| Full name: angiopoietin like 7 | Alias Symbol: CDT6|AngX | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 10218 | HGNC ID: HGNC:24078 | Ensembl Gene: ENSG00000171819 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANGPTL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANGPTL7 | 10218 | 206423_at | -0.2882 | 0.8170 | |
| GSE20347 | ANGPTL7 | 10218 | 206423_at | -0.0947 | 0.1944 | |
| GSE23400 | ANGPTL7 | 10218 | 206423_at | -0.1657 | 0.0013 | |
| GSE26886 | ANGPTL7 | 10218 | 206423_at | 0.0577 | 0.5881 | |
| GSE29001 | ANGPTL7 | 10218 | 206423_at | -0.2572 | 0.0405 | |
| GSE38129 | ANGPTL7 | 10218 | 206423_at | -0.6880 | 0.0019 | |
| GSE45670 | ANGPTL7 | 10218 | 206423_at | -0.8607 | 0.0002 | |
| GSE53622 | ANGPTL7 | 10218 | 77698 | -1.2106 | 0.0000 | |
| GSE53624 | ANGPTL7 | 10218 | 77698 | -1.7986 | 0.0000 | |
| GSE63941 | ANGPTL7 | 10218 | 206423_at | -0.0332 | 0.8284 | |
| GSE77861 | ANGPTL7 | 10218 | 206423_at | -0.0651 | 0.5383 | |
| GSE97050 | ANGPTL7 | 10218 | A_23_P114862 | -0.3417 | 0.3936 | |
| SRP133303 | ANGPTL7 | 10218 | RNAseq | -0.3308 | 0.2419 | |
| SRP159526 | ANGPTL7 | 10218 | RNAseq | -2.1683 | 0.0008 | |
| SRP219564 | ANGPTL7 | 10218 | RNAseq | -0.6677 | 0.5927 | |
| TCGA | ANGPTL7 | 10218 | RNAseq | -1.8238 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ANGPTL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANGPTL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANGPTL7 | 10218 | 0 | 5 | 25 | |
| GSE20123 | ANGPTL7 | 10218 | 0 | 4 | 26 | |
| GSE43470 | ANGPTL7 | 10218 | 6 | 5 | 32 | |
| GSE46452 | ANGPTL7 | 10218 | 7 | 1 | 51 | |
| GSE47630 | ANGPTL7 | 10218 | 8 | 4 | 28 | |
| GSE54993 | ANGPTL7 | 10218 | 3 | 1 | 66 | |
| GSE54994 | ANGPTL7 | 10218 | 11 | 4 | 38 | |
| GSE60625 | ANGPTL7 | 10218 | 0 | 0 | 11 | |
| GSE74703 | ANGPTL7 | 10218 | 5 | 3 | 28 | |
| GSE74704 | ANGPTL7 | 10218 | 0 | 0 | 20 | |
| TCGA | ANGPTL7 | 10218 | 10 | 22 | 64 |
Total number of gains: 50; Total number of losses: 49; Total Number of normals: 389.
Somatic mutations of ANGPTL7:
Generating mutation plots.
Highly correlated genes for ANGPTL7:
Showing top 20/838 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANGPTL7 | SORCS1 | 0.789084 | 4 | 0 | 4 |
| ANGPTL7 | XKR4 | 0.780376 | 5 | 0 | 5 |
| ANGPTL7 | CLEC3B | 0.771852 | 3 | 0 | 3 |
| ANGPTL7 | CYP21A2 | 0.760693 | 3 | 0 | 3 |
| ANGPTL7 | PGR | 0.758628 | 6 | 0 | 6 |
| ANGPTL7 | HOXA4 | 0.753439 | 5 | 0 | 5 |
| ANGPTL7 | KLHL30 | 0.747361 | 3 | 0 | 3 |
| ANGPTL7 | RBPMS2 | 0.746886 | 5 | 0 | 5 |
| ANGPTL7 | FNDC5 | 0.744506 | 4 | 0 | 4 |
| ANGPTL7 | HABP4 | 0.743732 | 6 | 0 | 5 |
| ANGPTL7 | CTNNA3 | 0.743143 | 6 | 0 | 6 |
| ANGPTL7 | NKIRAS1 | 0.738326 | 3 | 0 | 3 |
| ANGPTL7 | SGCA | 0.732691 | 10 | 0 | 9 |
| ANGPTL7 | AMIGO1 | 0.730692 | 3 | 0 | 3 |
| ANGPTL7 | PYGM | 0.727745 | 9 | 0 | 8 |
| ANGPTL7 | PI16 | 0.724904 | 6 | 0 | 5 |
| ANGPTL7 | NEGR1 | 0.721094 | 5 | 0 | 5 |
| ANGPTL7 | ANGPTL1 | 0.718482 | 5 | 0 | 5 |
| ANGPTL7 | ANO5 | 0.718466 | 5 | 0 | 5 |
| ANGPTL7 | MYOC | 0.7161 | 9 | 0 | 8 |
For details and further investigation, click here
