| Full name: cytochrome P450 family 4 subfamily F member 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 11283 | HGNC ID: HGNC:2648 | Ensembl Gene: ENSG00000186526 | OMIM ID: 611545 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP4F8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP4F8 | 11283 | 210576_at | -0.0907 | 0.7020 | |
| GSE20347 | CYP4F8 | 11283 | 210576_at | -0.0328 | 0.6301 | |
| GSE23400 | CYP4F8 | 11283 | 210576_at | -0.0194 | 0.2542 | |
| GSE26886 | CYP4F8 | 11283 | 210576_at | 0.0235 | 0.8788 | |
| GSE29001 | CYP4F8 | 11283 | 210576_at | -0.0232 | 0.8276 | |
| GSE38129 | CYP4F8 | 11283 | 210576_at | -0.0292 | 0.5642 | |
| GSE45670 | CYP4F8 | 11283 | 210576_at | 0.0131 | 0.9011 | |
| GSE53622 | CYP4F8 | 11283 | 44600 | -1.0742 | 0.0002 | |
| GSE53624 | CYP4F8 | 11283 | 44600 | -1.3666 | 0.0000 | |
| GSE63941 | CYP4F8 | 11283 | 210576_at | 0.1433 | 0.4030 | |
| GSE77861 | CYP4F8 | 11283 | 210576_at | -0.0644 | 0.7306 | |
| GSE97050 | CYP4F8 | 11283 | A_23_P131060 | -0.6975 | 0.1417 | |
| SRP133303 | CYP4F8 | 11283 | RNAseq | 0.1113 | 0.5580 | |
| SRP193095 | CYP4F8 | 11283 | RNAseq | 0.0846 | 0.6348 | |
| TCGA | CYP4F8 | 11283 | RNAseq | 0.0279 | 0.9840 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CYP4F8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP4F8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP4F8 | 11283 | 4 | 2 | 24 | |
| GSE20123 | CYP4F8 | 11283 | 3 | 1 | 26 | |
| GSE43470 | CYP4F8 | 11283 | 2 | 5 | 36 | |
| GSE46452 | CYP4F8 | 11283 | 47 | 1 | 11 | |
| GSE47630 | CYP4F8 | 11283 | 4 | 7 | 29 | |
| GSE54993 | CYP4F8 | 11283 | 15 | 4 | 51 | |
| GSE54994 | CYP4F8 | 11283 | 6 | 14 | 33 | |
| GSE60625 | CYP4F8 | 11283 | 9 | 0 | 2 | |
| GSE74703 | CYP4F8 | 11283 | 2 | 4 | 30 | |
| GSE74704 | CYP4F8 | 11283 | 0 | 1 | 19 | |
| TCGA | CYP4F8 | 11283 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of CYP4F8:
Generating mutation plots.
Highly correlated genes for CYP4F8:
Showing top 20/85 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP4F8 | CYP4F12 | 0.71222 | 5 | 0 | 4 |
| CYP4F8 | CYP4F2 | 0.700485 | 7 | 0 | 6 |
| CYP4F8 | CYP4F11 | 0.690509 | 4 | 0 | 4 |
| CYP4F8 | AKR1B15 | 0.658971 | 3 | 0 | 3 |
| CYP4F8 | ST6GALNAC1 | 0.650148 | 3 | 0 | 3 |
| CYP4F8 | CD28 | 0.649103 | 3 | 0 | 3 |
| CYP4F8 | SUSD4 | 0.635869 | 4 | 0 | 3 |
| CYP4F8 | RNF31 | 0.635661 | 3 | 0 | 3 |
| CYP4F8 | CEACAM6 | 0.63238 | 3 | 0 | 3 |
| CYP4F8 | HS3ST6 | 0.63156 | 4 | 0 | 4 |
| CYP4F8 | CXCL17 | 0.620496 | 3 | 0 | 3 |
| CYP4F8 | ADH7 | 0.619243 | 5 | 0 | 4 |
| CYP4F8 | GPR26 | 0.617889 | 4 | 0 | 3 |
| CYP4F8 | ALDH3A1 | 0.61225 | 6 | 0 | 4 |
| CYP4F8 | ABCC3 | 0.604426 | 4 | 0 | 3 |
| CYP4F8 | CA3 | 0.587205 | 3 | 0 | 3 |
| CYP4F8 | KRT33A | 0.586983 | 4 | 0 | 3 |
| CYP4F8 | MUC20 | 0.580354 | 3 | 0 | 3 |
| CYP4F8 | VWCE | 0.578298 | 4 | 0 | 3 |
| CYP4F8 | AKR1C3 | 0.574171 | 3 | 0 | 3 |
For details and further investigation, click here
