| Full name: carboxypeptidase M | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q15 | ||
| Entrez ID: 1368 | HGNC ID: HGNC:2311 | Ensembl Gene: ENSG00000135678 | OMIM ID: 114860 |
| Drug and gene relationship at DGIdb | |||
Expression of CPM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPM | 1368 | 235706_at | -0.3233 | 0.5181 | |
| GSE20347 | CPM | 1368 | 217557_s_at | -0.1456 | 0.0098 | |
| GSE23400 | CPM | 1368 | 217557_s_at | -0.1396 | 0.0000 | |
| GSE26886 | CPM | 1368 | 235706_at | -1.4923 | 0.0000 | |
| GSE29001 | CPM | 1368 | 206100_at | -0.7536 | 0.1089 | |
| GSE38129 | CPM | 1368 | 217557_s_at | -0.1178 | 0.0466 | |
| GSE45670 | CPM | 1368 | 206100_at | 0.4036 | 0.3216 | |
| GSE63941 | CPM | 1368 | 235706_at | -0.3615 | 0.5594 | |
| GSE77861 | CPM | 1368 | 217557_s_at | -0.0700 | 0.5275 | |
| SRP007169 | CPM | 1368 | RNAseq | 0.8435 | 0.3812 | |
| SRP008496 | CPM | 1368 | RNAseq | -1.2052 | 0.0033 | |
| SRP064894 | CPM | 1368 | RNAseq | 1.2816 | 0.0022 | |
| SRP133303 | CPM | 1368 | RNAseq | 0.4326 | 0.1002 | |
| SRP159526 | CPM | 1368 | RNAseq | 0.3014 | 0.5271 | |
| SRP193095 | CPM | 1368 | RNAseq | -0.0135 | 0.9381 | |
| SRP219564 | CPM | 1368 | RNAseq | 0.9407 | 0.0251 | |
| TCGA | CPM | 1368 | RNAseq | -0.6048 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by CPM expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CPM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPM | 1368 | 6 | 1 | 23 | |
| GSE20123 | CPM | 1368 | 6 | 0 | 24 | |
| GSE43470 | CPM | 1368 | 5 | 0 | 38 | |
| GSE46452 | CPM | 1368 | 12 | 0 | 47 | |
| GSE47630 | CPM | 1368 | 10 | 1 | 29 | |
| GSE54993 | CPM | 1368 | 0 | 7 | 63 | |
| GSE54994 | CPM | 1368 | 7 | 1 | 45 | |
| GSE60625 | CPM | 1368 | 0 | 0 | 11 | |
| GSE74703 | CPM | 1368 | 5 | 0 | 31 | |
| GSE74704 | CPM | 1368 | 5 | 0 | 15 | |
| TCGA | CPM | 1368 | 23 | 8 | 65 |
Total number of gains: 79; Total number of losses: 18; Total Number of normals: 391.
Somatic mutations of CPM:
Generating mutation plots.
Highly correlated genes for CPM:
Showing top 20/263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPM | MPEG1 | 0.689932 | 3 | 0 | 3 |
| CPM | ANKRD44 | 0.688471 | 4 | 0 | 3 |
| CPM | CA4 | 0.667324 | 4 | 0 | 4 |
| CPM | PDE7B | 0.663157 | 3 | 0 | 3 |
| CPM | LRG1 | 0.652965 | 4 | 0 | 4 |
| CPM | GSG1 | 0.63479 | 5 | 0 | 4 |
| CPM | P2RX3 | 0.630746 | 5 | 0 | 4 |
| CPM | PCYOX1 | 0.629388 | 3 | 0 | 3 |
| CPM | KCTD10 | 0.629124 | 3 | 0 | 3 |
| CPM | RHBDL2 | 0.624286 | 4 | 0 | 3 |
| CPM | IRAK2 | 0.621486 | 3 | 0 | 3 |
| CPM | APOA2 | 0.615694 | 5 | 0 | 4 |
| CPM | KLRB1 | 0.612704 | 4 | 0 | 3 |
| CPM | KCNG2 | 0.611347 | 6 | 0 | 6 |
| CPM | RNF183 | 0.610002 | 4 | 0 | 3 |
| CPM | C1orf210 | 0.609244 | 3 | 0 | 3 |
| CPM | YIPF1 | 0.608446 | 4 | 0 | 3 |
| CPM | PEX3 | 0.607677 | 3 | 0 | 3 |
| CPM | UBE2D3 | 0.606181 | 3 | 0 | 3 |
| CPM | HS3ST1 | 0.602205 | 5 | 0 | 3 |
For details and further investigation, click here
