| Full name: TRAF3 interacting protein 2 | Alias Symbol: DKFZP586G0522|ACT1|CIKS | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 10758 | HGNC ID: HGNC:1343 | Ensembl Gene: ENSG00000056972 | OMIM ID: 607043 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAF3IP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAF3IP2 | 10758 | 215411_s_at | -0.1825 | 0.7963 | |
| GSE20347 | TRAF3IP2 | 10758 | 215411_s_at | -0.1686 | 0.2129 | |
| GSE23400 | TRAF3IP2 | 10758 | 215411_s_at | 0.0930 | 0.2677 | |
| GSE26886 | TRAF3IP2 | 10758 | 215411_s_at | -0.0975 | 0.5874 | |
| GSE29001 | TRAF3IP2 | 10758 | 215411_s_at | -0.2188 | 0.1834 | |
| GSE38129 | TRAF3IP2 | 10758 | 215411_s_at | 0.0514 | 0.7532 | |
| GSE45670 | TRAF3IP2 | 10758 | 215411_s_at | 0.1212 | 0.4136 | |
| GSE53622 | TRAF3IP2 | 10758 | 621 | 0.0705 | 0.3843 | |
| GSE53624 | TRAF3IP2 | 10758 | 621 | -0.0114 | 0.8765 | |
| GSE63941 | TRAF3IP2 | 10758 | 215411_s_at | 0.2328 | 0.7475 | |
| GSE77861 | TRAF3IP2 | 10758 | 215411_s_at | 0.2008 | 0.2923 | |
| GSE97050 | TRAF3IP2 | 10758 | A_33_P3343428 | 0.2141 | 0.5912 | |
| SRP007169 | TRAF3IP2 | 10758 | RNAseq | -1.0983 | 0.0006 | |
| SRP008496 | TRAF3IP2 | 10758 | RNAseq | -0.9080 | 0.0000 | |
| SRP064894 | TRAF3IP2 | 10758 | RNAseq | -0.3038 | 0.0779 | |
| SRP133303 | TRAF3IP2 | 10758 | RNAseq | -0.1058 | 0.5369 | |
| SRP159526 | TRAF3IP2 | 10758 | RNAseq | -0.3660 | 0.0783 | |
| SRP193095 | TRAF3IP2 | 10758 | RNAseq | -0.0322 | 0.7881 | |
| SRP219564 | TRAF3IP2 | 10758 | RNAseq | -0.2905 | 0.4741 | |
| TCGA | TRAF3IP2 | 10758 | RNAseq | 0.0108 | 0.8590 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRAF3IP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAF3IP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAF3IP2 | 10758 | 2 | 4 | 24 | |
| GSE20123 | TRAF3IP2 | 10758 | 2 | 3 | 25 | |
| GSE43470 | TRAF3IP2 | 10758 | 3 | 1 | 39 | |
| GSE46452 | TRAF3IP2 | 10758 | 2 | 11 | 46 | |
| GSE47630 | TRAF3IP2 | 10758 | 9 | 4 | 27 | |
| GSE54993 | TRAF3IP2 | 10758 | 3 | 2 | 65 | |
| GSE54994 | TRAF3IP2 | 10758 | 8 | 8 | 37 | |
| GSE60625 | TRAF3IP2 | 10758 | 0 | 2 | 9 | |
| GSE74703 | TRAF3IP2 | 10758 | 2 | 1 | 33 | |
| GSE74704 | TRAF3IP2 | 10758 | 0 | 1 | 19 | |
| TCGA | TRAF3IP2 | 10758 | 7 | 23 | 66 |
Total number of gains: 38; Total number of losses: 60; Total Number of normals: 390.
Somatic mutations of TRAF3IP2:
Generating mutation plots.
Highly correlated genes for TRAF3IP2:
Showing top 20/121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAF3IP2 | PLA2G4A | 0.7099 | 3 | 0 | 3 |
| TRAF3IP2 | CD109 | 0.695938 | 3 | 0 | 3 |
| TRAF3IP2 | TNFAIP2 | 0.690675 | 4 | 0 | 4 |
| TRAF3IP2 | KLC3 | 0.690559 | 3 | 0 | 3 |
| TRAF3IP2 | ELF1 | 0.662586 | 3 | 0 | 3 |
| TRAF3IP2 | XRCC4 | 0.646363 | 3 | 0 | 3 |
| TRAF3IP2 | WDR20 | 0.64371 | 3 | 0 | 3 |
| TRAF3IP2 | SHC1 | 0.636225 | 3 | 0 | 3 |
| TRAF3IP2 | TMEM117 | 0.62737 | 3 | 0 | 3 |
| TRAF3IP2 | AP3B1 | 0.626885 | 5 | 0 | 3 |
| TRAF3IP2 | SERINC2 | 0.623256 | 5 | 0 | 5 |
| TRAF3IP2 | SERINC5 | 0.612506 | 3 | 0 | 3 |
| TRAF3IP2 | AHNAK2 | 0.609592 | 4 | 0 | 3 |
| TRAF3IP2 | DMKN | 0.608361 | 4 | 0 | 3 |
| TRAF3IP2 | PSMC5 | 0.60272 | 4 | 0 | 4 |
| TRAF3IP2 | SEMA4B | 0.602542 | 5 | 0 | 3 |
| TRAF3IP2 | MCTS1 | 0.602096 | 4 | 0 | 3 |
| TRAF3IP2 | MLKL | 0.599525 | 3 | 0 | 3 |
| TRAF3IP2 | TMEM107 | 0.59592 | 6 | 0 | 4 |
| TRAF3IP2 | NAGS | 0.592878 | 5 | 0 | 3 |
For details and further investigation, click here
