RPN2

 

Full name: ribophorin II Alias Symbol: SWP1|RPNII|RIBIIR|RPN-II
Type: protein-coding gene Cytoband: 20q11.23
Entrez ID: 6185 HGNC ID: HGNC:10382 Ensembl Gene: ENSG00000118705 OMIM ID: 180490
Drug and gene relationship at DGIdb

 

Expression of RPN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RPN2 6185 213399_x_at 0.9538 0.0365
GSE20347 RPN2 6185 213399_x_at 0.6777 0.0000
GSE23400 RPN2 6185 213491_x_at 0.6728 0.0000
GSE26886 RPN2 6185 213399_x_at 0.7062 0.0007
GSE29001 RPN2 6185 213491_x_at 0.6843 0.0049
GSE38129 RPN2 6185 213399_x_at 0.7943 0.0000
GSE45670 RPN2 6185 213399_x_at 0.5595 0.0000
GSE53622 RPN2 6185 10393 0.7814 0.0000
GSE53624 RPN2 6185 123071 0.9146 0.0000
GSE63941 RPN2 6185 213399_x_at -0.1376 0.8043
GSE77861 RPN2 6185 213399_x_at 0.4397 0.0186
GSE97050 RPN2 6185 A_33_P3332145 1.0510 0.0706
SRP007169 RPN2 6185 RNAseq 0.0617 0.8579
SRP008496 RPN2 6185 RNAseq 0.2006 0.4334
SRP064894 RPN2 6185 RNAseq 0.8882 0.0000
SRP133303 RPN2 6185 RNAseq 0.7681 0.0000
SRP159526 RPN2 6185 RNAseq 0.8761 0.0000
SRP193095 RPN2 6185 RNAseq 0.3206 0.0270
SRP219564 RPN2 6185 RNAseq 0.9433 0.0161
TCGA RPN2 6185 RNAseq 0.0625 0.1165

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RPN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPN2 6185 14 2 14
GSE20123 RPN2 6185 14 2 14
GSE43470 RPN2 6185 13 0 30
GSE46452 RPN2 6185 29 0 30
GSE47630 RPN2 6185 24 0 16
GSE54993 RPN2 6185 0 17 53
GSE54994 RPN2 6185 24 0 29
GSE60625 RPN2 6185 0 0 11
GSE74703 RPN2 6185 11 0 25
GSE74704 RPN2 6185 10 1 9
TCGA RPN2 6185 47 3 46

Total number of gains: 186; Total number of losses: 25; Total Number of normals: 277.  

 

Somatic mutations of RPN2:

 

Generating mutation plots.

 

Highly correlated genes for RPN2:

 

Showing top 20/1953 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPN2UBE2C0.76442711011
RPN2AURKA0.76176711011
RPN2MCM80.754245707
RPN2APMAP0.7483151009
RPN2GINS10.74784411011
RPN2PCNA0.74716111011
RPN2EFTUD20.745987707
RPN2TPX20.73422211010
RPN2ENTPD60.732064606
RPN2B3GALT60.731786606
RPN2CCT50.7316707
RPN2TMEM132A0.730584808
RPN2CDCA20.724746505
RPN2DNMT10.72463411011
RPN2DSN10.723991009
RPN2FAM91A10.723643606
RPN2MYBL20.72231611011
RPN2PDIA50.72125303
RPN2SLC19A10.720449303
RPN2DZANK10.719521303

For details and further investigation, click here