| Full name: cadherin EGF LAG seven-pass G-type receptor 1 | Alias Symbol: ME2|HFMI2|FMI2|CDHF9|ADGRC1 | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 9620 | HGNC ID: HGNC:1850 | Ensembl Gene: ENSG00000075275 | OMIM ID: 604523 |
| Drug and gene relationship at DGIdb | |||
Expression of CELSR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CELSR1 | 9620 | 41660_at | 0.9002 | 0.2929 | |
| GSE20347 | CELSR1 | 9620 | 41660_at | -0.2077 | 0.3480 | |
| GSE23400 | CELSR1 | 9620 | 41660_at | 0.2381 | 0.0103 | |
| GSE26886 | CELSR1 | 9620 | 41660_at | 0.2133 | 0.2551 | |
| GSE29001 | CELSR1 | 9620 | 41660_at | -0.1719 | 0.6127 | |
| GSE38129 | CELSR1 | 9620 | 41660_at | 0.4679 | 0.1347 | |
| GSE45670 | CELSR1 | 9620 | 41660_at | 0.7732 | 0.0002 | |
| GSE53622 | CELSR1 | 9620 | 47146 | -0.1918 | 0.0002 | |
| GSE53624 | CELSR1 | 9620 | 47146 | -0.0131 | 0.7494 | |
| GSE63941 | CELSR1 | 9620 | 41660_at | 3.0659 | 0.0011 | |
| GSE77861 | CELSR1 | 9620 | 41660_at | 0.5094 | 0.0460 | |
| GSE97050 | CELSR1 | 9620 | A_33_P3328659 | 0.1142 | 0.6411 | |
| SRP007169 | CELSR1 | 9620 | RNAseq | 0.7273 | 0.0352 | |
| SRP008496 | CELSR1 | 9620 | RNAseq | 0.2604 | 0.2684 | |
| SRP064894 | CELSR1 | 9620 | RNAseq | 0.4726 | 0.1800 | |
| SRP133303 | CELSR1 | 9620 | RNAseq | 0.5686 | 0.0121 | |
| SRP159526 | CELSR1 | 9620 | RNAseq | 0.3939 | 0.2987 | |
| SRP193095 | CELSR1 | 9620 | RNAseq | 0.5931 | 0.0195 | |
| TCGA | CELSR1 | 9620 | RNAseq | 0.3722 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CELSR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CELSR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CELSR1 | 9620 | 5 | 6 | 19 | |
| GSE20123 | CELSR1 | 9620 | 4 | 5 | 21 | |
| GSE43470 | CELSR1 | 9620 | 2 | 6 | 35 | |
| GSE46452 | CELSR1 | 9620 | 31 | 2 | 26 | |
| GSE47630 | CELSR1 | 9620 | 9 | 4 | 27 | |
| GSE54993 | CELSR1 | 9620 | 3 | 6 | 61 | |
| GSE54994 | CELSR1 | 9620 | 11 | 7 | 35 | |
| GSE60625 | CELSR1 | 9620 | 5 | 0 | 6 | |
| GSE74703 | CELSR1 | 9620 | 2 | 4 | 30 | |
| GSE74704 | CELSR1 | 9620 | 2 | 3 | 15 | |
| TCGA | CELSR1 | 9620 | 27 | 17 | 52 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of CELSR1:
Generating mutation plots.
Highly correlated genes for CELSR1:
Showing top 20/616 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CELSR1 | SOX13 | 0.715807 | 3 | 0 | 3 |
| CELSR1 | PSMD9 | 0.708478 | 3 | 0 | 3 |
| CELSR1 | IAH1 | 0.706164 | 4 | 0 | 4 |
| CELSR1 | AMMECR1L | 0.69883 | 3 | 0 | 3 |
| CELSR1 | MCCC2 | 0.695158 | 3 | 0 | 3 |
| CELSR1 | HMG20B | 0.686603 | 4 | 0 | 4 |
| CELSR1 | TERF2 | 0.678712 | 3 | 0 | 3 |
| CELSR1 | EPPK1 | 0.678649 | 4 | 0 | 4 |
| CELSR1 | ASCC1 | 0.67696 | 3 | 0 | 3 |
| CELSR1 | PPP1R14C | 0.675814 | 4 | 0 | 4 |
| CELSR1 | DHPS | 0.673869 | 3 | 0 | 3 |
| CELSR1 | PPP1R13L | 0.670067 | 3 | 0 | 3 |
| CELSR1 | CPT1A | 0.668621 | 3 | 0 | 3 |
| CELSR1 | POLG | 0.667863 | 3 | 0 | 3 |
| CELSR1 | TPM3 | 0.660049 | 4 | 0 | 3 |
| CELSR1 | SLC39A10 | 0.659524 | 3 | 0 | 3 |
| CELSR1 | DAGLB | 0.655892 | 4 | 0 | 3 |
| CELSR1 | ZNF317 | 0.655498 | 3 | 0 | 3 |
| CELSR1 | DOLK | 0.652488 | 4 | 0 | 3 |
| CELSR1 | NASP | 0.652467 | 4 | 0 | 3 |
For details and further investigation, click here
