| Full name: fatty acid amide hydrolase | Alias Symbol: FAAH-1 | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 2166 | HGNC ID: HGNC:3553 | Ensembl Gene: ENSG00000117480 | OMIM ID: 602935 |
| Drug and gene relationship at DGIdb | |||
Expression of FAAH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAAH | 2166 | 204231_s_at | 0.1878 | 0.5390 | |
| GSE20347 | FAAH | 2166 | 204231_s_at | -0.0200 | 0.8965 | |
| GSE23400 | FAAH | 2166 | 204231_s_at | -0.0340 | 0.4853 | |
| GSE26886 | FAAH | 2166 | 204231_s_at | 0.0356 | 0.8352 | |
| GSE29001 | FAAH | 2166 | 204231_s_at | -0.1222 | 0.5296 | |
| GSE38129 | FAAH | 2166 | 204231_s_at | 0.1063 | 0.3909 | |
| GSE45670 | FAAH | 2166 | 204231_s_at | 0.1236 | 0.3467 | |
| GSE53622 | FAAH | 2166 | 29681 | -0.3046 | 0.0573 | |
| GSE53624 | FAAH | 2166 | 29681 | -0.3643 | 0.0014 | |
| GSE63941 | FAAH | 2166 | 204231_s_at | 0.7869 | 0.0574 | |
| GSE77861 | FAAH | 2166 | 204231_s_at | -0.1178 | 0.6198 | |
| GSE97050 | FAAH | 2166 | A_23_P103226 | -0.0884 | 0.6310 | |
| SRP007169 | FAAH | 2166 | RNAseq | -0.3119 | 0.6260 | |
| SRP064894 | FAAH | 2166 | RNAseq | 0.2801 | 0.4168 | |
| SRP133303 | FAAH | 2166 | RNAseq | -0.0143 | 0.9611 | |
| SRP159526 | FAAH | 2166 | RNAseq | -0.8753 | 0.0550 | |
| SRP193095 | FAAH | 2166 | RNAseq | -0.2369 | 0.2729 | |
| SRP219564 | FAAH | 2166 | RNAseq | -0.4154 | 0.4408 | |
| TCGA | FAAH | 2166 | RNAseq | -0.4634 | 0.0071 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAAH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAAH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAAH | 2166 | 4 | 3 | 23 | |
| GSE20123 | FAAH | 2166 | 4 | 2 | 24 | |
| GSE43470 | FAAH | 2166 | 5 | 1 | 37 | |
| GSE46452 | FAAH | 2166 | 2 | 1 | 56 | |
| GSE47630 | FAAH | 2166 | 8 | 4 | 28 | |
| GSE54993 | FAAH | 2166 | 0 | 1 | 69 | |
| GSE54994 | FAAH | 2166 | 11 | 2 | 40 | |
| GSE60625 | FAAH | 2166 | 0 | 0 | 11 | |
| GSE74703 | FAAH | 2166 | 4 | 1 | 31 | |
| GSE74704 | FAAH | 2166 | 2 | 0 | 18 | |
| TCGA | FAAH | 2166 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of FAAH:
Generating mutation plots.
Highly correlated genes for FAAH:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAAH | HOXA11 | 0.761719 | 3 | 0 | 3 |
| FAAH | MARVELD3 | 0.691694 | 3 | 0 | 3 |
| FAAH | SETD1B | 0.671959 | 3 | 0 | 3 |
| FAAH | CYP11B1 | 0.668737 | 3 | 0 | 3 |
| FAAH | PARS2 | 0.647562 | 3 | 0 | 3 |
| FAAH | SHC2 | 0.636879 | 3 | 0 | 3 |
| FAAH | POLL | 0.634308 | 4 | 0 | 4 |
| FAAH | ZNF219 | 0.619871 | 5 | 0 | 4 |
| FAAH | PIP5K1A | 0.616352 | 3 | 0 | 3 |
| FAAH | CNGB3 | 0.611876 | 4 | 0 | 3 |
| FAAH | PPFIA3 | 0.610901 | 4 | 0 | 3 |
| FAAH | OPRD1 | 0.606728 | 4 | 0 | 3 |
| FAAH | LYG1 | 0.59509 | 3 | 0 | 3 |
| FAAH | DLX3 | 0.582944 | 3 | 0 | 3 |
| FAAH | ZBTB48 | 0.580135 | 5 | 0 | 4 |
| FAAH | INF2 | 0.575125 | 5 | 0 | 3 |
| FAAH | TMEM63A | 0.571685 | 4 | 0 | 3 |
| FAAH | PTOV1-AS1 | 0.570502 | 3 | 0 | 3 |
| FAAH | DCAF15 | 0.568641 | 4 | 0 | 3 |
| FAAH | EMID1 | 0.566287 | 4 | 0 | 3 |
For details and further investigation, click here
