| Full name: component of oligomeric golgi complex 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p12.2 | ||
| Entrez ID: 91949 | HGNC ID: HGNC:18622 | Ensembl Gene: ENSG00000168434 | OMIM ID: 606978 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG7 | 91949 | 213190_at | 0.0352 | 0.9603 | |
| GSE20347 | COG7 | 91949 | 213190_at | 0.0116 | 0.9576 | |
| GSE23400 | COG7 | 91949 | 213190_at | 0.0163 | 0.8334 | |
| GSE26886 | COG7 | 91949 | 213190_at | -0.0377 | 0.8726 | |
| GSE29001 | COG7 | 91949 | 213190_at | 0.0804 | 0.7609 | |
| GSE38129 | COG7 | 91949 | 213190_at | 0.1119 | 0.4365 | |
| GSE45670 | COG7 | 91949 | 213190_at | -0.0985 | 0.4234 | |
| GSE53622 | COG7 | 91949 | 15927 | 0.2248 | 0.0001 | |
| GSE53624 | COG7 | 91949 | 15927 | 0.2162 | 0.0028 | |
| GSE63941 | COG7 | 91949 | 213190_at | 1.5635 | 0.0010 | |
| GSE77861 | COG7 | 91949 | 213190_at | 0.0667 | 0.7616 | |
| GSE97050 | COG7 | 91949 | A_23_P329361 | 0.1529 | 0.7047 | |
| SRP007169 | COG7 | 91949 | RNAseq | -0.1501 | 0.6530 | |
| SRP008496 | COG7 | 91949 | RNAseq | -0.0682 | 0.7743 | |
| SRP064894 | COG7 | 91949 | RNAseq | 0.0570 | 0.7179 | |
| SRP133303 | COG7 | 91949 | RNAseq | 0.1823 | 0.2866 | |
| SRP159526 | COG7 | 91949 | RNAseq | 0.3830 | 0.0570 | |
| SRP193095 | COG7 | 91949 | RNAseq | 0.0722 | 0.4770 | |
| SRP219564 | COG7 | 91949 | RNAseq | 0.0690 | 0.8095 | |
| TCGA | COG7 | 91949 | RNAseq | -0.0708 | 0.1626 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by COG7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG7 | 91949 | 6 | 4 | 20 | |
| GSE20123 | COG7 | 91949 | 6 | 3 | 21 | |
| GSE43470 | COG7 | 91949 | 3 | 3 | 37 | |
| GSE46452 | COG7 | 91949 | 38 | 1 | 20 | |
| GSE47630 | COG7 | 91949 | 11 | 6 | 23 | |
| GSE54993 | COG7 | 91949 | 3 | 5 | 62 | |
| GSE54994 | COG7 | 91949 | 4 | 9 | 40 | |
| GSE60625 | COG7 | 91949 | 4 | 0 | 7 | |
| GSE74703 | COG7 | 91949 | 3 | 2 | 31 | |
| GSE74704 | COG7 | 91949 | 3 | 1 | 16 | |
| TCGA | COG7 | 91949 | 19 | 13 | 64 |
Total number of gains: 100; Total number of losses: 47; Total Number of normals: 341.
Somatic mutations of COG7:
Generating mutation plots.
Highly correlated genes for COG7:
Showing top 20/260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG7 | COPE | 0.72972 | 3 | 0 | 3 |
| COG7 | SYAP1 | 0.709464 | 3 | 0 | 3 |
| COG7 | MRPL38 | 0.686463 | 4 | 0 | 3 |
| COG7 | ALDOA | 0.685928 | 4 | 0 | 3 |
| COG7 | RAB4B | 0.672478 | 3 | 0 | 3 |
| COG7 | PSMD4 | 0.672014 | 3 | 0 | 3 |
| COG7 | CNOT1 | 0.671636 | 4 | 0 | 3 |
| COG7 | FAM111B | 0.667217 | 4 | 0 | 3 |
| COG7 | ARHGEF5 | 0.66683 | 3 | 0 | 3 |
| COG7 | AQR | 0.659684 | 4 | 0 | 3 |
| COG7 | TRAF7 | 0.654951 | 4 | 0 | 4 |
| COG7 | MREG | 0.652933 | 3 | 0 | 3 |
| COG7 | ALG10 | 0.647859 | 4 | 0 | 3 |
| COG7 | GATC | 0.646961 | 5 | 0 | 4 |
| COG7 | SCNN1A | 0.64624 | 3 | 0 | 3 |
| COG7 | TET2 | 0.646006 | 3 | 0 | 3 |
| COG7 | MRPL10 | 0.64401 | 5 | 0 | 4 |
| COG7 | DHX30 | 0.643317 | 3 | 0 | 3 |
| COG7 | INTS9 | 0.641623 | 4 | 0 | 4 |
| COG7 | ZNF514 | 0.639414 | 3 | 0 | 3 |
For details and further investigation, click here
