NETO1

 

Full name: neuropilin and tolloid like 1 Alias Symbol: BTCL1|BCTL1
Type: protein-coding gene Cytoband: 18q22.3
Entrez ID: 81832 HGNC ID: HGNC:13823 Ensembl Gene: ENSG00000166342 OMIM ID: 607973
Drug and gene relationship at DGIdb

 

Expression of NETO1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NETO1 81832 236440_at 0.0077 0.9816
GSE26886 NETO1 81832 1562713_a_at 0.0455 0.6494
GSE45670 NETO1 81832 236440_at 0.0137 0.8935
GSE53622 NETO1 81832 73550 1.5249 0.0000
GSE53624 NETO1 81832 73550 1.2980 0.0000
GSE63941 NETO1 81832 1562713_a_at -0.5894 0.0353
GSE77861 NETO1 81832 236440_at -0.1366 0.1425
SRP007169 NETO1 81832 RNAseq 4.3349 0.0006
SRP133303 NETO1 81832 RNAseq 4.1272 0.0000
SRP159526 NETO1 81832 RNAseq 1.5414 0.0972
TCGA NETO1 81832 RNAseq 1.4185 0.0159

Upregulated datasets: 5; Downregulated datasets: 0.  


 

Survival by NETO1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NETO1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NETO1 81832 0 10 20
GSE20123 NETO1 81832 0 10 20
GSE43470 NETO1 81832 0 6 37
GSE46452 NETO1 81832 1 26 32
GSE47630 NETO1 81832 5 21 14
GSE54993 NETO1 81832 9 0 61
GSE54994 NETO1 81832 0 20 33
GSE60625 NETO1 81832 0 4 7
GSE74703 NETO1 81832 0 6 30
GSE74704 NETO1 81832 0 8 12
TCGA NETO1 81832 6 48 42

Total number of gains: 21; Total number of losses: 159; Total Number of normals: 308.  


 

Somatic mutations of NETO1:

 

Generating mutation plots.

 

Highly correlated genes for NETO1:

 

Showing top 20/54 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NETO1ADAMTS120.722054303
NETO1NOG0.676323303
NETO1CTSK0.675202303
NETO1EPYC0.66481303
NETO1LRRC150.6613504
NETO1SAMD9L0.660795303
NETO1OR5P30.657358303
NETO1POSTN0.642755303
NETO1ESM10.632186303
NETO1SPARC0.623002303
NETO1COL1A10.621947303
NETO1ZNF582-AS10.621346303
NETO1NOX40.618948404
NETO1COL11A10.616652503
NETO1ISLR0.609438303
NETO1COL12A10.606889303
NETO1VCAN0.605044303
NETO1RCN30.604573403
NETO1OLR10.600833403
NETO1COL8A10.594973303

For details and further investigation, click here