| Full name: myelin protein zero like 2 | Alias Symbol: EVA | ||
| Type: protein-coding gene | Cytoband: 11q24 | ||
| Entrez ID: 10205 | HGNC ID: HGNC:3496 | Ensembl Gene: ENSG00000149573 | OMIM ID: 604873 |
| Drug and gene relationship at DGIdb | |||
Expression of MPZL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPZL2 | 10205 | 203780_at | -0.7588 | 0.3296 | |
| GSE20347 | MPZL2 | 10205 | 203780_at | -1.7919 | 0.0000 | |
| GSE23400 | MPZL2 | 10205 | 203780_at | -1.2638 | 0.0000 | |
| GSE26886 | MPZL2 | 10205 | 203780_at | -2.0550 | 0.0000 | |
| GSE29001 | MPZL2 | 10205 | 203780_at | -1.3777 | 0.0057 | |
| GSE38129 | MPZL2 | 10205 | 203780_at | -1.0500 | 0.0622 | |
| GSE45670 | MPZL2 | 10205 | 203780_at | -0.1066 | 0.7607 | |
| GSE53622 | MPZL2 | 10205 | 127473 | -1.1248 | 0.0000 | |
| GSE53624 | MPZL2 | 10205 | 127473 | -1.6309 | 0.0000 | |
| GSE63941 | MPZL2 | 10205 | 203780_at | 4.2380 | 0.0007 | |
| GSE77861 | MPZL2 | 10205 | 203780_at | -1.0767 | 0.0053 | |
| GSE97050 | MPZL2 | 10205 | A_33_P3215948 | -0.0327 | 0.9792 | |
| SRP007169 | MPZL2 | 10205 | RNAseq | -2.8935 | 0.0000 | |
| SRP008496 | MPZL2 | 10205 | RNAseq | -2.5732 | 0.0000 | |
| SRP064894 | MPZL2 | 10205 | RNAseq | -1.7502 | 0.0000 | |
| SRP133303 | MPZL2 | 10205 | RNAseq | -1.7937 | 0.0000 | |
| SRP159526 | MPZL2 | 10205 | RNAseq | -2.3283 | 0.0001 | |
| SRP193095 | MPZL2 | 10205 | RNAseq | -1.9771 | 0.0000 | |
| SRP219564 | MPZL2 | 10205 | RNAseq | -2.3420 | 0.0055 | |
| TCGA | MPZL2 | 10205 | RNAseq | 0.1523 | 0.1462 |
Upregulated datasets: 1; Downregulated datasets: 14.
Survival by MPZL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPZL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPZL2 | 10205 | 2 | 11 | 17 | |
| GSE20123 | MPZL2 | 10205 | 2 | 11 | 17 | |
| GSE43470 | MPZL2 | 10205 | 2 | 9 | 32 | |
| GSE46452 | MPZL2 | 10205 | 3 | 26 | 30 | |
| GSE47630 | MPZL2 | 10205 | 2 | 19 | 19 | |
| GSE54993 | MPZL2 | 10205 | 10 | 0 | 60 | |
| GSE54994 | MPZL2 | 10205 | 6 | 19 | 28 | |
| GSE60625 | MPZL2 | 10205 | 0 | 3 | 8 | |
| GSE74703 | MPZL2 | 10205 | 1 | 6 | 29 | |
| GSE74704 | MPZL2 | 10205 | 1 | 7 | 12 | |
| TCGA | MPZL2 | 10205 | 6 | 49 | 41 |
Total number of gains: 35; Total number of losses: 160; Total Number of normals: 293.
Somatic mutations of MPZL2:
Generating mutation plots.
Highly correlated genes for MPZL2:
Showing top 20/1411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPZL2 | NIPAL1 | 0.822461 | 3 | 0 | 3 |
| MPZL2 | CERS3 | 0.816711 | 7 | 0 | 7 |
| MPZL2 | SERPINB1 | 0.812468 | 12 | 0 | 11 |
| MPZL2 | ARHGAP32 | 0.807045 | 11 | 0 | 11 |
| MPZL2 | TGM1 | 0.804973 | 12 | 0 | 12 |
| MPZL2 | EPGN | 0.804891 | 3 | 0 | 3 |
| MPZL2 | ARHGAP27 | 0.793832 | 8 | 0 | 8 |
| MPZL2 | CTNND1 | 0.791248 | 3 | 0 | 3 |
| MPZL2 | TMEM40 | 0.787995 | 13 | 0 | 12 |
| MPZL2 | DSG3 | 0.786546 | 13 | 0 | 12 |
| MPZL2 | EHF | 0.783028 | 13 | 0 | 12 |
| MPZL2 | ZNF185 | 0.782646 | 13 | 0 | 13 |
| MPZL2 | RBM47 | 0.780406 | 12 | 0 | 12 |
| MPZL2 | RASSF5 | 0.780047 | 7 | 0 | 7 |
| MPZL2 | JUP | 0.77808 | 9 | 0 | 9 |
| MPZL2 | VPS4B | 0.775374 | 11 | 0 | 11 |
| MPZL2 | CKMT1A | 0.774132 | 3 | 0 | 3 |
| MPZL2 | RAB25 | 0.773831 | 12 | 0 | 12 |
| MPZL2 | SPAG17 | 0.77215 | 5 | 0 | 5 |
| MPZL2 | C1orf116 | 0.771905 | 13 | 0 | 13 |
For details and further investigation, click here
