| Full name: DiGeorge syndrome critical region gene 9 | Alias Symbol: DGS-A|POM121L5P | ||
| Type: non-coding RNA | Cytoband: 22q11.21 | ||
| Entrez ID: 25787 | HGNC ID: HGNC:17227 | Ensembl Gene: ENSG00000273032 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DGCR9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGCR9 | 25787 | 215003_at | 0.0096 | 0.9761 | |
| GSE20347 | DGCR9 | 25787 | 215003_at | -0.0529 | 0.4727 | |
| GSE23400 | DGCR9 | 25787 | 215003_at | -0.1208 | 0.0008 | |
| GSE26886 | DGCR9 | 25787 | 215003_at | 0.1196 | 0.2410 | |
| GSE29001 | DGCR9 | 25787 | 215003_at | -0.1539 | 0.4001 | |
| GSE38129 | DGCR9 | 25787 | 215003_at | -0.0528 | 0.5403 | |
| GSE45670 | DGCR9 | 25787 | 215003_at | 0.0457 | 0.7467 | |
| GSE53622 | DGCR9 | 25787 | 78300 | 0.2193 | 0.1622 | |
| GSE53624 | DGCR9 | 25787 | 78300 | 0.4992 | 0.0000 | |
| GSE63941 | DGCR9 | 25787 | 215003_at | 0.1668 | 0.2871 | |
| GSE77861 | DGCR9 | 25787 | 215003_at | 0.0903 | 0.4903 | |
| SRP219564 | DGCR9 | 25787 | RNAseq | 0.8660 | 0.1175 | |
| TCGA | DGCR9 | 25787 | RNAseq | 1.4654 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DGCR9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGCR9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGCR9 | 25787 | 4 | 8 | 18 | |
| GSE20123 | DGCR9 | 25787 | 4 | 8 | 18 | |
| GSE43470 | DGCR9 | 25787 | 5 | 7 | 31 | |
| GSE46452 | DGCR9 | 25787 | 32 | 2 | 25 | |
| GSE47630 | DGCR9 | 25787 | 8 | 5 | 27 | |
| GSE54993 | DGCR9 | 25787 | 3 | 6 | 61 | |
| GSE54994 | DGCR9 | 25787 | 12 | 7 | 34 | |
| GSE60625 | DGCR9 | 25787 | 5 | 0 | 6 | |
| GSE74703 | DGCR9 | 25787 | 5 | 5 | 26 | |
| GSE74704 | DGCR9 | 25787 | 2 | 5 | 13 |
Total number of gains: 80; Total number of losses: 53; Total Number of normals: 259.
Somatic mutations of DGCR9:
Generating mutation plots.
Highly correlated genes for DGCR9:
Showing top 20/437 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGCR9 | TAOK2 | 0.746758 | 3 | 0 | 3 |
| DGCR9 | CYP2A13 | 0.717698 | 3 | 0 | 3 |
| DGCR9 | C11orf72 | 0.675526 | 3 | 0 | 3 |
| DGCR9 | MTHFR | 0.667898 | 3 | 0 | 3 |
| DGCR9 | RFPL3 | 0.662188 | 3 | 0 | 3 |
| DGCR9 | POU3F4 | 0.661806 | 3 | 0 | 3 |
| DGCR9 | PNOC | 0.660814 | 3 | 0 | 3 |
| DGCR9 | PTPRO | 0.65584 | 3 | 0 | 3 |
| DGCR9 | GRIK5 | 0.655698 | 5 | 0 | 4 |
| DGCR9 | CTLA4 | 0.652048 | 3 | 0 | 3 |
| DGCR9 | MINK1 | 0.651765 | 3 | 0 | 3 |
| DGCR9 | NANOG | 0.650567 | 3 | 0 | 3 |
| DGCR9 | TNFRSF4 | 0.644773 | 3 | 0 | 3 |
| DGCR9 | KIR2DS2 | 0.644695 | 4 | 0 | 3 |
| DGCR9 | LGR5 | 0.643097 | 3 | 0 | 3 |
| DGCR9 | PLA2G2E | 0.6412 | 4 | 0 | 4 |
| DGCR9 | ECE2 | 0.637878 | 4 | 0 | 3 |
| DGCR9 | DMWD | 0.637735 | 3 | 0 | 3 |
| DGCR9 | IFNA14 | 0.635569 | 5 | 0 | 3 |
| DGCR9 | MMP8 | 0.63478 | 3 | 0 | 3 |
For details and further investigation, click here
