| Full name: cysteine rich secretory protein LCCL domain containing 1 | Alias Symbol: Cocoacrisp|DKFZp762F133 | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 83690 | HGNC ID: HGNC:18206 | Ensembl Gene: ENSG00000121005 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CRISPLD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRISPLD1 | 83690 | 223475_at | 0.7430 | 0.1943 | |
| GSE26886 | CRISPLD1 | 83690 | 223475_at | 1.4880 | 0.0208 | |
| GSE45670 | CRISPLD1 | 83690 | 223475_at | -0.2685 | 0.5196 | |
| GSE53622 | CRISPLD1 | 83690 | 99682 | 0.0955 | 0.7089 | |
| GSE53624 | CRISPLD1 | 83690 | 99682 | 0.3429 | 0.0808 | |
| GSE63941 | CRISPLD1 | 83690 | 223475_at | -2.1787 | 0.0443 | |
| GSE77861 | CRISPLD1 | 83690 | 223475_at | 0.5362 | 0.1056 | |
| SRP007169 | CRISPLD1 | 83690 | RNAseq | 1.3461 | 0.0912 | |
| SRP008496 | CRISPLD1 | 83690 | RNAseq | 1.7757 | 0.0006 | |
| SRP064894 | CRISPLD1 | 83690 | RNAseq | 1.2576 | 0.0001 | |
| SRP133303 | CRISPLD1 | 83690 | RNAseq | 0.4913 | 0.0665 | |
| SRP159526 | CRISPLD1 | 83690 | RNAseq | 1.2012 | 0.0191 | |
| SRP219564 | CRISPLD1 | 83690 | RNAseq | 0.7813 | 0.0892 | |
| TCGA | CRISPLD1 | 83690 | RNAseq | 0.6889 | 0.0001 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by CRISPLD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRISPLD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRISPLD1 | 83690 | 15 | 1 | 14 | |
| GSE20123 | CRISPLD1 | 83690 | 16 | 1 | 13 | |
| GSE43470 | CRISPLD1 | 83690 | 19 | 1 | 23 | |
| GSE46452 | CRISPLD1 | 83690 | 22 | 0 | 37 | |
| GSE47630 | CRISPLD1 | 83690 | 23 | 0 | 17 | |
| GSE54993 | CRISPLD1 | 83690 | 0 | 19 | 51 | |
| GSE54994 | CRISPLD1 | 83690 | 30 | 0 | 23 | |
| GSE60625 | CRISPLD1 | 83690 | 0 | 4 | 7 | |
| GSE74703 | CRISPLD1 | 83690 | 16 | 1 | 19 | |
| GSE74704 | CRISPLD1 | 83690 | 11 | 0 | 9 | |
| TCGA | CRISPLD1 | 83690 | 51 | 2 | 43 |
Total number of gains: 203; Total number of losses: 29; Total Number of normals: 256.
Somatic mutations of CRISPLD1:
Generating mutation plots.
Highly correlated genes for CRISPLD1:
Showing top 20/90 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRISPLD1 | HLTF | 0.710869 | 3 | 0 | 3 |
| CRISPLD1 | ASXL1 | 0.685491 | 3 | 0 | 3 |
| CRISPLD1 | MAK16 | 0.671597 | 3 | 0 | 3 |
| CRISPLD1 | HOXC9 | 0.661457 | 3 | 0 | 3 |
| CRISPLD1 | NAPEPLD | 0.66015 | 3 | 0 | 3 |
| CRISPLD1 | TBL1XR1 | 0.651245 | 3 | 0 | 3 |
| CRISPLD1 | MFHAS1 | 0.649199 | 3 | 0 | 3 |
| CRISPLD1 | DDHD1 | 0.648561 | 4 | 0 | 4 |
| CRISPLD1 | GPNMB | 0.645672 | 3 | 0 | 3 |
| CRISPLD1 | MTRR | 0.641337 | 3 | 0 | 3 |
| CRISPLD1 | KIAA0895 | 0.639791 | 3 | 0 | 3 |
| CRISPLD1 | MEST | 0.63688 | 3 | 0 | 3 |
| CRISPLD1 | U2SURP | 0.63164 | 3 | 0 | 3 |
| CRISPLD1 | ZNF639 | 0.626414 | 3 | 0 | 3 |
| CRISPLD1 | GPR158 | 0.624898 | 3 | 0 | 3 |
| CRISPLD1 | MAGEA11 | 0.624716 | 3 | 0 | 3 |
| CRISPLD1 | CUX1 | 0.622536 | 3 | 0 | 3 |
| CRISPLD1 | LOXL1-AS1 | 0.622354 | 3 | 0 | 3 |
| CRISPLD1 | FARP1 | 0.621415 | 4 | 0 | 3 |
| CRISPLD1 | SMYD4 | 0.620435 | 3 | 0 | 3 |
For details and further investigation, click here
