| Full name: trans-2,3-enoyl-CoA reductase | Alias Symbol: TER|MRT14 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 9524 | HGNC ID: HGNC:4551 | Ensembl Gene: ENSG00000099797 | OMIM ID: 610057 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TECR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TECR | 9524 | 208336_s_at | -0.6893 | 0.2385 | |
| GSE20347 | TECR | 9524 | 208336_s_at | -1.5870 | 0.0000 | |
| GSE23400 | TECR | 9524 | 208336_s_at | -1.1142 | 0.0000 | |
| GSE26886 | TECR | 9524 | 208336_s_at | -1.1455 | 0.0000 | |
| GSE29001 | TECR | 9524 | 208336_s_at | -1.4353 | 0.0091 | |
| GSE38129 | TECR | 9524 | 208336_s_at | -0.8814 | 0.0013 | |
| GSE45670 | TECR | 9524 | 208336_s_at | -0.4152 | 0.0391 | |
| GSE53622 | TECR | 9524 | 132558 | -1.1199 | 0.0000 | |
| GSE53624 | TECR | 9524 | 132558 | -1.2110 | 0.0000 | |
| GSE63941 | TECR | 9524 | 208336_s_at | 2.4509 | 0.0001 | |
| GSE77861 | TECR | 9524 | 208336_s_at | -0.8391 | 0.0121 | |
| GSE97050 | TECR | 9524 | A_33_P3372466 | -0.2204 | 0.7696 | |
| SRP007169 | TECR | 9524 | RNAseq | -2.5922 | 0.0000 | |
| SRP008496 | TECR | 9524 | RNAseq | -2.3320 | 0.0000 | |
| SRP064894 | TECR | 9524 | RNAseq | -0.9321 | 0.0085 | |
| SRP133303 | TECR | 9524 | RNAseq | -1.4105 | 0.0000 | |
| SRP159526 | TECR | 9524 | RNAseq | -1.2807 | 0.0000 | |
| SRP193095 | TECR | 9524 | RNAseq | -1.2558 | 0.0000 | |
| SRP219564 | TECR | 9524 | RNAseq | -0.3192 | 0.6440 | |
| TCGA | TECR | 9524 | RNAseq | 0.2104 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by TECR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TECR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TECR | 9524 | 4 | 2 | 24 | |
| GSE20123 | TECR | 9524 | 3 | 1 | 26 | |
| GSE43470 | TECR | 9524 | 2 | 6 | 35 | |
| GSE46452 | TECR | 9524 | 47 | 1 | 11 | |
| GSE47630 | TECR | 9524 | 4 | 7 | 29 | |
| GSE54993 | TECR | 9524 | 15 | 4 | 51 | |
| GSE54994 | TECR | 9524 | 6 | 13 | 34 | |
| GSE60625 | TECR | 9524 | 9 | 0 | 2 | |
| GSE74703 | TECR | 9524 | 2 | 4 | 30 | |
| GSE74704 | TECR | 9524 | 0 | 1 | 19 | |
| TCGA | TECR | 9524 | 18 | 11 | 67 |
Total number of gains: 110; Total number of losses: 50; Total Number of normals: 328.
Somatic mutations of TECR:
Generating mutation plots.
Highly correlated genes for TECR:
Showing top 20/1188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TECR | EPHA1 | 0.842017 | 11 | 0 | 11 |
| TECR | TOM1 | 0.839675 | 10 | 0 | 10 |
| TECR | SH3GL1 | 0.837447 | 10 | 0 | 10 |
| TECR | EVPL | 0.837408 | 12 | 0 | 12 |
| TECR | NAGK | 0.821406 | 10 | 0 | 10 |
| TECR | TMEM154 | 0.812376 | 7 | 0 | 7 |
| TECR | RAB25 | 0.802105 | 12 | 0 | 10 |
| TECR | EPS8L2 | 0.800038 | 11 | 0 | 11 |
| TECR | RAET1E | 0.798337 | 7 | 0 | 7 |
| TECR | BNIPL | 0.796609 | 7 | 0 | 7 |
| TECR | MPZL3 | 0.793624 | 7 | 0 | 7 |
| TECR | CYSRT1 | 0.793145 | 6 | 0 | 6 |
| TECR | DEGS2 | 0.789848 | 7 | 0 | 7 |
| TECR | MGST2 | 0.787529 | 10 | 0 | 10 |
| TECR | ASPG | 0.786017 | 5 | 0 | 5 |
| TECR | VSIG10L | 0.786012 | 7 | 0 | 7 |
| TECR | CHP1 | 0.785756 | 10 | 0 | 10 |
| TECR | NEBL | 0.782037 | 11 | 0 | 11 |
| TECR | SPINK7 | 0.781107 | 7 | 0 | 7 |
| TECR | DHRS1 | 0.780551 | 11 | 0 | 11 |
For details and further investigation, click here
