| Full name: ETS variant transcription factor 4 | Alias Symbol: E1A-F|E1AF|PEA3 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 2118 | HGNC ID: HGNC:3493 | Ensembl Gene: ENSG00000175832 | OMIM ID: 600711 |
| Related drugs: TRAMETINIB... [more] | |||
Expression of ETV4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV4 | 2118 | 211603_s_at | 0.4069 | 0.5851 | |
| GSE20347 | ETV4 | 2118 | 211603_s_at | 0.3315 | 0.0428 | |
| GSE23400 | ETV4 | 2118 | 211603_s_at | 0.3314 | 0.0000 | |
| GSE26886 | ETV4 | 2118 | 211603_s_at | 0.3373 | 0.0248 | |
| GSE29001 | ETV4 | 2118 | 211603_s_at | 0.4055 | 0.1672 | |
| GSE38129 | ETV4 | 2118 | 211603_s_at | 0.4416 | 0.0065 | |
| GSE45670 | ETV4 | 2118 | 1554576_a_at | 0.1552 | 0.1503 | |
| GSE53622 | ETV4 | 2118 | 19522 | 1.8083 | 0.0000 | |
| GSE53624 | ETV4 | 2118 | 19522 | 1.5789 | 0.0000 | |
| GSE63941 | ETV4 | 2118 | 1554576_a_at | 1.1688 | 0.1539 | |
| GSE77861 | ETV4 | 2118 | 1554576_a_at | 0.4589 | 0.0533 | |
| GSE97050 | ETV4 | 2118 | A_24_P416346 | 0.6649 | 0.1832 | |
| SRP007169 | ETV4 | 2118 | RNAseq | 1.5860 | 0.0004 | |
| SRP008496 | ETV4 | 2118 | RNAseq | 1.9363 | 0.0000 | |
| SRP064894 | ETV4 | 2118 | RNAseq | 1.1688 | 0.0040 | |
| SRP133303 | ETV4 | 2118 | RNAseq | 1.2649 | 0.0000 | |
| SRP159526 | ETV4 | 2118 | RNAseq | 2.8458 | 0.0000 | |
| SRP193095 | ETV4 | 2118 | RNAseq | 1.2919 | 0.0000 | |
| SRP219564 | ETV4 | 2118 | RNAseq | -0.0669 | 0.9303 | |
| TCGA | ETV4 | 2118 | RNAseq | 1.1789 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by ETV4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV4 | 2118 | 5 | 2 | 23 | |
| GSE20123 | ETV4 | 2118 | 5 | 2 | 23 | |
| GSE43470 | ETV4 | 2118 | 1 | 2 | 40 | |
| GSE46452 | ETV4 | 2118 | 32 | 0 | 27 | |
| GSE47630 | ETV4 | 2118 | 8 | 1 | 31 | |
| GSE54993 | ETV4 | 2118 | 3 | 4 | 63 | |
| GSE54994 | ETV4 | 2118 | 8 | 5 | 40 | |
| GSE60625 | ETV4 | 2118 | 4 | 0 | 7 | |
| GSE74703 | ETV4 | 2118 | 1 | 1 | 34 | |
| GSE74704 | ETV4 | 2118 | 3 | 1 | 16 | |
| TCGA | ETV4 | 2118 | 25 | 6 | 65 |
Total number of gains: 95; Total number of losses: 24; Total Number of normals: 369.
Somatic mutations of ETV4:
Generating mutation plots.
Highly correlated genes for ETV4:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV4 | FANCB | 0.78297 | 4 | 0 | 4 |
| ETV4 | UCK2 | 0.740753 | 3 | 0 | 3 |
| ETV4 | DKC1 | 0.734494 | 3 | 0 | 3 |
| ETV4 | TICRR | 0.69563 | 3 | 0 | 3 |
| ETV4 | PON3 | 0.685352 | 3 | 0 | 3 |
| ETV4 | SLC19A1 | 0.683442 | 3 | 0 | 3 |
| ETV4 | SLC25A39 | 0.679627 | 3 | 0 | 3 |
| ETV4 | NLN | 0.67692 | 4 | 0 | 4 |
| ETV4 | SIX4 | 0.676371 | 6 | 0 | 5 |
| ETV4 | SNAP47 | 0.669706 | 3 | 0 | 3 |
| ETV4 | CDCA7 | 0.666951 | 3 | 0 | 3 |
| ETV4 | FAM89A | 0.665766 | 3 | 0 | 3 |
| ETV4 | ANAPC1 | 0.662815 | 3 | 0 | 3 |
| ETV4 | MMS22L | 0.662499 | 3 | 0 | 3 |
| ETV4 | SPRED1 | 0.6585 | 3 | 0 | 3 |
| ETV4 | MTBP | 0.657699 | 4 | 0 | 3 |
| ETV4 | SPPL2A | 0.657291 | 3 | 0 | 3 |
| ETV4 | TAF1C | 0.65705 | 3 | 0 | 3 |
| ETV4 | TOP2A | 0.655675 | 7 | 0 | 5 |
| ETV4 | FAM83B | 0.654945 | 4 | 0 | 3 |
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