| Full name: collagen type V alpha 3 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 50509 | HGNC ID: HGNC:14864 | Ensembl Gene: ENSG00000080573 | OMIM ID: 120216 |
| Drug and gene relationship at DGIdb | |||
Expression of COL5A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL5A3 | 50509 | 52255_s_at | 1.2171 | 0.0321 | |
| GSE20347 | COL5A3 | 50509 | 52255_s_at | 0.2971 | 0.1361 | |
| GSE23400 | COL5A3 | 50509 | 52255_s_at | 0.4071 | 0.0000 | |
| GSE26886 | COL5A3 | 50509 | 52255_s_at | 1.0526 | 0.0300 | |
| GSE29001 | COL5A3 | 50509 | 52255_s_at | 0.2583 | 0.4753 | |
| GSE38129 | COL5A3 | 50509 | 218975_at | 0.1300 | 0.4519 | |
| GSE45670 | COL5A3 | 50509 | 52255_s_at | 0.7068 | 0.0514 | |
| GSE53622 | COL5A3 | 50509 | 83054 | 1.4505 | 0.0000 | |
| GSE53624 | COL5A3 | 50509 | 83054 | 1.3667 | 0.0000 | |
| GSE63941 | COL5A3 | 50509 | 52255_s_at | -0.3430 | 0.2908 | |
| GSE77861 | COL5A3 | 50509 | 52255_s_at | -0.0309 | 0.9400 | |
| GSE97050 | COL5A3 | 50509 | A_23_P55749 | 0.6754 | 0.1450 | |
| SRP007169 | COL5A3 | 50509 | RNAseq | 2.5575 | 0.0000 | |
| SRP008496 | COL5A3 | 50509 | RNAseq | 2.4842 | 0.0000 | |
| SRP064894 | COL5A3 | 50509 | RNAseq | 1.6857 | 0.0000 | |
| SRP133303 | COL5A3 | 50509 | RNAseq | 1.9400 | 0.0000 | |
| SRP159526 | COL5A3 | 50509 | RNAseq | 0.1936 | 0.5201 | |
| SRP193095 | COL5A3 | 50509 | RNAseq | 2.3372 | 0.0000 | |
| SRP219564 | COL5A3 | 50509 | RNAseq | 0.9613 | 0.1281 | |
| TCGA | COL5A3 | 50509 | RNAseq | 0.7049 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by COL5A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL5A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL5A3 | 50509 | 4 | 2 | 24 | |
| GSE20123 | COL5A3 | 50509 | 3 | 1 | 26 | |
| GSE43470 | COL5A3 | 50509 | 3 | 6 | 34 | |
| GSE46452 | COL5A3 | 50509 | 47 | 1 | 11 | |
| GSE47630 | COL5A3 | 50509 | 5 | 7 | 28 | |
| GSE54993 | COL5A3 | 50509 | 16 | 3 | 51 | |
| GSE54994 | COL5A3 | 50509 | 7 | 13 | 33 | |
| GSE60625 | COL5A3 | 50509 | 9 | 0 | 2 | |
| GSE74703 | COL5A3 | 50509 | 3 | 4 | 29 | |
| GSE74704 | COL5A3 | 50509 | 0 | 1 | 19 | |
| TCGA | COL5A3 | 50509 | 12 | 17 | 67 |
Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.
Somatic mutations of COL5A3:
Generating mutation plots.
Highly correlated genes for COL5A3:
Showing top 20/1043 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL5A3 | ZNF469 | 0.746975 | 8 | 0 | 8 |
| COL5A3 | GEMIN5 | 0.73368 | 3 | 0 | 3 |
| COL5A3 | RUNX1-IT1 | 0.724476 | 6 | 0 | 6 |
| COL5A3 | LRRC8C | 0.718621 | 3 | 0 | 3 |
| COL5A3 | FAM89A | 0.713217 | 3 | 0 | 3 |
| COL5A3 | ARSI | 0.71272 | 7 | 0 | 7 |
| COL5A3 | C10orf55 | 0.707828 | 4 | 0 | 4 |
| COL5A3 | LOXL2 | 0.707424 | 11 | 0 | 10 |
| COL5A3 | COMP | 0.707066 | 3 | 0 | 3 |
| COL5A3 | TOP1MT | 0.70538 | 5 | 0 | 5 |
| COL5A3 | MRPS17 | 0.705062 | 3 | 0 | 3 |
| COL5A3 | CRLF1 | 0.681018 | 3 | 0 | 3 |
| COL5A3 | SPOCD1 | 0.680895 | 7 | 0 | 7 |
| COL5A3 | FHOD1 | 0.678809 | 12 | 0 | 10 |
| COL5A3 | OLFM2 | 0.676664 | 4 | 0 | 4 |
| COL5A3 | ADAMTS14 | 0.674425 | 4 | 0 | 3 |
| COL5A3 | WDYHV1 | 0.673803 | 5 | 0 | 5 |
| COL5A3 | TRADD | 0.673214 | 3 | 0 | 3 |
| COL5A3 | SERPINE1 | 0.673088 | 13 | 0 | 11 |
| COL5A3 | TAF2 | 0.672966 | 5 | 0 | 5 |
For details and further investigation, click here
