| Full name: mediator complex subunit 28 | Alias Symbol: EG1|DKFZP434N185|magicin | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 80306 | HGNC ID: HGNC:24628 | Ensembl Gene: ENSG00000118579 | OMIM ID: 610311 |
| Drug and gene relationship at DGIdb | |||
Expression of MED28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED28 | 80306 | 228992_at | 0.2178 | 0.5452 | |
| GSE20347 | MED28 | 80306 | 218438_s_at | -0.0609 | 0.8106 | |
| GSE23400 | MED28 | 80306 | 218438_s_at | 0.3304 | 0.0000 | |
| GSE26886 | MED28 | 80306 | 228992_at | -0.5796 | 0.0056 | |
| GSE29001 | MED28 | 80306 | 218438_s_at | 0.2338 | 0.4455 | |
| GSE38129 | MED28 | 80306 | 218438_s_at | 0.1937 | 0.3041 | |
| GSE45670 | MED28 | 80306 | 228992_at | -0.1971 | 0.1904 | |
| GSE53622 | MED28 | 80306 | 140863 | -0.6215 | 0.0000 | |
| GSE53624 | MED28 | 80306 | 140863 | -0.4024 | 0.0000 | |
| GSE63941 | MED28 | 80306 | 228992_at | 0.4917 | 0.2662 | |
| GSE77861 | MED28 | 80306 | 228992_at | -0.5396 | 0.0213 | |
| GSE97050 | MED28 | 80306 | A_24_P538478 | -0.2146 | 0.3051 | |
| SRP007169 | MED28 | 80306 | RNAseq | -0.6862 | 0.0798 | |
| SRP008496 | MED28 | 80306 | RNAseq | -0.5669 | 0.0092 | |
| SRP064894 | MED28 | 80306 | RNAseq | -0.2142 | 0.1079 | |
| SRP133303 | MED28 | 80306 | RNAseq | -0.3646 | 0.0005 | |
| SRP159526 | MED28 | 80306 | RNAseq | -0.3592 | 0.0647 | |
| SRP193095 | MED28 | 80306 | RNAseq | -0.3930 | 0.0000 | |
| SRP219564 | MED28 | 80306 | RNAseq | -0.1755 | 0.5148 | |
| TCGA | MED28 | 80306 | RNAseq | -0.0387 | 0.5047 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED28 | 80306 | 0 | 18 | 12 | |
| GSE20123 | MED28 | 80306 | 0 | 18 | 12 | |
| GSE43470 | MED28 | 80306 | 1 | 15 | 27 | |
| GSE46452 | MED28 | 80306 | 1 | 36 | 22 | |
| GSE47630 | MED28 | 80306 | 1 | 19 | 20 | |
| GSE54993 | MED28 | 80306 | 9 | 0 | 61 | |
| GSE54994 | MED28 | 80306 | 4 | 12 | 37 | |
| GSE60625 | MED28 | 80306 | 0 | 0 | 11 | |
| GSE74703 | MED28 | 80306 | 1 | 13 | 22 | |
| GSE74704 | MED28 | 80306 | 0 | 11 | 9 | |
| TCGA | MED28 | 80306 | 9 | 48 | 39 |
Total number of gains: 26; Total number of losses: 190; Total Number of normals: 272.
Somatic mutations of MED28:
Generating mutation plots.
Highly correlated genes for MED28:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED28 | ACVR2A | 0.711453 | 3 | 0 | 3 |
| MED28 | SLC44A3 | 0.710682 | 4 | 0 | 3 |
| MED28 | ZNF140 | 0.705722 | 3 | 0 | 3 |
| MED28 | COG6 | 0.696312 | 3 | 0 | 3 |
| MED28 | CPEB2 | 0.695181 | 3 | 0 | 3 |
| MED28 | ZNF615 | 0.68048 | 4 | 0 | 4 |
| MED28 | TBC1D22B | 0.679407 | 3 | 0 | 3 |
| MED28 | NFKB1 | 0.679204 | 3 | 0 | 3 |
| MED28 | SPCS2 | 0.673753 | 4 | 0 | 4 |
| MED28 | TMEM61 | 0.672234 | 4 | 0 | 3 |
| MED28 | IMPACT | 0.672073 | 3 | 0 | 3 |
| MED28 | NCKAP1 | 0.668438 | 4 | 0 | 3 |
| MED28 | GRAMD1C | 0.663692 | 4 | 0 | 4 |
| MED28 | ADHFE1 | 0.662891 | 3 | 0 | 3 |
| MED28 | SNRNP200 | 0.66266 | 3 | 0 | 3 |
| MED28 | IMPA1 | 0.662064 | 3 | 0 | 3 |
| MED28 | GLUD1 | 0.661411 | 3 | 0 | 3 |
| MED28 | POLR3C | 0.660798 | 5 | 0 | 4 |
| MED28 | ANXA3 | 0.658573 | 3 | 0 | 3 |
| MED28 | ZNF470 | 0.655197 | 3 | 0 | 3 |
For details and further investigation, click here
