| Full name: solute carrier family 39 member 4 | Alias Symbol: ZIP4|AWMS2 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 55630 | HGNC ID: HGNC:17129 | Ensembl Gene: ENSG00000147804 | OMIM ID: 607059 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC39A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A4 | 55630 | 219215_s_at | 1.7597 | 0.0591 | |
| GSE20347 | SLC39A4 | 55630 | 219215_s_at | 0.8798 | 0.0000 | |
| GSE23400 | SLC39A4 | 55630 | 219215_s_at | 0.7576 | 0.0000 | |
| GSE26886 | SLC39A4 | 55630 | 219215_s_at | 1.7670 | 0.0000 | |
| GSE29001 | SLC39A4 | 55630 | 219215_s_at | 0.4253 | 0.3107 | |
| GSE38129 | SLC39A4 | 55630 | 219215_s_at | 1.1632 | 0.0000 | |
| GSE45670 | SLC39A4 | 55630 | 219215_s_at | 1.0609 | 0.0001 | |
| GSE53622 | SLC39A4 | 55630 | 44993 | 0.9749 | 0.0000 | |
| GSE53624 | SLC39A4 | 55630 | 44993 | 0.8800 | 0.0000 | |
| GSE63941 | SLC39A4 | 55630 | 219215_s_at | 2.2776 | 0.0243 | |
| GSE77861 | SLC39A4 | 55630 | 219215_s_at | 0.9622 | 0.0867 | |
| GSE97050 | SLC39A4 | 55630 | A_33_P3240353 | 0.8330 | 0.1189 | |
| SRP007169 | SLC39A4 | 55630 | RNAseq | 0.6774 | 0.3295 | |
| SRP064894 | SLC39A4 | 55630 | RNAseq | 1.7523 | 0.0000 | |
| SRP133303 | SLC39A4 | 55630 | RNAseq | 0.7258 | 0.0005 | |
| SRP159526 | SLC39A4 | 55630 | RNAseq | 1.1207 | 0.0243 | |
| SRP193095 | SLC39A4 | 55630 | RNAseq | 0.1268 | 0.6204 | |
| SRP219564 | SLC39A4 | 55630 | RNAseq | 1.1729 | 0.0358 | |
| TCGA | SLC39A4 | 55630 | RNAseq | 0.3417 | 0.0017 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by SLC39A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A4 | 55630 | 17 | 1 | 12 | |
| GSE20123 | SLC39A4 | 55630 | 17 | 1 | 12 | |
| GSE43470 | SLC39A4 | 55630 | 16 | 2 | 25 | |
| GSE46452 | SLC39A4 | 55630 | 28 | 0 | 31 | |
| GSE47630 | SLC39A4 | 55630 | 25 | 1 | 14 | |
| GSE54993 | SLC39A4 | 55630 | 0 | 25 | 45 | |
| GSE54994 | SLC39A4 | 55630 | 39 | 1 | 13 | |
| GSE60625 | SLC39A4 | 55630 | 3 | 4 | 4 | |
| GSE74703 | SLC39A4 | 55630 | 14 | 1 | 21 | |
| GSE74704 | SLC39A4 | 55630 | 10 | 0 | 10 | |
| TCGA | SLC39A4 | 55630 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of SLC39A4:
Generating mutation plots.
Highly correlated genes for SLC39A4:
Showing top 20/1393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A4 | SLC52A2 | 0.785902 | 10 | 0 | 10 |
| SLC39A4 | BOP1 | 0.74726 | 3 | 0 | 3 |
| SLC39A4 | WDR66 | 0.737236 | 8 | 0 | 8 |
| SLC39A4 | MTERF3 | 0.722814 | 7 | 0 | 7 |
| SLC39A4 | POLR1A | 0.722288 | 3 | 0 | 3 |
| SLC39A4 | SLC39A3 | 0.718135 | 3 | 0 | 3 |
| SLC39A4 | DBF4B | 0.716689 | 3 | 0 | 3 |
| SLC39A4 | DNAJB11 | 0.710368 | 5 | 0 | 5 |
| SLC39A4 | GNPNAT1 | 0.706332 | 4 | 0 | 4 |
| SLC39A4 | KIF20A | 0.704736 | 10 | 0 | 9 |
| SLC39A4 | RTKN | 0.702481 | 7 | 0 | 7 |
| SLC39A4 | CEP55 | 0.701442 | 9 | 0 | 9 |
| SLC39A4 | ATAD2 | 0.698827 | 10 | 0 | 10 |
| SLC39A4 | PUF60 | 0.697538 | 10 | 0 | 9 |
| SLC39A4 | YWHAG | 0.696419 | 4 | 0 | 4 |
| SLC39A4 | CENPF | 0.696014 | 10 | 0 | 10 |
| SLC39A4 | C19orf48 | 0.694289 | 3 | 0 | 3 |
| SLC39A4 | MYBL2 | 0.694122 | 11 | 0 | 11 |
| SLC39A4 | ERVMER34-1 | 0.689215 | 10 | 0 | 10 |
| SLC39A4 | FBRSL1 | 0.688587 | 4 | 0 | 4 |
For details and further investigation, click here
