| Full name: glutathione S-transferase alpha 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.2 | ||
| Entrez ID: 2941 | HGNC ID: HGNC:4629 | Ensembl Gene: ENSG00000170899 | OMIM ID: 605450 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTA4 | 2941 | 202967_at | -0.3379 | 0.3798 | |
| GSE20347 | GSTA4 | 2941 | 202967_at | -0.8017 | 0.0546 | |
| GSE23400 | GSTA4 | 2941 | 202967_at | -0.2242 | 0.1979 | |
| GSE26886 | GSTA4 | 2941 | 202967_at | -1.2756 | 0.0050 | |
| GSE29001 | GSTA4 | 2941 | 202967_at | -0.7919 | 0.0433 | |
| GSE38129 | GSTA4 | 2941 | 202967_at | -0.4268 | 0.1831 | |
| GSE45670 | GSTA4 | 2941 | 202967_at | -0.1059 | 0.7586 | |
| GSE53622 | GSTA4 | 2941 | 129862 | -0.5475 | 0.0003 | |
| GSE53624 | GSTA4 | 2941 | 129862 | -0.6935 | 0.0000 | |
| GSE63941 | GSTA4 | 2941 | 202967_at | -1.0020 | 0.5435 | |
| GSE77861 | GSTA4 | 2941 | 202967_at | 0.2763 | 0.6492 | |
| GSE97050 | GSTA4 | 2941 | A_33_P3257903 | -0.6217 | 0.1065 | |
| SRP007169 | GSTA4 | 2941 | RNAseq | -1.0548 | 0.0859 | |
| SRP008496 | GSTA4 | 2941 | RNAseq | -0.5688 | 0.1564 | |
| SRP064894 | GSTA4 | 2941 | RNAseq | -0.9813 | 0.0000 | |
| SRP133303 | GSTA4 | 2941 | RNAseq | -0.6521 | 0.0563 | |
| SRP159526 | GSTA4 | 2941 | RNAseq | 0.0039 | 0.9923 | |
| SRP193095 | GSTA4 | 2941 | RNAseq | -1.2085 | 0.0000 | |
| SRP219564 | GSTA4 | 2941 | RNAseq | -0.4343 | 0.5131 | |
| TCGA | GSTA4 | 2941 | RNAseq | -0.1268 | 0.3173 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GSTA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTA4 | 2941 | 7 | 2 | 21 | |
| GSE20123 | GSTA4 | 2941 | 7 | 2 | 21 | |
| GSE43470 | GSTA4 | 2941 | 5 | 0 | 38 | |
| GSE46452 | GSTA4 | 2941 | 2 | 10 | 47 | |
| GSE47630 | GSTA4 | 2941 | 7 | 5 | 28 | |
| GSE54993 | GSTA4 | 2941 | 3 | 1 | 66 | |
| GSE54994 | GSTA4 | 2941 | 8 | 4 | 41 | |
| GSE60625 | GSTA4 | 2941 | 0 | 3 | 8 | |
| GSE74703 | GSTA4 | 2941 | 5 | 0 | 31 | |
| GSE74704 | GSTA4 | 2941 | 3 | 1 | 16 | |
| TCGA | GSTA4 | 2941 | 22 | 12 | 62 |
Total number of gains: 69; Total number of losses: 40; Total Number of normals: 379.
Somatic mutations of GSTA4:
Generating mutation plots.
Highly correlated genes for GSTA4:
Showing top 20/282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTA4 | PEX2 | 0.715414 | 3 | 0 | 3 |
| GSTA4 | EPG5 | 0.697391 | 3 | 0 | 3 |
| GSTA4 | UBE4A | 0.684501 | 3 | 0 | 3 |
| GSTA4 | PSMD10 | 0.684467 | 3 | 0 | 3 |
| GSTA4 | UBE2J1 | 0.684389 | 3 | 0 | 3 |
| GSTA4 | CYP4F3 | 0.671302 | 10 | 0 | 9 |
| GSTA4 | ABCG2 | 0.668925 | 3 | 0 | 3 |
| GSTA4 | JAK2 | 0.668776 | 3 | 0 | 3 |
| GSTA4 | SETX | 0.662881 | 3 | 0 | 3 |
| GSTA4 | PCDH19 | 0.65202 | 4 | 0 | 3 |
| GSTA4 | ALDH3A1 | 0.651262 | 12 | 0 | 11 |
| GSTA4 | CHM | 0.649373 | 3 | 0 | 3 |
| GSTA4 | PIGB | 0.643261 | 3 | 0 | 3 |
| GSTA4 | SNX1 | 0.642724 | 4 | 0 | 3 |
| GSTA4 | CCDC25 | 0.639377 | 4 | 0 | 3 |
| GSTA4 | SUPT4H1 | 0.63797 | 3 | 0 | 3 |
| GSTA4 | HBP1 | 0.63233 | 6 | 0 | 4 |
| GSTA4 | USP8 | 0.63165 | 3 | 0 | 3 |
| GSTA4 | FAM120B | 0.630894 | 3 | 0 | 3 |
| GSTA4 | ZNF175 | 0.629516 | 3 | 0 | 3 |
For details and further investigation, click here
