| Full name: contactin associated protein like 2 | Alias Symbol: Caspr2|KIAA0868|NRXN4 | ||
| Type: protein-coding gene | Cytoband: 7q35-q36.1 | ||
| Entrez ID: 26047 | HGNC ID: HGNC:13830 | Ensembl Gene: ENSG00000174469 | OMIM ID: 604569 |
| Drug and gene relationship at DGIdb | |||
Expression of CNTNAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTNAP2 | 26047 | 219300_s_at | 0.8944 | 0.4794 | |
| GSE20347 | CNTNAP2 | 26047 | 219300_s_at | 1.2154 | 0.0152 | |
| GSE23400 | CNTNAP2 | 26047 | 215145_s_at | 0.0845 | 0.1241 | |
| GSE26886 | CNTNAP2 | 26047 | 219301_s_at | 0.9008 | 0.0449 | |
| GSE29001 | CNTNAP2 | 26047 | 219301_s_at | 1.7065 | 0.0016 | |
| GSE38129 | CNTNAP2 | 26047 | 219300_s_at | 1.1119 | 0.0018 | |
| GSE45670 | CNTNAP2 | 26047 | 219300_s_at | 1.0347 | 0.0032 | |
| GSE53622 | CNTNAP2 | 26047 | 14405 | 1.3198 | 0.0002 | |
| GSE53624 | CNTNAP2 | 26047 | 14405 | 1.7628 | 0.0000 | |
| GSE63941 | CNTNAP2 | 26047 | 219300_s_at | 1.4843 | 0.1818 | |
| GSE77861 | CNTNAP2 | 26047 | 219301_s_at | 0.5748 | 0.0971 | |
| GSE97050 | CNTNAP2 | 26047 | A_33_P3367196 | -0.0696 | 0.9323 | |
| SRP007169 | CNTNAP2 | 26047 | RNAseq | 5.3575 | 0.0000 | |
| SRP133303 | CNTNAP2 | 26047 | RNAseq | 2.5010 | 0.0002 | |
| SRP159526 | CNTNAP2 | 26047 | RNAseq | 3.7673 | 0.0000 | |
| SRP193095 | CNTNAP2 | 26047 | RNAseq | 2.3988 | 0.0000 | |
| SRP219564 | CNTNAP2 | 26047 | RNAseq | 1.8727 | 0.0816 | |
| TCGA | CNTNAP2 | 26047 | RNAseq | 0.5060 | 0.1753 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by CNTNAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTNAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTNAP2 | 26047 | 3 | 4 | 23 | |
| GSE20123 | CNTNAP2 | 26047 | 3 | 4 | 23 | |
| GSE43470 | CNTNAP2 | 26047 | 2 | 6 | 35 | |
| GSE46452 | CNTNAP2 | 26047 | 7 | 2 | 50 | |
| GSE47630 | CNTNAP2 | 26047 | 6 | 8 | 26 | |
| GSE54993 | CNTNAP2 | 26047 | 3 | 4 | 63 | |
| GSE54994 | CNTNAP2 | 26047 | 5 | 8 | 40 | |
| GSE60625 | CNTNAP2 | 26047 | 0 | 0 | 11 | |
| GSE74703 | CNTNAP2 | 26047 | 2 | 5 | 29 | |
| GSE74704 | CNTNAP2 | 26047 | 1 | 4 | 15 | |
| TCGA | CNTNAP2 | 26047 | 24 | 31 | 41 |
Total number of gains: 56; Total number of losses: 76; Total Number of normals: 356.
Somatic mutations of CNTNAP2:
Generating mutation plots.
Highly correlated genes for CNTNAP2:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTNAP2 | COPA | 0.720592 | 3 | 0 | 3 |
| CNTNAP2 | CHCHD2 | 0.705106 | 3 | 0 | 3 |
| CNTNAP2 | PPP6R3 | 0.69099 | 3 | 0 | 3 |
| CNTNAP2 | UBQLN4 | 0.689357 | 3 | 0 | 3 |
| CNTNAP2 | SSR3 | 0.678549 | 4 | 0 | 4 |
| CNTNAP2 | RNASEH1 | 0.67808 | 4 | 0 | 4 |
| CNTNAP2 | DRG1 | 0.67679 | 3 | 0 | 3 |
| CNTNAP2 | SMCHD1 | 0.674061 | 3 | 0 | 3 |
| CNTNAP2 | C14orf119 | 0.671707 | 4 | 0 | 4 |
| CNTNAP2 | OSBPL6 | 0.671389 | 3 | 0 | 3 |
| CNTNAP2 | XPO4 | 0.669378 | 3 | 0 | 3 |
| CNTNAP2 | CHD3 | 0.667423 | 3 | 0 | 3 |
| CNTNAP2 | RIMKLB | 0.663851 | 3 | 0 | 3 |
| CNTNAP2 | BABAM1 | 0.663446 | 3 | 0 | 3 |
| CNTNAP2 | L3HYPDH | 0.663427 | 4 | 0 | 3 |
| CNTNAP2 | PIGZ | 0.663284 | 3 | 0 | 3 |
| CNTNAP2 | ZNF114 | 0.662886 | 3 | 0 | 3 |
| CNTNAP2 | CEBPZ | 0.6601 | 4 | 0 | 4 |
| CNTNAP2 | LRP5L | 0.658352 | 4 | 0 | 3 |
| CNTNAP2 | RAB2B | 0.650386 | 4 | 0 | 4 |
For details and further investigation, click here
