| Full name: family with sequence similarity 135 member A | Alias Symbol: FLJ20176 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 57579 | HGNC ID: HGNC:21084 | Ensembl Gene: ENSG00000082269 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM135A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM135A | 57579 | 223497_at | -1.0167 | 0.2727 | |
| GSE20347 | FAM135A | 57579 | 221233_s_at | -0.0880 | 0.1099 | |
| GSE23400 | FAM135A | 57579 | 221233_s_at | -0.0523 | 0.0114 | |
| GSE26886 | FAM135A | 57579 | 223497_at | -2.3813 | 0.0000 | |
| GSE29001 | FAM135A | 57579 | 221233_s_at | -0.1299 | 0.4568 | |
| GSE38129 | FAM135A | 57579 | 221233_s_at | -0.1476 | 0.0523 | |
| GSE45670 | FAM135A | 57579 | 223497_at | -0.3991 | 0.1613 | |
| GSE53622 | FAM135A | 57579 | 114202 | -1.2549 | 0.0000 | |
| GSE53624 | FAM135A | 57579 | 114202 | -1.4284 | 0.0000 | |
| GSE63941 | FAM135A | 57579 | 223497_at | -0.0483 | 0.9434 | |
| GSE77861 | FAM135A | 57579 | 223497_at | -0.7711 | 0.2929 | |
| GSE97050 | FAM135A | 57579 | A_23_P58862 | -0.2583 | 0.4794 | |
| SRP007169 | FAM135A | 57579 | RNAseq | -1.2168 | 0.0010 | |
| SRP008496 | FAM135A | 57579 | RNAseq | -1.6144 | 0.0000 | |
| SRP064894 | FAM135A | 57579 | RNAseq | -1.8659 | 0.0000 | |
| SRP133303 | FAM135A | 57579 | RNAseq | -1.0433 | 0.0000 | |
| SRP159526 | FAM135A | 57579 | RNAseq | -1.7426 | 0.0003 | |
| SRP193095 | FAM135A | 57579 | RNAseq | -1.6248 | 0.0000 | |
| SRP219564 | FAM135A | 57579 | RNAseq | -1.8432 | 0.0055 | |
| TCGA | FAM135A | 57579 | RNAseq | 0.0023 | 0.9809 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by FAM135A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM135A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM135A | 57579 | 2 | 2 | 26 | |
| GSE20123 | FAM135A | 57579 | 2 | 1 | 27 | |
| GSE43470 | FAM135A | 57579 | 3 | 0 | 40 | |
| GSE46452 | FAM135A | 57579 | 2 | 11 | 46 | |
| GSE47630 | FAM135A | 57579 | 8 | 4 | 28 | |
| GSE54993 | FAM135A | 57579 | 3 | 2 | 65 | |
| GSE54994 | FAM135A | 57579 | 9 | 5 | 39 | |
| GSE60625 | FAM135A | 57579 | 0 | 2 | 9 | |
| GSE74703 | FAM135A | 57579 | 3 | 0 | 33 | |
| GSE74704 | FAM135A | 57579 | 0 | 1 | 19 | |
| TCGA | FAM135A | 57579 | 11 | 19 | 66 |
Total number of gains: 43; Total number of losses: 47; Total Number of normals: 398.
Somatic mutations of FAM135A:
Generating mutation plots.
Highly correlated genes for FAM135A:
Showing top 20/1288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM135A | PRSS27 | 0.824963 | 6 | 0 | 6 |
| FAM135A | SPINK7 | 0.823118 | 6 | 0 | 6 |
| FAM135A | CAPN14 | 0.822543 | 6 | 0 | 6 |
| FAM135A | CYSRT1 | 0.816019 | 6 | 0 | 6 |
| FAM135A | SERPINB1 | 0.805422 | 7 | 0 | 7 |
| FAM135A | CTNND1 | 0.803424 | 3 | 0 | 3 |
| FAM135A | FAM3D | 0.795804 | 7 | 0 | 7 |
| FAM135A | TMPRSS11B | 0.789944 | 7 | 0 | 7 |
| FAM135A | SMIM5 | 0.788613 | 6 | 0 | 6 |
| FAM135A | CSTB | 0.78601 | 7 | 0 | 7 |
| FAM135A | FAM3B | 0.772059 | 6 | 0 | 6 |
| FAM135A | C15orf62 | 0.770584 | 7 | 0 | 7 |
| FAM135A | EP300-AS1 | 0.768647 | 3 | 0 | 3 |
| FAM135A | NIPAL1 | 0.767708 | 3 | 0 | 3 |
| FAM135A | ARHGAP27 | 0.7613 | 8 | 0 | 7 |
| FAM135A | RAET1E | 0.760157 | 6 | 0 | 6 |
| FAM135A | TMEM45B | 0.75827 | 8 | 0 | 7 |
| FAM135A | MUC15 | 0.754653 | 7 | 0 | 6 |
| FAM135A | CAPNS2 | 0.752644 | 5 | 0 | 5 |
| FAM135A | CD24 | 0.751822 | 7 | 0 | 7 |
For details and further investigation, click here
