| Full name: tumor protein D52 | Alias Symbol: D52|hD52|N8L | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 7163 | HGNC ID: HGNC:12005 | Ensembl Gene: ENSG00000076554 | OMIM ID: 604068 |
| Drug and gene relationship at DGIdb | |||
Expression of TPD52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPD52 | 7163 | 201690_s_at | 0.2814 | 0.4861 | |
| GSE20347 | TPD52 | 7163 | 201690_s_at | 0.2178 | 0.3262 | |
| GSE23400 | TPD52 | 7163 | 201690_s_at | 0.2080 | 0.0872 | |
| GSE26886 | TPD52 | 7163 | 201690_s_at | -0.5233 | 0.0127 | |
| GSE29001 | TPD52 | 7163 | 201690_s_at | 0.0372 | 0.9078 | |
| GSE38129 | TPD52 | 7163 | 201690_s_at | 0.4284 | 0.0206 | |
| GSE45670 | TPD52 | 7163 | 201690_s_at | 0.1905 | 0.3800 | |
| GSE53622 | TPD52 | 7163 | 37291 | -0.2882 | 0.0070 | |
| GSE53624 | TPD52 | 7163 | 37291 | -0.2404 | 0.0163 | |
| GSE63941 | TPD52 | 7163 | 201690_s_at | 6.8924 | 0.0000 | |
| GSE77861 | TPD52 | 7163 | 201690_s_at | 0.1258 | 0.6178 | |
| GSE97050 | TPD52 | 7163 | A_33_P3347971 | -0.1684 | 0.6594 | |
| SRP007169 | TPD52 | 7163 | RNAseq | 0.4464 | 0.2818 | |
| SRP008496 | TPD52 | 7163 | RNAseq | 0.4127 | 0.0864 | |
| SRP064894 | TPD52 | 7163 | RNAseq | -0.0655 | 0.8272 | |
| SRP133303 | TPD52 | 7163 | RNAseq | 0.2980 | 0.2683 | |
| SRP159526 | TPD52 | 7163 | RNAseq | -0.2142 | 0.5914 | |
| SRP193095 | TPD52 | 7163 | RNAseq | -0.7594 | 0.0006 | |
| SRP219564 | TPD52 | 7163 | RNAseq | -0.0870 | 0.8501 | |
| TCGA | TPD52 | 7163 | RNAseq | -0.0808 | 0.1739 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TPD52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPD52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPD52 | 7163 | 16 | 1 | 13 | |
| GSE20123 | TPD52 | 7163 | 18 | 1 | 11 | |
| GSE43470 | TPD52 | 7163 | 18 | 1 | 24 | |
| GSE46452 | TPD52 | 7163 | 21 | 0 | 38 | |
| GSE47630 | TPD52 | 7163 | 23 | 0 | 17 | |
| GSE54993 | TPD52 | 7163 | 0 | 19 | 51 | |
| GSE54994 | TPD52 | 7163 | 30 | 0 | 23 | |
| GSE60625 | TPD52 | 7163 | 0 | 4 | 7 | |
| GSE74703 | TPD52 | 7163 | 15 | 1 | 20 | |
| GSE74704 | TPD52 | 7163 | 12 | 0 | 8 | |
| TCGA | TPD52 | 7163 | 50 | 3 | 43 |
Total number of gains: 203; Total number of losses: 30; Total Number of normals: 255.
Somatic mutations of TPD52:
Generating mutation plots.
Highly correlated genes for TPD52:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPD52 | RPS27A | 0.803018 | 3 | 0 | 3 |
| TPD52 | DDX18 | 0.777639 | 3 | 0 | 3 |
| TPD52 | POLE3 | 0.774639 | 3 | 0 | 3 |
| TPD52 | SNRPE | 0.742717 | 3 | 0 | 3 |
| TPD52 | CLK2 | 0.72415 | 3 | 0 | 3 |
| TPD52 | ASXL2 | 0.702325 | 4 | 0 | 3 |
| TPD52 | TPRKB | 0.701781 | 4 | 0 | 3 |
| TPD52 | TMEM69 | 0.700765 | 3 | 0 | 3 |
| TPD52 | RNF126 | 0.700579 | 3 | 0 | 3 |
| TPD52 | ZNF664 | 0.694273 | 3 | 0 | 3 |
| TPD52 | PSMB1 | 0.691741 | 3 | 0 | 3 |
| TPD52 | WNK1 | 0.690174 | 3 | 0 | 3 |
| TPD52 | CLYBL | 0.689058 | 3 | 0 | 3 |
| TPD52 | EXOSC10 | 0.68687 | 4 | 0 | 4 |
| TPD52 | NUDT21 | 0.686388 | 4 | 0 | 4 |
| TPD52 | STX17 | 0.685025 | 3 | 0 | 3 |
| TPD52 | PPP2R3C | 0.684163 | 3 | 0 | 3 |
| TPD52 | DAGLB | 0.681714 | 3 | 0 | 3 |
| TPD52 | TP53RK | 0.679789 | 4 | 0 | 3 |
| TPD52 | SRP9 | 0.679306 | 4 | 0 | 4 |
For details and further investigation, click here
