| Full name: solute carrier family 25 member 15 | Alias Symbol: ORC1|D13S327 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 10166 | HGNC ID: HGNC:10985 | Ensembl Gene: ENSG00000102743 | OMIM ID: 603861 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC25A15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A15 | 10166 | 218653_at | 1.0320 | 0.0347 | |
| GSE20347 | SLC25A15 | 10166 | 218653_at | 0.3914 | 0.0025 | |
| GSE23400 | SLC25A15 | 10166 | 218653_at | 0.2617 | 0.0000 | |
| GSE26886 | SLC25A15 | 10166 | 218653_at | 0.1240 | 0.5977 | |
| GSE29001 | SLC25A15 | 10166 | 218653_at | 0.1919 | 0.2699 | |
| GSE38129 | SLC25A15 | 10166 | 218653_at | 0.5366 | 0.0000 | |
| GSE45670 | SLC25A15 | 10166 | 218653_at | 0.3757 | 0.0321 | |
| GSE53622 | SLC25A15 | 10166 | 5733 | 0.7914 | 0.0000 | |
| GSE53624 | SLC25A15 | 10166 | 5733 | 0.8065 | 0.0000 | |
| GSE63941 | SLC25A15 | 10166 | 218653_at | -0.2336 | 0.7204 | |
| GSE77861 | SLC25A15 | 10166 | 218653_at | 0.4246 | 0.0618 | |
| GSE97050 | SLC25A15 | 10166 | A_33_P3840512 | 0.7425 | 0.1590 | |
| SRP007169 | SLC25A15 | 10166 | RNAseq | 0.1278 | 0.7661 | |
| SRP008496 | SLC25A15 | 10166 | RNAseq | 0.2050 | 0.4841 | |
| SRP064894 | SLC25A15 | 10166 | RNAseq | 0.4644 | 0.0092 | |
| SRP133303 | SLC25A15 | 10166 | RNAseq | -0.0383 | 0.8376 | |
| SRP159526 | SLC25A15 | 10166 | RNAseq | 0.3345 | 0.1879 | |
| SRP193095 | SLC25A15 | 10166 | RNAseq | -0.4037 | 0.0226 | |
| SRP219564 | SLC25A15 | 10166 | RNAseq | 0.2300 | 0.6372 | |
| TCGA | SLC25A15 | 10166 | RNAseq | 0.0624 | 0.4364 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC25A15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A15 | 10166 | 0 | 15 | 15 | |
| GSE20123 | SLC25A15 | 10166 | 0 | 14 | 16 | |
| GSE43470 | SLC25A15 | 10166 | 3 | 13 | 27 | |
| GSE46452 | SLC25A15 | 10166 | 0 | 33 | 26 | |
| GSE47630 | SLC25A15 | 10166 | 2 | 27 | 11 | |
| GSE54993 | SLC25A15 | 10166 | 12 | 2 | 56 | |
| GSE54994 | SLC25A15 | 10166 | 1 | 16 | 36 | |
| GSE60625 | SLC25A15 | 10166 | 0 | 3 | 8 | |
| GSE74703 | SLC25A15 | 10166 | 3 | 10 | 23 | |
| GSE74704 | SLC25A15 | 10166 | 0 | 11 | 9 | |
| TCGA | SLC25A15 | 10166 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 184; Total Number of normals: 276.
Somatic mutations of SLC25A15:
Generating mutation plots.
Highly correlated genes for SLC25A15:
Showing top 20/1436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A15 | RAPH1 | 0.780755 | 3 | 0 | 3 |
| SLC25A15 | RFC3 | 0.744132 | 10 | 0 | 8 |
| SLC25A15 | BORA | 0.733279 | 7 | 0 | 7 |
| SLC25A15 | CDCA7 | 0.727222 | 5 | 0 | 5 |
| SLC25A15 | NLN | 0.725503 | 4 | 0 | 3 |
| SLC25A15 | KIF14 | 0.724465 | 9 | 0 | 9 |
| SLC25A15 | FLVCR1 | 0.719156 | 6 | 0 | 6 |
| SLC25A15 | NUDT19 | 0.708149 | 3 | 0 | 3 |
| SLC25A15 | GEN1 | 0.70638 | 5 | 0 | 5 |
| SLC25A15 | GORAB | 0.704945 | 7 | 0 | 7 |
| SLC25A15 | MTBP | 0.70071 | 5 | 0 | 4 |
| SLC25A15 | CENPF | 0.697186 | 9 | 0 | 9 |
| SLC25A15 | ANLN | 0.693559 | 6 | 0 | 6 |
| SLC25A15 | NUF2 | 0.693498 | 7 | 0 | 6 |
| SLC25A15 | DTL | 0.68968 | 9 | 0 | 9 |
| SLC25A15 | GMNN | 0.689162 | 10 | 0 | 8 |
| SLC25A15 | SKA3 | 0.688176 | 6 | 0 | 6 |
| SLC25A15 | NEK2 | 0.687286 | 10 | 0 | 9 |
| SLC25A15 | MCMBP | 0.685306 | 3 | 0 | 3 |
| SLC25A15 | PRR11 | 0.684325 | 4 | 0 | 4 |
For details and further investigation, click here
