| Full name: DnaJ heat shock protein family (Hsp40) member B1 | Alias Symbol: Hsp40|Sis1|RSPH16B | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 3337 | HGNC ID: HGNC:5270 | Ensembl Gene: ENSG00000132002 | OMIM ID: 604572 |
| Drug and gene relationship at DGIdb | |||
DNAJB1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05164 | Influenza A |
Expression of DNAJB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB1 | 3337 | 200666_s_at | -0.9870 | 0.0842 | |
| GSE20347 | DNAJB1 | 3337 | 200666_s_at | -0.6020 | 0.0000 | |
| GSE23400 | DNAJB1 | 3337 | 200666_s_at | -0.5496 | 0.0000 | |
| GSE26886 | DNAJB1 | 3337 | 200666_s_at | -1.6416 | 0.0000 | |
| GSE29001 | DNAJB1 | 3337 | 200666_s_at | -0.6660 | 0.0384 | |
| GSE38129 | DNAJB1 | 3337 | 200666_s_at | -0.3506 | 0.1170 | |
| GSE45670 | DNAJB1 | 3337 | 200666_s_at | 0.0094 | 0.9795 | |
| GSE53622 | DNAJB1 | 3337 | 28 | -0.9734 | 0.0000 | |
| GSE53624 | DNAJB1 | 3337 | 28 | -0.8397 | 0.0000 | |
| GSE63941 | DNAJB1 | 3337 | 200666_s_at | 1.4279 | 0.0012 | |
| GSE77861 | DNAJB1 | 3337 | 200666_s_at | -0.4056 | 0.0651 | |
| GSE97050 | DNAJB1 | 3337 | A_23_P90062 | -0.8553 | 0.0672 | |
| SRP007169 | DNAJB1 | 3337 | RNAseq | -2.1808 | 0.0000 | |
| SRP008496 | DNAJB1 | 3337 | RNAseq | -2.0554 | 0.0000 | |
| SRP064894 | DNAJB1 | 3337 | RNAseq | -1.1584 | 0.0002 | |
| SRP133303 | DNAJB1 | 3337 | RNAseq | -0.7736 | 0.0002 | |
| SRP159526 | DNAJB1 | 3337 | RNAseq | -1.2616 | 0.0000 | |
| SRP193095 | DNAJB1 | 3337 | RNAseq | -0.9452 | 0.0001 | |
| SRP219564 | DNAJB1 | 3337 | RNAseq | -1.1405 | 0.1014 | |
| TCGA | DNAJB1 | 3337 | RNAseq | 0.0849 | 0.2052 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by DNAJB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB1 | 3337 | 4 | 2 | 24 | |
| GSE20123 | DNAJB1 | 3337 | 3 | 1 | 26 | |
| GSE43470 | DNAJB1 | 3337 | 2 | 6 | 35 | |
| GSE46452 | DNAJB1 | 3337 | 47 | 1 | 11 | |
| GSE47630 | DNAJB1 | 3337 | 4 | 7 | 29 | |
| GSE54993 | DNAJB1 | 3337 | 15 | 4 | 51 | |
| GSE54994 | DNAJB1 | 3337 | 6 | 13 | 34 | |
| GSE60625 | DNAJB1 | 3337 | 9 | 0 | 2 | |
| GSE74703 | DNAJB1 | 3337 | 2 | 4 | 30 | |
| GSE74704 | DNAJB1 | 3337 | 0 | 1 | 19 | |
| TCGA | DNAJB1 | 3337 | 18 | 11 | 67 |
Total number of gains: 110; Total number of losses: 50; Total Number of normals: 328.
Somatic mutations of DNAJB1:
Generating mutation plots.
Highly correlated genes for DNAJB1:
Showing top 20/947 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB1 | NFYC | 0.787019 | 3 | 0 | 3 |
| DNAJB1 | SNORA68 | 0.777568 | 3 | 0 | 3 |
| DNAJB1 | S100A16 | 0.745245 | 4 | 0 | 4 |
| DNAJB1 | CAPN14 | 0.721518 | 4 | 0 | 4 |
| DNAJB1 | VSIG10L | 0.715669 | 5 | 0 | 5 |
| DNAJB1 | MPZL3 | 0.714067 | 6 | 0 | 6 |
| DNAJB1 | FCHO2 | 0.701284 | 6 | 0 | 6 |
| DNAJB1 | APOBEC1 | 0.700425 | 4 | 0 | 4 |
| DNAJB1 | CYSRT1 | 0.69213 | 5 | 0 | 5 |
| DNAJB1 | WNK2 | 0.691054 | 3 | 0 | 3 |
| DNAJB1 | SCYL2 | 0.689688 | 4 | 0 | 4 |
| DNAJB1 | FAM135A | 0.689579 | 5 | 0 | 5 |
| DNAJB1 | MYL3 | 0.683881 | 3 | 0 | 3 |
| DNAJB1 | PRPF38A | 0.681984 | 4 | 0 | 3 |
| DNAJB1 | HS3ST6 | 0.681063 | 4 | 0 | 3 |
| DNAJB1 | PDCD6IP | 0.680393 | 9 | 0 | 9 |
| DNAJB1 | SMDT1 | 0.680277 | 3 | 0 | 3 |
| DNAJB1 | UBE2D2 | 0.677342 | 5 | 0 | 4 |
| DNAJB1 | RAET1E | 0.67702 | 5 | 0 | 5 |
| DNAJB1 | DEGS2 | 0.675407 | 5 | 0 | 4 |
For details and further investigation, click here
