| Full name: espin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 83715 | HGNC ID: HGNC:13281 | Ensembl Gene: ENSG00000187017 | OMIM ID: 606351 |
| Drug and gene relationship at DGIdb | |||
Expression of ESPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESPN | 83715 | 223549_s_at | 0.1738 | 0.7378 | |
| GSE26886 | ESPN | 83715 | 223549_s_at | 0.4836 | 0.0166 | |
| GSE45670 | ESPN | 83715 | 223549_s_at | 0.3281 | 0.0027 | |
| GSE53622 | ESPN | 83715 | 46743 | -0.0088 | 0.9793 | |
| GSE53624 | ESPN | 83715 | 46743 | -0.1744 | 0.2179 | |
| GSE63941 | ESPN | 83715 | 223549_s_at | 1.4679 | 0.0085 | |
| GSE77861 | ESPN | 83715 | 223549_s_at | -0.0204 | 0.9542 | |
| GSE97050 | ESPN | 83715 | A_32_P901770 | 0.8228 | 0.3417 | |
| SRP007169 | ESPN | 83715 | RNAseq | 0.5610 | 0.2731 | |
| SRP008496 | ESPN | 83715 | RNAseq | 0.9803 | 0.0051 | |
| SRP064894 | ESPN | 83715 | RNAseq | 0.0078 | 0.9854 | |
| SRP133303 | ESPN | 83715 | RNAseq | -0.0133 | 0.9516 | |
| SRP159526 | ESPN | 83715 | RNAseq | -0.2456 | 0.5441 | |
| SRP193095 | ESPN | 83715 | RNAseq | 0.0229 | 0.9315 | |
| SRP219564 | ESPN | 83715 | RNAseq | 0.5200 | 0.5798 | |
| TCGA | ESPN | 83715 | RNAseq | 1.2487 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ESPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESPN | 83715 | 3 | 6 | 21 | |
| GSE20123 | ESPN | 83715 | 3 | 5 | 22 | |
| GSE43470 | ESPN | 83715 | 6 | 5 | 32 | |
| GSE46452 | ESPN | 83715 | 7 | 1 | 51 | |
| GSE47630 | ESPN | 83715 | 8 | 4 | 28 | |
| GSE54993 | ESPN | 83715 | 3 | 2 | 65 | |
| GSE54994 | ESPN | 83715 | 14 | 3 | 36 | |
| GSE60625 | ESPN | 83715 | 0 | 0 | 11 | |
| GSE74703 | ESPN | 83715 | 5 | 3 | 28 | |
| GSE74704 | ESPN | 83715 | 3 | 0 | 17 | |
| TCGA | ESPN | 83715 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of ESPN:
Generating mutation plots.
Highly correlated genes for ESPN:
Showing top 20/322 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESPN | PPP4C | 0.72267 | 3 | 0 | 3 |
| ESPN | WDR5B | 0.707836 | 3 | 0 | 3 |
| ESPN | KRTCAP3 | 0.705453 | 3 | 0 | 3 |
| ESPN | PPP1R14B | 0.678659 | 3 | 0 | 3 |
| ESPN | MIR205HG | 0.666514 | 3 | 0 | 3 |
| ESPN | RPS24 | 0.665084 | 3 | 0 | 3 |
| ESPN | SP140L | 0.657641 | 4 | 0 | 4 |
| ESPN | LIMK2 | 0.650128 | 3 | 0 | 3 |
| ESPN | CHMP4C | 0.64973 | 4 | 0 | 3 |
| ESPN | TOPBP1 | 0.644472 | 4 | 0 | 4 |
| ESPN | BIK | 0.642097 | 4 | 0 | 4 |
| ESPN | JUP | 0.640925 | 5 | 0 | 4 |
| ESPN | SCAMP4 | 0.633032 | 3 | 0 | 3 |
| ESPN | PDZK1 | 0.630552 | 3 | 0 | 3 |
| ESPN | E2F8 | 0.628965 | 4 | 0 | 4 |
| ESPN | RMI1 | 0.62865 | 3 | 0 | 3 |
| ESPN | SAMD10 | 0.627758 | 4 | 0 | 3 |
| ESPN | KCTD1 | 0.625961 | 4 | 0 | 4 |
| ESPN | LPAR3 | 0.624942 | 4 | 0 | 3 |
| ESPN | PPFIA1 | 0.623597 | 3 | 0 | 3 |
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