| Full name: actin beta like 2 | Alias Symbol: DKFZp686D0972 | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 345651 | HGNC ID: HGNC:17780 | Ensembl Gene: ENSG00000169067 | OMIM ID: 614835 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTBL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ACTBL2 | 345651 | 127366 | -1.4253 | 0.0000 | |
| GSE53624 | ACTBL2 | 345651 | 127366 | -0.9952 | 0.0000 | |
| GSE97050 | ACTBL2 | 345651 | A_24_P6903 | -1.0709 | 0.1512 | |
| TCGA | ACTBL2 | 345651 | RNAseq | 1.7920 | 0.0213 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ACTBL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTBL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTBL2 | 345651 | 0 | 13 | 17 | |
| GSE20123 | ACTBL2 | 345651 | 0 | 13 | 17 | |
| GSE43470 | ACTBL2 | 345651 | 1 | 12 | 30 | |
| GSE46452 | ACTBL2 | 345651 | 0 | 28 | 31 | |
| GSE47630 | ACTBL2 | 345651 | 2 | 16 | 22 | |
| GSE54993 | ACTBL2 | 345651 | 8 | 1 | 61 | |
| GSE54994 | ACTBL2 | 345651 | 2 | 19 | 32 | |
| GSE60625 | ACTBL2 | 345651 | 0 | 0 | 11 | |
| GSE74703 | ACTBL2 | 345651 | 1 | 9 | 26 | |
| GSE74704 | ACTBL2 | 345651 | 0 | 6 | 14 | |
| TCGA | ACTBL2 | 345651 | 7 | 46 | 43 |
Total number of gains: 21; Total number of losses: 163; Total Number of normals: 304.
Somatic mutations of ACTBL2:
Generating mutation plots.
Highly correlated genes for ACTBL2:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTBL2 | ACTA2 | 0.896103 | 3 | 0 | 3 |
| ACTBL2 | ACTG2 | 0.879879 | 3 | 0 | 3 |
| ACTBL2 | MYL5 | 0.859608 | 3 | 0 | 3 |
| ACTBL2 | TAGLN | 0.852587 | 3 | 0 | 3 |
| ACTBL2 | MYLK | 0.85049 | 3 | 0 | 3 |
| ACTBL2 | CSRP1 | 0.848645 | 3 | 0 | 3 |
| ACTBL2 | MYL9 | 0.845606 | 3 | 0 | 3 |
| ACTBL2 | LMOD1 | 0.832894 | 3 | 0 | 3 |
| ACTBL2 | TPM2 | 0.832134 | 3 | 0 | 3 |
| ACTBL2 | PPP1R12B | 0.828357 | 3 | 0 | 3 |
| ACTBL2 | HMHB1 | 0.82619 | 3 | 0 | 3 |
| ACTBL2 | SYNM | 0.81883 | 3 | 0 | 3 |
| ACTBL2 | TPM1 | 0.817981 | 3 | 0 | 3 |
| ACTBL2 | LPP | 0.816459 | 3 | 0 | 3 |
| ACTBL2 | SORBS1 | 0.808719 | 3 | 0 | 3 |
| ACTBL2 | NEXN | 0.807452 | 3 | 0 | 3 |
| ACTBL2 | SMTN | 0.807159 | 3 | 0 | 3 |
| ACTBL2 | PGM5 | 0.806636 | 3 | 0 | 3 |
| ACTBL2 | DES | 0.803398 | 3 | 0 | 3 |
| ACTBL2 | ATP1A2 | 0.801447 | 3 | 0 | 3 |
For details and further investigation, click here
