CYP4F11

 

Full name: cytochrome P450 family 4 subfamily F member 11 Alias Symbol: 
Type: protein-coding gene Cytoband: 19p13.12
Entrez ID: 57834 HGNC ID: HGNC:13265 Ensembl Gene: ENSG00000171903 OMIM ID: 611517
Drug and gene relationship at DGIdb

 

Expression of CYP4F11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CYP4F11 57834 206153_at -0.5399 0.7739
GSE20347 CYP4F11 57834 206153_at 0.7934 0.1639
GSE23400 CYP4F11 57834 206153_at 0.7011 0.0077
GSE26886 CYP4F11 57834 206153_at 1.2336 0.0257
GSE29001 CYP4F11 57834 206153_at -0.2359 0.2642
GSE38129 CYP4F11 57834 206153_at 1.0827 0.0177
GSE45670 CYP4F11 57834 206153_at 0.8342 0.1574
GSE53622 CYP4F11 57834 87537 0.2304 0.6304
GSE53624 CYP4F11 57834 106668 0.0341 0.9127
GSE63941 CYP4F11 57834 206153_at 2.4534 0.1127
GSE77861 CYP4F11 57834 206153_at 0.9015 0.3384
SRP007169 CYP4F11 57834 RNAseq 2.1430 0.0203
SRP008496 CYP4F11 57834 RNAseq 1.4823 0.1172
SRP064894 CYP4F11 57834 RNAseq -0.3404 0.5706
SRP133303 CYP4F11 57834 RNAseq -0.1974 0.6238
SRP159526 CYP4F11 57834 RNAseq 2.3057 0.0330
SRP219564 CYP4F11 57834 RNAseq 0.3918 0.7354
TCGA CYP4F11 57834 RNAseq 0.8188 0.0409

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by CYP4F11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CYP4F11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CYP4F11 57834 4 2 24
GSE20123 CYP4F11 57834 3 1 26
GSE43470 CYP4F11 57834 2 6 35
GSE46452 CYP4F11 57834 47 1 11
GSE47630 CYP4F11 57834 4 8 28
GSE54993 CYP4F11 57834 15 4 51
GSE54994 CYP4F11 57834 6 14 33
GSE60625 CYP4F11 57834 9 0 2
GSE74703 CYP4F11 57834 2 4 30
GSE74704 CYP4F11 57834 0 1 19
TCGA CYP4F11 57834 18 12 66

Total number of gains: 110; Total number of losses: 53; Total Number of normals: 325.  

 

Somatic mutations of CYP4F11:

 

Generating mutation plots.

 

Highly correlated genes for CYP4F11:

 

Showing top 20/133 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CYP4F11G6PD0.72996611011
CYP4F11CYP4F20.71301612012
CYP4F11AKR1C30.69835311010
CYP4F11CYP4F80.690509404
CYP4F11OSGIN10.67240312011
CYP4F11ADAM230.6697061008
CYP4F11SRXN10.65094606
CYP4F11SOST0.644024807
CYP4F11AKR1C10.6394951109
CYP4F11SLC7A110.6385331209
CYP4F11AKR1C20.6378921008
CYP4F11CYP4F30.6313991209
CYP4F11AKR1B150.629044303
CYP4F11TXNRD10.6251191007
CYP4F11ABCB60.625111909
CYP4F11CLDN200.624638503
CYP4F11ABCC10.623751008
CYP4F11GLI20.621708806
CYP4F11ABCC30.61917212010
CYP4F11AKR1B100.61704511010

For details and further investigation, click here