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Multi-Omics Database of ESCC

 

CYB5B

 

Full name: cytochrome b5 type B Alias Symbol: CYB5-M
Type: protein-coding gene Cytoband: 16q22.1
Entrez ID: 80777 HGNC ID: HGNC:24374 Ensembl Gene: ENSG00000103018 OMIM ID: 611964
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CYB5B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CYB5B 80777 201634_s_at 0.2485 0.7899
GSE20347 CYB5B 80777 201634_s_at 0.2420 0.1821
GSE23400 CYB5B 80777 201633_s_at 0.1443 0.0009
GSE26886 CYB5B 80777 201634_s_at -0.1121 0.6836
GSE29001 CYB5B 80777 201634_s_at 0.2300 0.5807
GSE38129 CYB5B 80777 201634_s_at 0.4041 0.0026
GSE45670 CYB5B 80777 201634_s_at 0.3111 0.0555
GSE63941 CYB5B 80777 201633_s_at 0.9645 0.0304
GSE77861 CYB5B 80777 201633_s_at 0.1568 0.5253
GSE97050 CYB5B 80777 A_33_P3357535 -0.4244 0.2227
SRP007169 CYB5B 80777 RNAseq 0.4287 0.2724
SRP008496 CYB5B 80777 RNAseq 0.2866 0.3069
SRP064894 CYB5B 80777 RNAseq 0.0080 0.9482
SRP133303 CYB5B 80777 RNAseq 0.4354 0.0001
SRP159526 CYB5B 80777 RNAseq 0.4404 0.0104
SRP193095 CYB5B 80777 RNAseq 0.4282 0.0312
SRP219564 CYB5B 80777 RNAseq -0.0238 0.9551
TCGA CYB5B 80777 RNAseq 0.1323 0.0058

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CYB5B expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of CYB5B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CYB5B 80777 8 1 21
GSE20123 CYB5B 80777 8 1 21
GSE43470 CYB5B 80777 2 6 35
GSE46452 CYB5B 80777 38 1 20
GSE47630 CYB5B 80777 11 8 21
GSE54993 CYB5B 80777 2 4 64
GSE54994 CYB5B 80777 8 9 36
GSE60625 CYB5B 80777 4 0 7
GSE74703 CYB5B 80777 2 3 31
GSE74704 CYB5B 80777 4 0 16
TCGA CYB5B 80777 28 12 56

Total number of gains: 115; Total number of losses: 45; Total Number of normals: 328.  

 

Somatic mutations of CYB5B:

 

Generating mutation plots.

 

Highly correlated genes for CYB5B:

 

Showing top 20/506 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CYB5BCRYZ0.743072303
CYB5BCMC10.742666303
CYB5BSTRAP0.73082303
CYB5BMRPS270.726533303
CYB5BSTX40.719915303
CYB5BTHAP20.71403303
CYB5BMRPL90.713406303
CYB5BNDUFV10.699351403
CYB5BIMPDH20.698485303
CYB5BACO20.698263303
CYB5BMRPL330.689885303
CYB5BRNF144B0.684902303
CYB5BSENP20.682104404
CYB5BSLC38A70.680479303
CYB5BMRPS70.674554504
CYB5BRSPRY10.673475504
CYB5BTACO10.672212505
CYB5BMITD10.671144403
CYB5BHSPA40.667466303
CYB5BZC3H180.66592303

For details and further investigation, click here