| Full name: ethanolamine kinase 2 | Alias Symbol: FLJ10761|EKI2 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 55224 | HGNC ID: HGNC:25575 | Ensembl Gene: ENSG00000143845 | OMIM ID: 609859 |
| Drug and gene relationship at DGIdb | |||
Expression of ETNK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETNK2 | 55224 | 219268_at | 0.6433 | 0.2313 | |
| GSE20347 | ETNK2 | 55224 | 219268_at | -0.2543 | 0.4148 | |
| GSE23400 | ETNK2 | 55224 | 219268_at | -0.1717 | 0.0184 | |
| GSE26886 | ETNK2 | 55224 | 219268_at | -0.1429 | 0.6573 | |
| GSE29001 | ETNK2 | 55224 | 219268_at | -0.1177 | 0.4861 | |
| GSE38129 | ETNK2 | 55224 | 219268_at | -0.0982 | 0.6880 | |
| GSE45670 | ETNK2 | 55224 | 219268_at | -0.6199 | 0.0003 | |
| GSE53622 | ETNK2 | 55224 | 16935 | -0.2722 | 0.2142 | |
| GSE53624 | ETNK2 | 55224 | 16935 | -0.4853 | 0.0007 | |
| GSE63941 | ETNK2 | 55224 | 219268_at | 0.6628 | 0.0847 | |
| GSE77861 | ETNK2 | 55224 | 219268_at | 0.1867 | 0.6246 | |
| GSE97050 | ETNK2 | 55224 | A_23_P46025 | -0.5602 | 0.3562 | |
| SRP007169 | ETNK2 | 55224 | RNAseq | -1.8742 | 0.0005 | |
| SRP008496 | ETNK2 | 55224 | RNAseq | -1.3940 | 0.0394 | |
| SRP064894 | ETNK2 | 55224 | RNAseq | -0.8824 | 0.0056 | |
| SRP133303 | ETNK2 | 55224 | RNAseq | -0.9176 | 0.0033 | |
| SRP159526 | ETNK2 | 55224 | RNAseq | 1.1013 | 0.0653 | |
| SRP193095 | ETNK2 | 55224 | RNAseq | -0.8599 | 0.0151 | |
| SRP219564 | ETNK2 | 55224 | RNAseq | 0.4711 | 0.6031 | |
| TCGA | ETNK2 | 55224 | RNAseq | 0.2887 | 0.1003 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ETNK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETNK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETNK2 | 55224 | 11 | 0 | 19 | |
| GSE20123 | ETNK2 | 55224 | 11 | 0 | 19 | |
| GSE43470 | ETNK2 | 55224 | 6 | 0 | 37 | |
| GSE46452 | ETNK2 | 55224 | 3 | 1 | 55 | |
| GSE47630 | ETNK2 | 55224 | 14 | 0 | 26 | |
| GSE54993 | ETNK2 | 55224 | 0 | 6 | 64 | |
| GSE54994 | ETNK2 | 55224 | 15 | 0 | 38 | |
| GSE60625 | ETNK2 | 55224 | 0 | 0 | 11 | |
| GSE74703 | ETNK2 | 55224 | 6 | 0 | 30 | |
| GSE74704 | ETNK2 | 55224 | 5 | 0 | 15 | |
| TCGA | ETNK2 | 55224 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of ETNK2:
Generating mutation plots.
Highly correlated genes for ETNK2:
Showing top 20/53 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETNK2 | ALDH5A1 | 0.677755 | 3 | 0 | 3 |
| ETNK2 | ZNF385C | 0.676607 | 3 | 0 | 3 |
| ETNK2 | TMEM115 | 0.667276 | 3 | 0 | 3 |
| ETNK2 | KCTD1 | 0.649478 | 3 | 0 | 3 |
| ETNK2 | MCRS1 | 0.646044 | 3 | 0 | 3 |
| ETNK2 | UBR7 | 0.634 | 3 | 0 | 3 |
| ETNK2 | LHX6 | 0.633451 | 3 | 0 | 3 |
| ETNK2 | CNOT10 | 0.628235 | 3 | 0 | 3 |
| ETNK2 | INO80E | 0.626071 | 3 | 0 | 3 |
| ETNK2 | PTPN13 | 0.620272 | 3 | 0 | 3 |
| ETNK2 | ZNHIT2 | 0.618376 | 4 | 0 | 3 |
| ETNK2 | SMARCD1 | 0.615668 | 4 | 0 | 4 |
| ETNK2 | PRR3 | 0.609422 | 4 | 0 | 3 |
| ETNK2 | ASPG | 0.60673 | 3 | 0 | 3 |
| ETNK2 | GPR160 | 0.604989 | 3 | 0 | 3 |
| ETNK2 | LIG3 | 0.598407 | 3 | 0 | 3 |
| ETNK2 | TOPBP1 | 0.597924 | 3 | 0 | 3 |
| ETNK2 | CUL7 | 0.597367 | 3 | 0 | 3 |
| ETNK2 | EFNB3 | 0.592062 | 4 | 0 | 3 |
| ETNK2 | PRMT6 | 0.58769 | 3 | 0 | 3 |
For details and further investigation, click here
