| Full name: prolyl endopeptidase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 5550 | HGNC ID: HGNC:9358 | Ensembl Gene: ENSG00000085377 | OMIM ID: 600400 |
| Drug and gene relationship at DGIdb | |||
Expression of PREP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PREP | 5550 | 204117_at | 0.1708 | 0.5576 | |
| GSE20347 | PREP | 5550 | 204117_at | 0.2002 | 0.1464 | |
| GSE23400 | PREP | 5550 | 204117_at | 0.2073 | 0.0003 | |
| GSE26886 | PREP | 5550 | 204117_at | -0.1908 | 0.1476 | |
| GSE29001 | PREP | 5550 | 204117_at | 0.0395 | 0.8695 | |
| GSE38129 | PREP | 5550 | 204117_at | 0.2327 | 0.0206 | |
| GSE45670 | PREP | 5550 | 204117_at | 0.2845 | 0.0114 | |
| GSE53622 | PREP | 5550 | 104341 | 0.1627 | 0.0191 | |
| GSE53624 | PREP | 5550 | 104341 | 0.1487 | 0.1022 | |
| GSE63941 | PREP | 5550 | 204117_at | -0.0356 | 0.9438 | |
| GSE77861 | PREP | 5550 | 204117_at | 0.2630 | 0.2202 | |
| GSE97050 | PREP | 5550 | A_33_P3230976 | 0.5418 | 0.1523 | |
| SRP007169 | PREP | 5550 | RNAseq | 0.6079 | 0.0744 | |
| SRP008496 | PREP | 5550 | RNAseq | 0.8166 | 0.0066 | |
| SRP064894 | PREP | 5550 | RNAseq | 0.2203 | 0.1300 | |
| SRP133303 | PREP | 5550 | RNAseq | 0.3781 | 0.0167 | |
| SRP159526 | PREP | 5550 | RNAseq | 0.1209 | 0.4776 | |
| SRP193095 | PREP | 5550 | RNAseq | 0.0265 | 0.8493 | |
| SRP219564 | PREP | 5550 | RNAseq | -0.0766 | 0.7492 | |
| TCGA | PREP | 5550 | RNAseq | 0.0498 | 0.3358 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PREP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PREP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PREP | 5550 | 3 | 3 | 24 | |
| GSE20123 | PREP | 5550 | 3 | 2 | 25 | |
| GSE43470 | PREP | 5550 | 3 | 1 | 39 | |
| GSE46452 | PREP | 5550 | 2 | 11 | 46 | |
| GSE47630 | PREP | 5550 | 8 | 5 | 27 | |
| GSE54993 | PREP | 5550 | 3 | 2 | 65 | |
| GSE54994 | PREP | 5550 | 8 | 8 | 37 | |
| GSE60625 | PREP | 5550 | 0 | 2 | 9 | |
| GSE74703 | PREP | 5550 | 2 | 1 | 33 | |
| GSE74704 | PREP | 5550 | 1 | 0 | 19 | |
| TCGA | PREP | 5550 | 6 | 25 | 65 |
Total number of gains: 39; Total number of losses: 60; Total Number of normals: 389.
Somatic mutations of PREP:
Generating mutation plots.
Highly correlated genes for PREP:
Showing top 20/307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PREP | WDR54 | 0.767432 | 3 | 0 | 3 |
| PREP | NAA15 | 0.718131 | 3 | 0 | 3 |
| PREP | TNNT1 | 0.708901 | 3 | 0 | 3 |
| PREP | IMMP1L | 0.70855 | 3 | 0 | 3 |
| PREP | CYP26B1 | 0.682763 | 4 | 0 | 3 |
| PREP | EFTUD2 | 0.678164 | 4 | 0 | 4 |
| PREP | CRLF3 | 0.669072 | 3 | 0 | 3 |
| PREP | C20orf27 | 0.667797 | 3 | 0 | 3 |
| PREP | MRPL35 | 0.66663 | 4 | 0 | 3 |
| PREP | MEF2A | 0.664904 | 4 | 0 | 3 |
| PREP | CXXC5 | 0.663961 | 3 | 0 | 3 |
| PREP | BCKDK | 0.662813 | 4 | 0 | 3 |
| PREP | NRBF2 | 0.661141 | 3 | 0 | 3 |
| PREP | CHMP1B | 0.652454 | 3 | 0 | 3 |
| PREP | AJUBA | 0.650632 | 6 | 0 | 4 |
| PREP | TRAP1 | 0.648094 | 4 | 0 | 3 |
| PREP | RPS6KC1 | 0.646616 | 3 | 0 | 3 |
| PREP | POLR1C | 0.6459 | 4 | 0 | 3 |
| PREP | TMEM54 | 0.645612 | 4 | 0 | 3 |
| PREP | FANCM | 0.644484 | 4 | 0 | 3 |
For details and further investigation, click here
