| Full name: SMC5 antisense RNA 1 (head to head) | Alias Symbol: MAMDC2-AS2 | ||
| Type: non-coding RNA | Cytoband: 9q21.12 | ||
| Entrez ID: 100507299 | HGNC ID: HGNC:48718 | Ensembl Gene: ENSG00000268364 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMC5-AS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMC5-AS1 | 100507299 | 1557693_at | -0.3993 | 0.1779 | |
| GSE26886 | SMC5-AS1 | 100507299 | 1557693_at | -0.0448 | 0.7153 | |
| GSE45670 | SMC5-AS1 | 100507299 | 1557693_at | -0.3198 | 0.0005 | |
| GSE63941 | SMC5-AS1 | 100507299 | 1557693_at | 0.1847 | 0.2785 | |
| GSE77861 | SMC5-AS1 | 100507299 | 1557693_at | -0.3472 | 0.0072 | |
| SRP133303 | SMC5-AS1 | 100507299 | RNAseq | -0.3487 | 0.0860 | |
| SRP159526 | SMC5-AS1 | 100507299 | RNAseq | -0.6418 | 0.2332 | |
| SRP193095 | SMC5-AS1 | 100507299 | RNAseq | -0.3248 | 0.0087 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of SMC5-AS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMC5-AS1 | 100507299 | 6 | 10 | 14 | |
| GSE20123 | SMC5-AS1 | 100507299 | 6 | 10 | 14 | |
| GSE43470 | SMC5-AS1 | 100507299 | 6 | 5 | 32 | |
| GSE46452 | SMC5-AS1 | 100507299 | 6 | 14 | 39 | |
| GSE47630 | SMC5-AS1 | 100507299 | 1 | 19 | 20 | |
| GSE54993 | SMC5-AS1 | 100507299 | 5 | 1 | 64 | |
| GSE54994 | SMC5-AS1 | 100507299 | 4 | 13 | 36 | |
| GSE60625 | SMC5-AS1 | 100507299 | 0 | 0 | 11 | |
| GSE74703 | SMC5-AS1 | 100507299 | 5 | 4 | 27 | |
| GSE74704 | SMC5-AS1 | 100507299 | 3 | 7 | 10 |
Total number of gains: 42; Total number of losses: 83; Total Number of normals: 267.
Somatic mutations of SMC5-AS1:
Generating mutation plots.
Highly correlated genes for SMC5-AS1:
Showing top 20/338 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMC5-AS1 | PDLIM5 | 0.815612 | 3 | 0 | 3 |
| SMC5-AS1 | ABLIM1 | 0.801356 | 3 | 0 | 3 |
| SMC5-AS1 | CCNG2 | 0.773231 | 3 | 0 | 3 |
| SMC5-AS1 | EMP1 | 0.766204 | 3 | 0 | 3 |
| SMC5-AS1 | IL12A | 0.760709 | 3 | 0 | 3 |
| SMC5-AS1 | IL12A-AS1 | 0.759747 | 3 | 0 | 3 |
| SMC5-AS1 | UBL3 | 0.757902 | 3 | 0 | 3 |
| SMC5-AS1 | CRYBG3 | 0.757034 | 3 | 0 | 3 |
| SMC5-AS1 | FAM3D | 0.75442 | 3 | 0 | 3 |
| SMC5-AS1 | HPGD | 0.753152 | 3 | 0 | 3 |
| SMC5-AS1 | FAM214A | 0.752331 | 3 | 0 | 3 |
| SMC5-AS1 | GBP6 | 0.750832 | 3 | 0 | 3 |
| SMC5-AS1 | BLNK | 0.745405 | 3 | 0 | 3 |
| SMC5-AS1 | LMO7 | 0.742168 | 3 | 0 | 3 |
| SMC5-AS1 | C4orf3 | 0.74132 | 3 | 0 | 3 |
| SMC5-AS1 | CHRM1 | 0.741077 | 3 | 0 | 3 |
| SMC5-AS1 | C18orf25 | 0.740635 | 3 | 0 | 3 |
| SMC5-AS1 | A2ML1 | 0.739559 | 3 | 0 | 3 |
| SMC5-AS1 | KAT2B | 0.739504 | 3 | 0 | 3 |
| SMC5-AS1 | SNX9 | 0.73843 | 3 | 0 | 3 |
For details and further investigation, click here