| Full name: enoyl-CoA delta isomerase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 1632 | HGNC ID: HGNC:2703 | Ensembl Gene: ENSG00000167969 | OMIM ID: 600305 |
| Drug and gene relationship at DGIdb | |||
Expression of ECI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECI1 | 1632 | 209759_s_at | -0.1387 | 0.8516 | |
| GSE20347 | ECI1 | 1632 | 209759_s_at | 0.2121 | 0.1386 | |
| GSE23400 | ECI1 | 1632 | 209759_s_at | 0.0546 | 0.5054 | |
| GSE26886 | ECI1 | 1632 | 209759_s_at | 0.1925 | 0.3344 | |
| GSE29001 | ECI1 | 1632 | 209759_s_at | -0.0195 | 0.9686 | |
| GSE38129 | ECI1 | 1632 | 209759_s_at | 0.1002 | 0.4539 | |
| GSE45670 | ECI1 | 1632 | 209759_s_at | -0.0176 | 0.9290 | |
| GSE53622 | ECI1 | 1632 | 114346 | -0.1272 | 0.0898 | |
| GSE53624 | ECI1 | 1632 | 114346 | 0.1123 | 0.0601 | |
| GSE63941 | ECI1 | 1632 | 209759_s_at | 1.5324 | 0.0014 | |
| GSE77861 | ECI1 | 1632 | 209759_s_at | 0.2879 | 0.1638 | |
| GSE97050 | ECI1 | 1632 | A_23_P163647 | -0.2856 | 0.3023 | |
| SRP007169 | ECI1 | 1632 | RNAseq | 0.0477 | 0.9163 | |
| SRP008496 | ECI1 | 1632 | RNAseq | -0.0480 | 0.8717 | |
| SRP064894 | ECI1 | 1632 | RNAseq | -0.0715 | 0.8358 | |
| SRP133303 | ECI1 | 1632 | RNAseq | 0.2743 | 0.2792 | |
| SRP159526 | ECI1 | 1632 | RNAseq | 0.3122 | 0.3234 | |
| SRP193095 | ECI1 | 1632 | RNAseq | -0.0405 | 0.7856 | |
| SRP219564 | ECI1 | 1632 | RNAseq | 0.1066 | 0.7729 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ECI1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ECI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECI1 | 1632 | 5 | 5 | 20 | |
| GSE20123 | ECI1 | 1632 | 5 | 4 | 21 | |
| GSE43470 | ECI1 | 1632 | 4 | 7 | 32 | |
| GSE46452 | ECI1 | 1632 | 38 | 1 | 20 | |
| GSE47630 | ECI1 | 1632 | 13 | 6 | 21 | |
| GSE54993 | ECI1 | 1632 | 3 | 5 | 62 | |
| GSE54994 | ECI1 | 1632 | 5 | 9 | 39 | |
| GSE60625 | ECI1 | 1632 | 4 | 0 | 7 | |
| GSE74703 | ECI1 | 1632 | 4 | 5 | 27 | |
| GSE74704 | ECI1 | 1632 | 3 | 2 | 15 | |
| TCGA | ECI1 | 1632 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of ECI1:
Generating mutation plots.
Highly correlated genes for ECI1:
Showing top 20/169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECI1 | NDUFB10 | 0.734108 | 5 | 0 | 5 |
| ECI1 | SOX2 | 0.696267 | 4 | 0 | 4 |
| ECI1 | NEDD4L | 0.693454 | 5 | 0 | 5 |
| ECI1 | PTPRZ1 | 0.679518 | 3 | 0 | 3 |
| ECI1 | TBL1X | 0.669913 | 3 | 0 | 3 |
| ECI1 | NSMCE1 | 0.657601 | 4 | 0 | 3 |
| ECI1 | ATL2 | 0.651696 | 3 | 0 | 3 |
| ECI1 | TACC2 | 0.642884 | 3 | 0 | 3 |
| ECI1 | MRPL10 | 0.642157 | 4 | 0 | 4 |
| ECI1 | MTUS1 | 0.638257 | 4 | 0 | 4 |
| ECI1 | GTF2I | 0.636824 | 4 | 0 | 3 |
| ECI1 | BNIP2 | 0.63495 | 3 | 0 | 3 |
| ECI1 | RSL24D1 | 0.632804 | 4 | 0 | 3 |
| ECI1 | PARN | 0.63177 | 5 | 0 | 4 |
| ECI1 | COL28A1 | 0.629657 | 3 | 0 | 3 |
| ECI1 | MRPL38 | 0.628138 | 3 | 0 | 3 |
| ECI1 | KIF5C | 0.622256 | 3 | 0 | 3 |
| ECI1 | ARPP19 | 0.621418 | 4 | 0 | 3 |
| ECI1 | CNTN1 | 0.619866 | 4 | 0 | 3 |
| ECI1 | NELFCD | 0.609434 | 3 | 0 | 3 |
For details and further investigation, click here
