| Full name: HLA complex group 4 | Alias Symbol: HCGIV-10|HCGIV.9 | ||
| Type: non-coding RNA | Cytoband: 6p22.1 | ||
| Entrez ID: 54435 | HGNC ID: HGNC:21241 | Ensembl Gene: ENSG00000176998 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HCG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HCG4 | 54435 | 206685_at | 0.5829 | 0.6357 | |
| GSE20347 | HCG4 | 54435 | 206685_at | -0.0363 | 0.8920 | |
| GSE23400 | HCG4 | 54435 | 206685_at | 0.0243 | 0.6475 | |
| GSE26886 | HCG4 | 54435 | 206685_at | 0.4086 | 0.4047 | |
| GSE29001 | HCG4 | 54435 | 206685_at | 0.3332 | 0.3237 | |
| GSE38129 | HCG4 | 54435 | 206685_at | 0.2519 | 0.3565 | |
| GSE45670 | HCG4 | 54435 | 206685_at | 0.6304 | 0.1684 | |
| GSE63941 | HCG4 | 54435 | 206685_at | 1.4385 | 0.2391 | |
| GSE77861 | HCG4 | 54435 | 206685_at | 0.0448 | 0.8670 | |
| SRP007169 | HCG4 | 54435 | RNAseq | -1.3633 | 0.0383 | |
| SRP064894 | HCG4 | 54435 | RNAseq | 0.3423 | 0.3714 | |
| SRP133303 | HCG4 | 54435 | RNAseq | 0.4907 | 0.1834 | |
| SRP159526 | HCG4 | 54435 | RNAseq | 0.4710 | 0.5369 | |
| SRP219564 | HCG4 | 54435 | RNAseq | 0.3176 | 0.7561 | |
| TCGA | HCG4 | 54435 | RNAseq | 0.6245 | 0.0594 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HCG4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HCG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HCG4 | 54435 | 2 | 1 | 27 | |
| GSE20123 | HCG4 | 54435 | 2 | 1 | 27 | |
| GSE43470 | HCG4 | 54435 | 5 | 0 | 38 | |
| GSE46452 | HCG4 | 54435 | 1 | 10 | 48 | |
| GSE47630 | HCG4 | 54435 | 7 | 4 | 29 | |
| GSE54993 | HCG4 | 54435 | 2 | 1 | 67 | |
| GSE54994 | HCG4 | 54435 | 11 | 4 | 38 | |
| GSE60625 | HCG4 | 54435 | 0 | 1 | 10 | |
| GSE74703 | HCG4 | 54435 | 5 | 0 | 31 | |
| GSE74704 | HCG4 | 54435 | 0 | 0 | 20 |
Total number of gains: 35; Total number of losses: 22; Total Number of normals: 335.
Somatic mutations of HCG4:
Generating mutation plots.
Highly correlated genes for HCG4:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HCG4 | CYP26B1 | 0.686039 | 3 | 0 | 3 |
| HCG4 | LINC00460 | 0.619953 | 3 | 0 | 3 |
| HCG4 | ASH1L-AS1 | 0.617859 | 4 | 0 | 3 |
| HCG4 | PDPN | 0.606626 | 3 | 0 | 3 |
| HCG4 | NEURL3 | 0.595168 | 3 | 0 | 3 |
| HCG4 | KANK4 | 0.590128 | 3 | 0 | 3 |
| HCG4 | NUDT21 | 0.583426 | 4 | 0 | 3 |
| HCG4 | HRH1 | 0.581945 | 3 | 0 | 3 |
| HCG4 | LINC01121 | 0.575147 | 4 | 0 | 3 |
| HCG4 | ESM1 | 0.569215 | 3 | 0 | 3 |
| HCG4 | CIAPIN1 | 0.555632 | 5 | 0 | 3 |
| HCG4 | DNAJA2 | 0.551525 | 3 | 0 | 3 |
| HCG4 | TMEM45A | 0.550484 | 4 | 0 | 3 |
| HCG4 | ELMSAN1 | 0.545243 | 4 | 0 | 3 |
| HCG4 | CDSN | 0.54442 | 5 | 0 | 3 |
| HCG4 | PSMA5 | 0.538374 | 4 | 0 | 3 |
| HCG4 | LPAR3 | 0.537881 | 5 | 0 | 3 |
| HCG4 | ABCA12 | 0.530831 | 5 | 0 | 3 |
| HCG4 | SERINC3 | 0.530664 | 6 | 0 | 3 |
| HCG4 | SERPINB7 | 0.53011 | 5 | 0 | 3 |
For details and further investigation, click here
