| Full name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | Alias Symbol: ADH-4 | ||
| Type: protein-coding gene | Cytoband: 4q23 | ||
| Entrez ID: 131 | HGNC ID: HGNC:256 | Ensembl Gene: ENSG00000196344 | OMIM ID: 600086 |
| Drug and gene relationship at DGIdb | |||
Expression of ADH7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADH7 | 131 | 210505_at | -2.1260 | 0.2922 | |
| GSE20347 | ADH7 | 131 | 210505_at | -2.1773 | 0.0001 | |
| GSE23400 | ADH7 | 131 | 210505_at | -1.2916 | 0.0000 | |
| GSE26886 | ADH7 | 131 | 210505_at | -4.2965 | 0.0000 | |
| GSE29001 | ADH7 | 131 | 210505_at | -1.7599 | 0.0010 | |
| GSE38129 | ADH7 | 131 | 210505_at | -1.1352 | 0.0919 | |
| GSE45670 | ADH7 | 131 | 210505_at | -1.8614 | 0.0120 | |
| GSE53622 | ADH7 | 131 | 2225 | -2.8353 | 0.0000 | |
| GSE53624 | ADH7 | 131 | 2225 | -3.1862 | 0.0000 | |
| GSE63941 | ADH7 | 131 | 210505_at | 2.0105 | 0.3585 | |
| GSE77861 | ADH7 | 131 | 210505_at | -1.8064 | 0.0641 | |
| GSE97050 | ADH7 | 131 | A_23_P92562 | -1.6964 | 0.1338 | |
| SRP007169 | ADH7 | 131 | RNAseq | -2.0461 | 0.0069 | |
| SRP008496 | ADH7 | 131 | RNAseq | -1.7152 | 0.0464 | |
| SRP064894 | ADH7 | 131 | RNAseq | -2.7398 | 0.0001 | |
| SRP133303 | ADH7 | 131 | RNAseq | -2.8713 | 0.0000 | |
| SRP159526 | ADH7 | 131 | RNAseq | -1.3051 | 0.2113 | |
| SRP193095 | ADH7 | 131 | RNAseq | -2.2551 | 0.0000 | |
| SRP219564 | ADH7 | 131 | RNAseq | -1.9261 | 0.1753 | |
| TCGA | ADH7 | 131 | RNAseq | 0.1612 | 0.7374 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by ADH7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADH7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADH7 | 131 | 0 | 12 | 18 | |
| GSE20123 | ADH7 | 131 | 0 | 12 | 18 | |
| GSE43470 | ADH7 | 131 | 0 | 13 | 30 | |
| GSE46452 | ADH7 | 131 | 1 | 36 | 22 | |
| GSE47630 | ADH7 | 131 | 0 | 20 | 20 | |
| GSE54993 | ADH7 | 131 | 9 | 0 | 61 | |
| GSE54994 | ADH7 | 131 | 1 | 11 | 41 | |
| GSE60625 | ADH7 | 131 | 0 | 3 | 8 | |
| GSE74703 | ADH7 | 131 | 0 | 11 | 25 | |
| GSE74704 | ADH7 | 131 | 0 | 6 | 14 | |
| TCGA | ADH7 | 131 | 8 | 41 | 47 |
Total number of gains: 19; Total number of losses: 165; Total Number of normals: 304.
Somatic mutations of ADH7:
Generating mutation plots.
Highly correlated genes for ADH7:
Showing top 20/1141 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADH7 | ALDH3A1 | 0.785767 | 13 | 0 | 13 |
| ADH7 | SCEL | 0.767746 | 11 | 0 | 11 |
| ADH7 | PGD | 0.765316 | 13 | 0 | 12 |
| ADH7 | CYP2C18 | 0.759951 | 11 | 0 | 10 |
| ADH7 | PPL | 0.752594 | 12 | 0 | 11 |
| ADH7 | CERS3 | 0.751941 | 5 | 0 | 5 |
| ADH7 | ZNF750 | 0.748241 | 10 | 0 | 10 |
| ADH7 | TMPRSS11E | 0.746359 | 11 | 0 | 11 |
| ADH7 | CSTB | 0.7444 | 11 | 0 | 11 |
| ADH7 | FAM3B | 0.744016 | 6 | 0 | 6 |
| ADH7 | CYP4F3 | 0.741475 | 12 | 0 | 12 |
| ADH7 | ACPP | 0.738708 | 12 | 0 | 11 |
| ADH7 | LIPH | 0.737676 | 6 | 0 | 6 |
| ADH7 | MALL | 0.736607 | 11 | 0 | 11 |
| ADH7 | EMP1 | 0.735298 | 11 | 0 | 11 |
| ADH7 | KRT4 | 0.734702 | 11 | 0 | 10 |
| ADH7 | OTOP3 | 0.733639 | 3 | 0 | 3 |
| ADH7 | EVPL | 0.731501 | 11 | 0 | 11 |
| ADH7 | KRT13 | 0.731459 | 12 | 0 | 11 |
| ADH7 | CYSRT1 | 0.729312 | 6 | 0 | 6 |
For details and further investigation, click here
