| Full name: TAO kinase 3 | Alias Symbol: JIK|DPK|MAP3K18 | ||
| Type: protein-coding gene | Cytoband: 12q | ||
| Entrez ID: 51347 | HGNC ID: HGNC:18133 | Ensembl Gene: ENSG00000135090 | OMIM ID: 616711 |
| Drug and gene relationship at DGIdb | |||
Expression of TAOK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAOK3 | 51347 | 220761_s_at | -0.2686 | 0.4897 | |
| GSE20347 | TAOK3 | 51347 | 220761_s_at | -0.9162 | 0.0000 | |
| GSE23400 | TAOK3 | 51347 | 220761_s_at | -0.4094 | 0.0000 | |
| GSE26886 | TAOK3 | 51347 | 220761_s_at | 0.1998 | 0.5283 | |
| GSE29001 | TAOK3 | 51347 | 220761_s_at | -0.9566 | 0.0557 | |
| GSE38129 | TAOK3 | 51347 | 220761_s_at | -0.9135 | 0.0000 | |
| GSE45670 | TAOK3 | 51347 | 220761_s_at | -0.3813 | 0.0118 | |
| GSE53622 | TAOK3 | 51347 | 54593 | -0.6586 | 0.0000 | |
| GSE53624 | TAOK3 | 51347 | 54593 | -0.8784 | 0.0000 | |
| GSE63941 | TAOK3 | 51347 | 220761_s_at | -1.0669 | 0.0665 | |
| GSE77861 | TAOK3 | 51347 | 220761_s_at | -0.3859 | 0.1146 | |
| GSE97050 | TAOK3 | 51347 | A_23_P2203 | -0.5016 | 0.1195 | |
| SRP007169 | TAOK3 | 51347 | RNAseq | -0.9609 | 0.0250 | |
| SRP008496 | TAOK3 | 51347 | RNAseq | -0.7202 | 0.0065 | |
| SRP064894 | TAOK3 | 51347 | RNAseq | -0.5418 | 0.0002 | |
| SRP133303 | TAOK3 | 51347 | RNAseq | -0.3310 | 0.0509 | |
| SRP159526 | TAOK3 | 51347 | RNAseq | -1.0085 | 0.0000 | |
| SRP193095 | TAOK3 | 51347 | RNAseq | -0.7493 | 0.0000 | |
| SRP219564 | TAOK3 | 51347 | RNAseq | -0.6358 | 0.0256 | |
| TCGA | TAOK3 | 51347 | RNAseq | -0.1636 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TAOK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAOK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAOK3 | 51347 | 6 | 2 | 22 | |
| GSE20123 | TAOK3 | 51347 | 6 | 2 | 22 | |
| GSE43470 | TAOK3 | 51347 | 2 | 1 | 40 | |
| GSE46452 | TAOK3 | 51347 | 9 | 1 | 49 | |
| GSE47630 | TAOK3 | 51347 | 9 | 3 | 28 | |
| GSE54993 | TAOK3 | 51347 | 0 | 5 | 65 | |
| GSE54994 | TAOK3 | 51347 | 6 | 6 | 41 | |
| GSE60625 | TAOK3 | 51347 | 0 | 0 | 11 | |
| GSE74703 | TAOK3 | 51347 | 2 | 0 | 34 | |
| GSE74704 | TAOK3 | 51347 | 3 | 2 | 15 | |
| TCGA | TAOK3 | 51347 | 21 | 11 | 64 |
Total number of gains: 64; Total number of losses: 33; Total Number of normals: 391.
Somatic mutations of TAOK3:
Generating mutation plots.
Highly correlated genes for TAOK3:
Showing top 20/1204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAOK3 | ASH1L | 0.772883 | 3 | 0 | 3 |
| TAOK3 | ZNF394 | 0.763766 | 4 | 0 | 4 |
| TAOK3 | GPR108 | 0.756578 | 3 | 0 | 3 |
| TAOK3 | ZNF416 | 0.755715 | 3 | 0 | 3 |
| TAOK3 | VPS29 | 0.753904 | 3 | 0 | 3 |
| TAOK3 | CLK1 | 0.735586 | 3 | 0 | 3 |
| TAOK3 | COG6 | 0.723244 | 4 | 0 | 3 |
| TAOK3 | CTTNBP2NL | 0.720097 | 5 | 0 | 5 |
| TAOK3 | COPG2 | 0.717028 | 3 | 0 | 3 |
| TAOK3 | CTSO | 0.71618 | 3 | 0 | 3 |
| TAOK3 | PPP2R5E | 0.715893 | 4 | 0 | 3 |
| TAOK3 | EIF4E3 | 0.71527 | 5 | 0 | 5 |
| TAOK3 | RAB18 | 0.698778 | 3 | 0 | 3 |
| TAOK3 | SCRN3 | 0.697515 | 3 | 0 | 3 |
| TAOK3 | KAT2B | 0.694066 | 9 | 0 | 9 |
| TAOK3 | CDC42SE1 | 0.692906 | 3 | 0 | 3 |
| TAOK3 | TMEM220 | 0.691791 | 4 | 0 | 4 |
| TAOK3 | ALKBH3 | 0.68993 | 3 | 0 | 3 |
| TAOK3 | CLEC3B | 0.688191 | 3 | 0 | 3 |
| TAOK3 | LRRFIP2 | 0.685365 | 10 | 0 | 9 |
For details and further investigation, click here
