| Full name: epiphycan | Alias Symbol: Pg-Lb|SLRR3B | ||
| Type: protein-coding gene | Cytoband: 12q21.33 | ||
| Entrez ID: 1833 | HGNC ID: HGNC:3053 | Ensembl Gene: ENSG00000083782 | OMIM ID: 601657 |
| Drug and gene relationship at DGIdb | |||
Expression of EPYC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPYC | 1833 | 206439_at | 0.9002 | 0.5893 | |
| GSE20347 | EPYC | 1833 | 206439_at | 0.4417 | 0.0005 | |
| GSE23400 | EPYC | 1833 | 206439_at | 0.1749 | 0.0252 | |
| GSE26886 | EPYC | 1833 | 206439_at | 0.0492 | 0.6314 | |
| GSE29001 | EPYC | 1833 | 206439_at | -0.0246 | 0.8174 | |
| GSE38129 | EPYC | 1833 | 206439_at | 0.8446 | 0.0001 | |
| GSE45670 | EPYC | 1833 | 206439_at | 0.1124 | 0.1118 | |
| GSE53622 | EPYC | 1833 | 21703 | 3.4384 | 0.0000 | |
| GSE53624 | EPYC | 1833 | 21703 | 3.6304 | 0.0000 | |
| GSE63941 | EPYC | 1833 | 206439_at | -0.1486 | 0.1578 | |
| GSE77861 | EPYC | 1833 | 206439_at | 0.0368 | 0.6181 | |
| TCGA | EPYC | 1833 | RNAseq | 2.1176 | 0.0071 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by EPYC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPYC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPYC | 1833 | 3 | 2 | 25 | |
| GSE20123 | EPYC | 1833 | 3 | 2 | 25 | |
| GSE43470 | EPYC | 1833 | 3 | 0 | 40 | |
| GSE46452 | EPYC | 1833 | 9 | 1 | 49 | |
| GSE47630 | EPYC | 1833 | 10 | 1 | 29 | |
| GSE54993 | EPYC | 1833 | 0 | 6 | 64 | |
| GSE54994 | EPYC | 1833 | 6 | 1 | 46 | |
| GSE60625 | EPYC | 1833 | 0 | 0 | 11 | |
| GSE74703 | EPYC | 1833 | 3 | 0 | 33 | |
| GSE74704 | EPYC | 1833 | 1 | 2 | 17 | |
| TCGA | EPYC | 1833 | 17 | 12 | 67 |
Total number of gains: 55; Total number of losses: 27; Total Number of normals: 406.
Somatic mutations of EPYC:
Generating mutation plots.
Highly correlated genes for EPYC:
Showing top 20/150 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPYC | IL4I1 | 0.736329 | 3 | 0 | 3 |
| EPYC | IL15RA | 0.692869 | 3 | 0 | 3 |
| EPYC | NETO1 | 0.66481 | 3 | 0 | 3 |
| EPYC | SALL4 | 0.655505 | 4 | 0 | 4 |
| EPYC | AZIN2 | 0.655133 | 3 | 0 | 3 |
| EPYC | ZMIZ2 | 0.654245 | 3 | 0 | 3 |
| EPYC | PLOD2 | 0.651626 | 3 | 0 | 3 |
| EPYC | CXCL10 | 0.649294 | 3 | 0 | 3 |
| EPYC | HAPLN3 | 0.634529 | 3 | 0 | 3 |
| EPYC | PARP14 | 0.633258 | 3 | 0 | 3 |
| EPYC | GXYLT2 | 0.631923 | 3 | 0 | 3 |
| EPYC | REC8 | 0.629848 | 3 | 0 | 3 |
| EPYC | APOC1 | 0.629527 | 5 | 0 | 4 |
| EPYC | CPLX1 | 0.628643 | 3 | 0 | 3 |
| EPYC | SFRP4 | 0.621493 | 8 | 0 | 7 |
| EPYC | GPX8 | 0.618998 | 3 | 0 | 3 |
| EPYC | SPATA17 | 0.617511 | 3 | 0 | 3 |
| EPYC | STAT1 | 0.616392 | 3 | 0 | 3 |
| EPYC | CCDC26 | 0.615327 | 3 | 0 | 3 |
| EPYC | COL10A1 | 0.61177 | 8 | 0 | 5 |
For details and further investigation, click here
