGA4 | HTR3A | 0.59064 | 4 | 0 | 3 |
For details and further investigation, click here
