| Full name: olfactory receptor family 51 subfamily E member 1 | Alias Symbol: GPR136 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 143503 | HGNC ID: HGNC:15194 | Ensembl Gene: ENSG00000180785 | OMIM ID: 611267 |
| Drug and gene relationship at DGIdb | |||
OR51E1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR51E1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR51E1 | 143503 | 229768_at | 0.3280 | 0.3490 | |
| GSE26886 | OR51E1 | 143503 | 229768_at | -0.0714 | 0.6673 | |
| GSE45670 | OR51E1 | 143503 | 229768_at | 0.6542 | 0.0069 | |
| GSE53622 | OR51E1 | 143503 | 149672 | 1.2499 | 0.0000 | |
| GSE53624 | OR51E1 | 143503 | 126475 | 1.3098 | 0.0000 | |
| GSE63941 | OR51E1 | 143503 | 229768_at | 0.1087 | 0.5067 | |
| GSE77861 | OR51E1 | 143503 | 229768_at | -0.0181 | 0.9461 | |
| SRP133303 | OR51E1 | 143503 | RNAseq | 1.6784 | 0.0000 | |
| SRP159526 | OR51E1 | 143503 | RNAseq | 1.7888 | 0.0028 | |
| SRP219564 | OR51E1 | 143503 | RNAseq | 1.4787 | 0.0428 | |
| TCGA | OR51E1 | 143503 | RNAseq | -0.1503 | 0.5809 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by OR51E1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR51E1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR51E1 | 143503 | 1 | 11 | 18 | |
| GSE20123 | OR51E1 | 143503 | 1 | 11 | 18 | |
| GSE43470 | OR51E1 | 143503 | 1 | 8 | 34 | |
| GSE46452 | OR51E1 | 143503 | 7 | 8 | 44 | |
| GSE47630 | OR51E1 | 143503 | 3 | 13 | 24 | |
| GSE54993 | OR51E1 | 143503 | 3 | 1 | 66 | |
| GSE54994 | OR51E1 | 143503 | 1 | 13 | 39 | |
| GSE60625 | OR51E1 | 143503 | 0 | 0 | 11 | |
| GSE74703 | OR51E1 | 143503 | 1 | 6 | 29 | |
| GSE74704 | OR51E1 | 143503 | 0 | 8 | 12 | |
| TCGA | OR51E1 | 143503 | 8 | 39 | 49 |
Total number of gains: 26; Total number of losses: 118; Total Number of normals: 344.
Somatic mutations of OR51E1:
Generating mutation plots.
Highly correlated genes for OR51E1:
Showing top 20/360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR51E1 | PLD3 | 0.734134 | 3 | 0 | 3 |
| OR51E1 | COA6 | 0.700234 | 3 | 0 | 3 |
| OR51E1 | ZNF281 | 0.677398 | 3 | 0 | 3 |
| OR51E1 | RRP7A | 0.674627 | 4 | 0 | 4 |
| OR51E1 | THY1 | 0.66705 | 4 | 0 | 4 |
| OR51E1 | SIGLEC15 | 0.664591 | 3 | 0 | 3 |
| OR51E1 | SIVA1 | 0.663987 | 4 | 0 | 4 |
| OR51E1 | GTF2E1 | 0.663096 | 3 | 0 | 3 |
| OR51E1 | TXNRD1 | 0.659757 | 4 | 0 | 3 |
| OR51E1 | ADAMTS12 | 0.658333 | 4 | 0 | 4 |
| OR51E1 | FARP1 | 0.65799 | 4 | 0 | 4 |
| OR51E1 | COL3A1 | 0.657011 | 3 | 0 | 3 |
| OR51E1 | ANGPT2 | 0.656319 | 3 | 0 | 3 |
| OR51E1 | STARD7 | 0.653685 | 3 | 0 | 3 |
| OR51E1 | ADAMTS6 | 0.650003 | 4 | 0 | 4 |
| OR51E1 | IGFBP3 | 0.646867 | 4 | 0 | 4 |
| OR51E1 | CDH11 | 0.6463 | 4 | 0 | 4 |
| OR51E1 | LRR1 | 0.646239 | 3 | 0 | 3 |
| OR51E1 | TBC1D31 | 0.644419 | 3 | 0 | 3 |
| OR51E1 | ALG3 | 0.642954 | 3 | 0 | 3 |
For details and further investigation, click here
