Full name: diazepam binding inhibitor, acyl-CoA binding protein	Alias Symbol: ACBP|ACBD1
Type: protein-coding gene	Cytoband: 2q14.2
Entrez ID: 1622	HGNC ID: HGNC:2690	Ensembl Gene: ENSG00000155368	OMIM ID: 125950
Drug and gene relationship at DGIdb

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DBI involved pathways:

KEGG pathway	Description	View
hsa03320	PPAR signaling pathway	View

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Expression of DBI:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	DBI	1622	202428_x_at	0.0024	0.9979	Show
GSE20347	DBI	1622	202428_x_at	-0.5857	0.0002	Show
GSE23400	DBI	1622	202428_x_at	-0.4629	0.0002	Show
GSE26886	DBI	1622	202428_x_at	-0.7506	0.0000	Show
GSE29001	DBI	1622	202428_x_at	-0.4075	0.0048	Show
GSE38129	DBI	1622	202428_x_at	-0.1564	0.4631	Show
GSE45670	DBI	1622	202428_x_at	-0.1018	0.6000	Show
GSE53622	DBI	1622	8580	-0.9079	0.0000	Show
GSE53624	DBI	1622	8580	-0.5608	0.0000	Show
GSE63941	DBI	1622	202428_x_at	-0.2167	0.7073	Show
GSE77861	DBI	1622	202428_x_at	-0.3900	0.1708	Show
GSE97050	DBI	1622	A_33_P3244931	-0.4483	0.2462	Show
SRP007169	DBI	1622	RNAseq	-1.4882	0.0010	Show
SRP008496	DBI	1622	RNAseq	-1.3621	0.0000	Show
SRP064894	DBI	1622	RNAseq	-1.0497	0.0000	Show
SRP133303	DBI	1622	RNAseq	-0.6575	0.0393	Show
SRP159526	DBI	1622	RNAseq	-0.9014	0.0127	Show
SRP193095	DBI	1622	RNAseq	-1.4483	0.0000	Show
SRP219564	DBI	1622	RNAseq	-1.8462	0.0014	Show
TCGA	DBI	1622	RNAseq	0.2261	0.0027	Show

Upregulated datasets: 0; Downregulated datasets: 5.  Download Data

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Survival by DBI expression:

 

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Copy number change of DBI:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	DBI	1622	6	1	23	Show
GSE20123	DBI	1622	6	1	23	Show
GSE43470	DBI	1622	3	1	39	Show
GSE46452	DBI	1622	1	4	54	Show
GSE47630	DBI	1622	6	0	34	Show
GSE54993	DBI	1622	0	6	64	Show
GSE54994	DBI	1622	11	0	42	Show
GSE60625	DBI	1622	0	3	8	Show
GSE74703	DBI	1622	3	1	32	Show
GSE74704	DBI	1622	3	1	16	Show
TCGA	DBI	1622	32	6	58	Show

Total number of gains: 71; Total number of losses: 24; Total Number of normals: 393.  Download Data

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Somatic mutations of DBI:

 

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Highly correlated genes for DBI:

 

Showing top 20/1002 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
DBI	CNFN	0.752441	5	0	5
DBI	TMEM79	0.752135	5	0	5
DBI	CAPN14	0.742407	4	0	4
DBI	NCCRP1	0.742131	3	0	3
DBI	RAB3D	0.721363	6	0	6
DBI	UPK3B	0.719584	3	0	3
DBI	PGD	0.718869	11	0	10
DBI	A2ML1	0.71836	6	0	5
DBI	TMEM154	0.71644	5	0	5
DBI	NFYC	0.714374	3	0	3
DBI	RAB10	0.710048	6	0	5
DBI	SPAG17	0.707481	4	0	3
DBI	TMEM40	0.706459	9	0	9
DBI	SLC25A41	0.705379	3	0	3
DBI	CSTA	0.704244	8	0	8
DBI	FAM3D	0.702078	6	0	5
DBI	BNIPL	0.69863	6	0	5
DBI	SPINK5	0.696071	9	0	8
DBI	HS3ST6	0.694492	5	0	4
DBI	PPL	0.693697	10	0	9

For details and further investigation, click here