| Full name: E74 like ETS transcription factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 1997 | HGNC ID: HGNC:3316 | Ensembl Gene: ENSG00000120690 | OMIM ID: 189973 |
| Drug and gene relationship at DGIdb | |||
Expression of ELF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELF1 | 1997 | 212418_at | -0.2288 | 0.2757 | |
| GSE20347 | ELF1 | 1997 | 212420_at | -0.7798 | 0.0000 | |
| GSE23400 | ELF1 | 1997 | 212420_at | -0.1900 | 0.0065 | |
| GSE26886 | ELF1 | 1997 | 212420_at | -1.5562 | 0.0002 | |
| GSE29001 | ELF1 | 1997 | 212420_at | -0.6433 | 0.0379 | |
| GSE38129 | ELF1 | 1997 | 212420_at | -0.4827 | 0.0004 | |
| GSE45670 | ELF1 | 1997 | 212418_at | -0.2822 | 0.1156 | |
| GSE53622 | ELF1 | 1997 | 136896 | -0.4888 | 0.0000 | |
| GSE53624 | ELF1 | 1997 | 136896 | -0.5178 | 0.0000 | |
| GSE63941 | ELF1 | 1997 | 212418_at | -0.8041 | 0.0695 | |
| GSE77861 | ELF1 | 1997 | 212418_at | -0.0775 | 0.8172 | |
| GSE97050 | ELF1 | 1997 | A_33_P3278068 | 0.1824 | 0.5574 | |
| SRP007169 | ELF1 | 1997 | RNAseq | -1.2938 | 0.0002 | |
| SRP008496 | ELF1 | 1997 | RNAseq | -1.1048 | 0.0000 | |
| SRP064894 | ELF1 | 1997 | RNAseq | -0.6989 | 0.0161 | |
| SRP133303 | ELF1 | 1997 | RNAseq | -0.5342 | 0.0001 | |
| SRP159526 | ELF1 | 1997 | RNAseq | -0.9540 | 0.1041 | |
| SRP193095 | ELF1 | 1997 | RNAseq | -0.6616 | 0.0000 | |
| SRP219564 | ELF1 | 1997 | RNAseq | -0.5775 | 0.1587 | |
| TCGA | ELF1 | 1997 | RNAseq | -0.0333 | 0.5050 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ELF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELF1 | 1997 | 0 | 15 | 15 | |
| GSE20123 | ELF1 | 1997 | 0 | 14 | 16 | |
| GSE43470 | ELF1 | 1997 | 3 | 13 | 27 | |
| GSE46452 | ELF1 | 1997 | 0 | 33 | 26 | |
| GSE47630 | ELF1 | 1997 | 2 | 27 | 11 | |
| GSE54993 | ELF1 | 1997 | 12 | 2 | 56 | |
| GSE54994 | ELF1 | 1997 | 1 | 16 | 36 | |
| GSE60625 | ELF1 | 1997 | 0 | 3 | 8 | |
| GSE74703 | ELF1 | 1997 | 3 | 10 | 23 | |
| GSE74704 | ELF1 | 1997 | 0 | 11 | 9 | |
| TCGA | ELF1 | 1997 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 184; Total Number of normals: 276.
Somatic mutations of ELF1:
Generating mutation plots.
Highly correlated genes for ELF1:
Showing top 20/938 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELF1 | PSMD8 | 0.766753 | 3 | 0 | 3 |
| ELF1 | EIF3I | 0.725276 | 3 | 0 | 3 |
| ELF1 | TMEM50A | 0.704374 | 3 | 0 | 3 |
| ELF1 | FAM83G | 0.703956 | 3 | 0 | 3 |
| ELF1 | EPG5 | 0.695313 | 4 | 0 | 4 |
| ELF1 | MAB21L3 | 0.692837 | 4 | 0 | 4 |
| ELF1 | SLC44A3 | 0.688809 | 5 | 0 | 5 |
| ELF1 | NAGK | 0.687622 | 9 | 0 | 7 |
| ELF1 | DGKA | 0.680375 | 8 | 0 | 8 |
| ELF1 | ARPC1A | 0.679767 | 4 | 0 | 4 |
| ELF1 | ATP6V1C2 | 0.679661 | 3 | 0 | 3 |
| ELF1 | ZNF416 | 0.671436 | 3 | 0 | 3 |
| ELF1 | SLC44A2 | 0.669697 | 5 | 0 | 4 |
| ELF1 | WNK1 | 0.668381 | 7 | 0 | 6 |
| ELF1 | GBP6 | 0.667203 | 3 | 0 | 3 |
| ELF1 | HTATIP2 | 0.6656 | 3 | 0 | 3 |
| ELF1 | TRAF3IP2 | 0.662586 | 3 | 0 | 3 |
| ELF1 | WDR77 | 0.659916 | 3 | 0 | 3 |
| ELF1 | FAM3D | 0.658187 | 4 | 0 | 4 |
| ELF1 | CERS3 | 0.657793 | 4 | 0 | 4 |
For details and further investigation, click here
