| Full name: deoxyribose-phosphate aldolase | Alias Symbol: CGI-26|DEOC | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 51071 | HGNC ID: HGNC:24269 | Ensembl Gene: ENSG00000023697 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DERA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DERA | 51071 | 218102_at | -0.0365 | 0.9559 | |
| GSE20347 | DERA | 51071 | 218102_at | -0.1092 | 0.6045 | |
| GSE23400 | DERA | 51071 | 218102_at | 0.3169 | 0.0073 | |
| GSE26886 | DERA | 51071 | 218102_at | -0.1394 | 0.6267 | |
| GSE29001 | DERA | 51071 | 218102_at | 0.2628 | 0.4148 | |
| GSE38129 | DERA | 51071 | 218102_at | 0.1544 | 0.4273 | |
| GSE45670 | DERA | 51071 | 218102_at | 0.2124 | 0.1860 | |
| GSE53622 | DERA | 51071 | 34748 | 0.0781 | 0.4477 | |
| GSE53624 | DERA | 51071 | 34748 | 0.0527 | 0.4313 | |
| GSE63941 | DERA | 51071 | 218102_at | 0.6210 | 0.1965 | |
| GSE77861 | DERA | 51071 | 218102_at | 0.5159 | 0.1743 | |
| GSE97050 | DERA | 51071 | A_23_P25253 | 0.0857 | 0.7942 | |
| SRP007169 | DERA | 51071 | RNAseq | -0.3941 | 0.2782 | |
| SRP008496 | DERA | 51071 | RNAseq | -0.2526 | 0.2064 | |
| SRP064894 | DERA | 51071 | RNAseq | -0.3121 | 0.0238 | |
| SRP133303 | DERA | 51071 | RNAseq | 0.4976 | 0.0039 | |
| SRP159526 | DERA | 51071 | RNAseq | -0.1942 | 0.4130 | |
| SRP193095 | DERA | 51071 | RNAseq | -0.4751 | 0.0015 | |
| SRP219564 | DERA | 51071 | RNAseq | -0.2381 | 0.3417 | |
| TCGA | DERA | 51071 | RNAseq | 0.2224 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DERA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DERA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DERA | 51071 | 7 | 2 | 21 | |
| GSE20123 | DERA | 51071 | 7 | 2 | 21 | |
| GSE43470 | DERA | 51071 | 9 | 4 | 30 | |
| GSE46452 | DERA | 51071 | 10 | 1 | 48 | |
| GSE47630 | DERA | 51071 | 14 | 1 | 25 | |
| GSE54993 | DERA | 51071 | 1 | 9 | 60 | |
| GSE54994 | DERA | 51071 | 11 | 2 | 40 | |
| GSE60625 | DERA | 51071 | 0 | 1 | 10 | |
| GSE74703 | DERA | 51071 | 9 | 3 | 24 | |
| GSE74704 | DERA | 51071 | 5 | 1 | 14 | |
| TCGA | DERA | 51071 | 41 | 5 | 50 |
Total number of gains: 114; Total number of losses: 31; Total Number of normals: 343.
Somatic mutations of DERA:
Generating mutation plots.
Highly correlated genes for DERA:
Showing top 20/551 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DERA | TAS2R19 | 0.76889 | 3 | 0 | 3 |
| DERA | ATF6 | 0.758594 | 3 | 0 | 3 |
| DERA | MORC4 | 0.728322 | 4 | 0 | 3 |
| DERA | PANX1 | 0.714441 | 3 | 0 | 3 |
| DERA | COPS4 | 0.708751 | 3 | 0 | 3 |
| DERA | CDC42SE2 | 0.701012 | 3 | 0 | 3 |
| DERA | MRPL50 | 0.697888 | 3 | 0 | 3 |
| DERA | HYLS1 | 0.692551 | 4 | 0 | 3 |
| DERA | SLCO3A1 | 0.692109 | 4 | 0 | 3 |
| DERA | POLR3C | 0.691712 | 4 | 0 | 4 |
| DERA | SLC16A14 | 0.683549 | 3 | 0 | 3 |
| DERA | ARHGEF5 | 0.683288 | 4 | 0 | 3 |
| DERA | TAF7 | 0.681947 | 3 | 0 | 3 |
| DERA | PTPMT1 | 0.675899 | 5 | 0 | 4 |
| DERA | LIPT1 | 0.674632 | 3 | 0 | 3 |
| DERA | ZBED5-AS1 | 0.67173 | 3 | 0 | 3 |
| DERA | GPHN | 0.670829 | 5 | 0 | 4 |
| DERA | MRPS11 | 0.670468 | 4 | 0 | 3 |
| DERA | KLHL13 | 0.667856 | 4 | 0 | 4 |
| DERA | SESN3 | 0.663109 | 4 | 0 | 3 |
For details and further investigation, click here
