| Full name: defensin beta 124 | Alias Symbol: DEFB-24 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 245937 | HGNC ID: HGNC:18104 | Ensembl Gene: ENSG00000180383 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DEFB124:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEFB124 | 245937 | 1568377_x_at | 0.2817 | 0.7709 | |
| GSE26886 | DEFB124 | 245937 | 1568377_x_at | -0.6267 | 0.0329 | |
| GSE45670 | DEFB124 | 245937 | 1568377_x_at | 0.1019 | 0.5539 | |
| GSE53622 | DEFB124 | 245937 | 65049 | 0.1049 | 0.2924 | |
| GSE53624 | DEFB124 | 245937 | 65049 | -0.1725 | 0.0915 | |
| GSE63941 | DEFB124 | 245937 | 1568377_x_at | 0.1717 | 0.2139 | |
| GSE77861 | DEFB124 | 245937 | 1568377_x_at | -0.0386 | 0.9128 | |
| GSE97050 | DEFB124 | 245937 | A_33_P3316522 | -0.2374 | 0.5426 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DEFB124 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEFB124:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEFB124 | 245937 | 14 | 0 | 16 | |
| GSE20123 | DEFB124 | 245937 | 14 | 0 | 16 | |
| GSE43470 | DEFB124 | 245937 | 11 | 0 | 32 | |
| GSE46452 | DEFB124 | 245937 | 29 | 0 | 30 | |
| GSE47630 | DEFB124 | 245937 | 24 | 0 | 16 | |
| GSE54993 | DEFB124 | 245937 | 0 | 17 | 53 | |
| GSE54994 | DEFB124 | 245937 | 27 | 1 | 25 | |
| GSE60625 | DEFB124 | 245937 | 0 | 0 | 11 | |
| GSE74703 | DEFB124 | 245937 | 10 | 0 | 26 | |
| GSE74704 | DEFB124 | 245937 | 9 | 0 | 11 | |
| TCGA | DEFB124 | 245937 | 49 | 1 | 46 |
Total number of gains: 187; Total number of losses: 19; Total Number of normals: 282.
Somatic mutations of DEFB124:
Generating mutation plots.
Highly correlated genes for DEFB124:
Showing top 20/151 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEFB124 | KRTAP10-12 | 0.693507 | 3 | 0 | 3 |
| DEFB124 | PPBP | 0.688348 | 3 | 0 | 3 |
| DEFB124 | MPPED1 | 0.687145 | 4 | 0 | 4 |
| DEFB124 | GPR26 | 0.68572 | 3 | 0 | 3 |
| DEFB124 | MAG | 0.676991 | 3 | 0 | 3 |
| DEFB124 | OTOG | 0.660227 | 3 | 0 | 3 |
| DEFB124 | ISL1 | 0.657541 | 3 | 0 | 3 |
| DEFB124 | FAM131C | 0.655006 | 4 | 0 | 4 |
| DEFB124 | FAM71F1 | 0.649935 | 4 | 0 | 4 |
| DEFB124 | ST8SIA3 | 0.642367 | 4 | 0 | 4 |
| DEFB124 | KCNF1 | 0.641456 | 3 | 0 | 3 |
| DEFB124 | SLC1A7 | 0.630431 | 4 | 0 | 3 |
| DEFB124 | GHSR | 0.628932 | 4 | 0 | 3 |
| DEFB124 | YY2 | 0.627246 | 3 | 0 | 3 |
| DEFB124 | KCNK3 | 0.62714 | 4 | 0 | 4 |
| DEFB124 | IFNL2 | 0.625732 | 3 | 0 | 3 |
| DEFB124 | WDR87 | 0.625587 | 3 | 0 | 3 |
| DEFB124 | TSSK3 | 0.622111 | 4 | 0 | 4 |
| DEFB124 | STRC | 0.618311 | 3 | 0 | 3 |
| DEFB124 | GDPGP1 | 0.615342 | 4 | 0 | 3 |
For details and further investigation, click here
